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Chemical Structure| 732976-89-5 Chemical Structure| 732976-89-5

Structure of 732976-89-5

Chemical Structure| 732976-89-5

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Product Details of [ 732976-89-5 ]

CAS No. :732976-89-5
Formula : C9H12N2O3
M.W : 196.20
SMILES Code : CNCC1=CC=C(OC)C([N+]([O-])=O)=C1
MDL No. :MFCD11119297

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Application In Synthesis of [ 732976-89-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 732976-89-5 ]

[ 732976-89-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 74-89-5 ]
  • [ 31680-08-7 ]
  • [ 732976-89-5 ]
YieldReaction ConditionsOperation in experiment
44% <strong>[31680-08-7]4-methoxy-3-nitrobenzaldehyde</strong> (5 g, 27.6 mmol), CH3NH2 (2.0 g, 64.5 mmol) and AcOH (3 mL) were added to MeOH (50 mL). The reaction mixture was stirred at 0oC for 1h. NaBH(OAc)3(2.0 g, 64.5 mmol) was added and then stirred at rt for overnight. The reaction mixture was then poured into water (200 mL), and was extracted with ethyl acetate. The organic layer was washed with HCl (1M), the aqueous layer was basified with NaHCO3 and extracted with ethyl acetate, the organic layer was dried over magnesium sulfate, filtered, and concentrated in vacuo to give title compound 51b.(2 g, 44%). LC- MS (ESI): m/z =197.3 [M+H]+
 

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