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Chemical Structure| 71005-75-9 Chemical Structure| 71005-75-9

Structure of 71005-75-9

Chemical Structure| 71005-75-9

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Product Details of [ 71005-75-9 ]

CAS No. :71005-75-9
Formula : C5H7NO2
M.W : 113.11
SMILES Code : O=C1OC=C(CC)N1

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Application In Synthesis of [ 71005-75-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 71005-75-9 ]

[ 71005-75-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5077-67-8 ]
  • [ 71005-75-9 ]
YieldReaction ConditionsOperation in experiment
With acetic acid; EXAMPLE 3 Preparation of 4-ethyl-4-oxazolin-2-one Potassium cyanate (60 g.) is added to a stirred and cooled (3 C.) solution of 1-hydroxy-2-butanone (30 g.) (2-ketobutanol) in 500 ml. of anhydrous ether. Acetic acid (30 ml.) is added over a period of 10 minutes and the mixture stirred for an additional 3.5 hours whereupon the temperature rises to 16 C. The mixture is kept at room temperature overnight. The ether solution is removed from the solid by decantation. The solid residue is washed twice with ether and discarded. The combined ether solutions is evaporated to leave a yellow oily residue (6.7 g.). The Infrared and Nuclear Magnetic Resonance are compatible with the desired material and the latter indicated its purity to be about 82%.
  • 2
  • potassium cyanide [ No CAS ]
  • [ 5077-67-8 ]
  • [ 71005-75-9 ]
YieldReaction ConditionsOperation in experiment
1.0 g With acetic acid; In diethyl ether; at 20℃; for 12h; A solution of potassium cyanate (6.0 g, 74.07 mmol), <strong>[5077-67-8]1-hydroxybutan-2-one</strong> (3.0 g, 34.05 mmol) in diethyl ether (100 mL) was added acetic acid (3.0 mL, 34.05 mmol) was stirred at 20 C. for 12 h. After filtration, the filtrate was concentrated under reduced pressure to afford 4-ethyl-3H-oxazol-2-one (1.0 g, 8.84 mmol) as yellow oil. LCMS (ESI) [M+H]+=114
 

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