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Chemical Structure| 7574-64-3 Chemical Structure| 7574-64-3

Structure of 7574-64-3

Chemical Structure| 7574-64-3

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Product Details of [ 7574-64-3 ]

CAS No. :7574-64-3
Formula : C9H7ClN2
M.W : 178.62
SMILES Code : NC1=CC2=C(C(Cl)=N1)C=CC=C2
MDL No. :MFCD18260346
InChI Key :IUXVAIRMPDVFDK-UHFFFAOYSA-N
Pubchem ID :12294534

Safety of [ 7574-64-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 7574-64-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7574-64-3 ]

[ 7574-64-3 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 7574-64-3 ]
  • [ 98-80-6 ]
  • 1-phenylisoquinolin-3-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In 1,4-dioxane; water; toluene; for 12.0h;Reflux; General procedure: [Intermediate 2-b] synthesized in [Scheme 2-2] (44 g, 0.104 mol), 2-bromonnitrobenzene (46,4 g, 0.23 mol), tetrakis (triphenylphosphine) palladium ( 3.62 g, 0.003 mol) and potassium carbonate (72.2 g, 0.522 mol) were added to 278.6 mL of 1,4-dioxane, 278.6 mL of toluene, and 92.8 mL of distilled water and refluxed for 12 hours. After cooling to room temperature, extraction with ethyl acetate, and separation by column chromatography to give [Intermediate 2-c] 31.2 g (61% yield).
 

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