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Chemical Structure| 69731-52-8 Chemical Structure| 69731-52-8

Structure of 69731-52-8

Chemical Structure| 69731-52-8

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Product Details of [ 69731-52-8 ]

CAS No. :69731-52-8
Formula : C9H12N2O4
M.W : 212.20
SMILES Code : O=C(C1=CN=C(COC)N=C1O)OCC

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Application In Synthesis of [ 69731-52-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 69731-52-8 ]

[ 69731-52-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1903-91-9 ]
  • [ 87-13-8 ]
  • [ 69731-52-8 ]
YieldReaction ConditionsOperation in experiment
81% With ethanol; sodium ethanolate; at 90℃; for 17h; A mixture of diethyl 2-(ethoxymethylene)malonate (5 g, 23.2 mmol), <strong>[1903-91-9]2-methoxyacetimidamide hydrochloride</strong> (2.88 g, 23.2 mmol) and sodium ethoxide (3.15 g, 46.3 mmol) in anhydrous ethanol (200 mL) was stirred at 90 C for 17 h. The reaction mixture was concentrated, to give ethyl 4-hydroxy-2-(methoxymethyl)pyrimidine-5-carboxylate (4 g, 18.8 mmol, 81 %) as a white solid. LCMS (ESI) m/z: 213.1 [M+H]+
 

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