Alternatived Products of [ 685-73-4 ]
Product Details of [ 685-73-4 ]
CAS No. : | 685-73-4 |
MDL No. : | MFCD00006618 |
Formula : |
C6H10O7
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
194.14
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 685-73-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 685-73-4 ]
- Downstream synthetic route of [ 685-73-4 ]
- 1
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[ 685-73-4 ]
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[ 499-05-8 ]
- 2
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[ 685-73-4 ]
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[ 1668-08-2 ]
- 3
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Taishan P. massonianapollen polysaccharide
[ No CAS ]
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[ 58-86-6 ]
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[ 3458-28-4 ]
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[ 10323-20-3 ]
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[ 50-69-1 ]
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[ 59-23-4 ]
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[ 4205-23-6 ]
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[ 6556-12-3 ]
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[ 685-73-4 ]
Yield | Reaction Conditions | Operation in experiment |
|
With trifluoroacetic acid at 110℃; |
2.1.2 Extraction, purification and isolation of polysaccharide
We detected the composition and content of monosaccharide in TPPPS by precolumn derivatization ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry. TPPPS was cleaned with C18 SPE cartridge, and then hydrolysised with TFA at 110°C. The products were derivated with 50μL 0.2mol/L 1-phenyl-3-methyl-5-pyrazolone (PMP) for 30min. The obtained monosaccharides were separated at a flow rate of 0.5mL/min on a Waters ACQUITY UPLC BEH C18 column (2.1mm i. d.×50mm, 1.7μm) at 37°C, by using acetonitrile and buffered salt solution (0.5mmol/L ammonium acetate and 0.05% acetic acid) as the mobile phase in the gradient elution. The analysis of target compounds was performed in multiple reaction monitoring (MRM) mode via positive electrospray ionization, and quantified by the internal standard method. |
Reference:
[1]Guo, Fanxia; Xue, Cong; Wu, Cun; Zhao, Xue; Qu, Tinghe; He, Xiaohua; Guo, Zhongkun; Zhu, Ruiliang
[Carbohydrate Polymers, 2014, vol. 109, p. 71 - 76]
- 4
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[ 685-73-4 ]
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[ 4282-32-0 ]
- 5
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myricetin 3-O-β-4C1-galactopyranouronoide
[ No CAS ]
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[ 685-73-4 ]
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[ 529-44-2 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride; In water; at 100℃; for 2h; |
Complete acid hydrolysis of 14 (11 mg in 5 ml, 2 N aq. HCl, at 100 Cfor 2 h) yielded myricetin and galacturonic acid; |
- 6
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[ 173140-90-4 ]
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[ 312753-70-1 ]
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[ 685-73-4 ]
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5-[(R)-2-(5,6-diethylindan-2-yl-amino)-1-hydroxyethyl]-8-benzyloxy-(1H)-quinolin-2-one galacturonic acid
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
79.8% |
Stage #1: (R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone; 5,6-diethyl-2,3-dihydro-1H-inden-2-amine In butanone at 70℃; for 6h;
Stage #2: D-galacturonic acid In ethanol; butanone at 60℃; for 0.0833333h; |
2 Example 25-[(R)-2-(5,6-Diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-benzyloxy-(1H)-quinoline-Preparation of 2-ketogalacturonate
8-Benzyloxy-5-(R)-oxiranyl-(1H)-quinolin-2-one (32.02 g, 110 mmoL) dissolved in 130 mLIn methyl ethyl ketone,2-amino-(5,6-diethyl)-indane (18.92 g, 100 mmoL) was added and the reaction was stirred at 70°C for 6 hours.TLC test showed that the reaction was complete.The resulting brown solution was cooled to 60° C., 160 mL of ethanol was added and maintained at 60° C., and then a pre-prepared solution of 85.36 g (440 mmol) of galacturonic acid in 160 mL of ethanol was added and the reaction was stirred for 5 minutes.To about 40 °C, seed crystals were added and placed in an ice bath to cool.5-[(R)-2-(5,6-Diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-benzyloxy-(1H)-quinoline- 2-Ketogalacturonate crude 56.7g,Recrystallization from ethanol gave 54.0 g of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-benzyloxy-( 1H)-quinolin-2-one galacturonic acid pure product as a white crystalline powder (total yield 79.8%, purity 98.71%). |
- 7
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[ 685-73-4 ]
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[ 98-01-1 ]
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[ 35942-09-7 ]
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[ 6005-10-3 ]
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[ 19322-27-1 ]
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[ 1197-09-7 ]
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[ 24677-78-9 ]
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[ 120-80-9 ]
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[ 488-17-5 ]
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