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Chemical Structure| 739366-04-2 Chemical Structure| 739366-04-2

Structure of 739366-04-2

Chemical Structure| 739366-04-2

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Product Details of [ 739366-04-2 ]

CAS No. :739366-04-2
Formula : C11H13N3O3
M.W : 235.24
SMILES Code : O=C(C1=CN2C(N=C1)=CC(COC)=N2)OCC

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Application In Synthesis of [ 739366-04-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 739366-04-2 ]

[ 739366-04-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 739366-03-1 ]
  • [ 80370-42-9 ]
  • [ 739366-04-2 ]
YieldReaction ConditionsOperation in experiment
69% In ethanol; Ethyl 2-formyl-3-oxopropionate (775 mg) was added to a solution of the thus obtained 5-methoxymethyl-2H-pyrazol-3-ylamine (684 mg) in ethanol (50 ml), and stirred overnight. The reaction solution was concentrated under reduced pressure, and a saturated sodium bicarbonate solution was added to the residue which were then extracted with ethyl acetate. The organic phase was washed with a saturated saline solution and dried over sodium sulfate anhydrous. The resulting product was concentrated under reduced pressure, and the residue was purified by column chromatography (eluding solvent; n-hexane: ethyl acetate 4: 1) to give ethyl 2-methoxymethylpyrazolo[1,5-a] pyrimidine-6-carboxylate (878 mg, Y.: 69%).
 

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