Home Cart 0 Sign in  

[ CAS No. 773-63-7 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 773-63-7
Chemical Structure| 773-63-7
Structure of 773-63-7 *Storage: {[proInfo.prStorage]}

Quality Control of [ 773-63-7 ]

Related Doc. of [ 773-63-7 ]

SDS

Product Details of [ 773-63-7 ]

CAS No. :773-63-7MDL No. :MFCD00614246
Formula : C11H14N2 Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :174.24Pubchem ID :594548
Synonyms :

Computed Properties of [ 773-63-7 ]

TPSA : 38.4 H-Bond Acceptor Count : 2
XLogP3 : 1.6 H-Bond Donor Count : 1
SP3 : 0.36 Rotatable Bond Count : 0

Safety of [ 773-63-7 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 773-63-7 ]

  • Upstream synthesis route of [ 773-63-7 ]
  • Downstream synthetic route of [ 773-63-7 ]

[ 773-63-7 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 3484-22-8 ]
  • [ 773-63-7 ]
YieldReaction ConditionsOperation in experiment
96%
Stage #1: With hydrogenchloride; tin(II) chloride dihdyrate In water for 2.00 h; Reflux
Stage #2: With sodium hydrogencarbonate In water
Example 2
5-amino-2,3,3-trimethyl-(3H)-indole (product B)
A mixture of 6.6 g of product A, 43.7 g of stannous chloride dihydrate and 215 ml of hydrochloric acid is taken to reflux for two hours.
After cooling down to ambient temperature and filtration, the solid collected is solubilized in 130 ml of water.
This solution is neutralized by the addition of 20percent soda.
The precipitate formed is filtered then washed with water and dried under vacuum in the presence of phosphoric anhydride. 5.4 g of product B is obtained (Yield: 96percent).
Reference: [1] Patent: US2012/45851, 2012, A1. Location in patent: Page/Page column 14; 18
[2] Organic and Biomolecular Chemistry, 2012, vol. 10, # 4, p. 710 - 715
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984, vol. 20, # 9, p. 976 - 977[4] Khimiya Geterotsiklicheskikh Soedinenii, 1984, vol. 20, # 9, p. 1198 - 1199
[5] Journal of Physical Chemistry, 1985, vol. 89, # 18, p. 3941 - 3946
  • 2
  • [ 60-29-7 ]
  • [ 3484-22-8 ]
  • [ 773-63-7 ]
Reference: [1] Patent: US2011/230664, 2011, A1
  • 3
  • [ 1640-39-7 ]
  • [ 773-63-7 ]
Reference: [1] Patent: US2012/45851, 2012, A1
Historical Records

Related Functional Groups of
[ 773-63-7 ]

Amines

Chemical Structure| 15889-32-4

[ 15889-32-4 ]

3-(2-Pyridyl)aniline

Similarity: 0.71

Chemical Structure| 581-28-2

[ 581-28-2 ]

Acridin-2-amine

Similarity: 0.71

Chemical Structure| 132833-03-5

[ 132833-03-5 ]

Isoquinolin-3-ylmethanamine

Similarity: 0.71

Chemical Structure| 90-45-9

[ 90-45-9 ]

9-Aminoacridine

Similarity: 0.70

Chemical Structure| 1170936-92-1

[ 1170936-92-1 ]

3-(Pyridin-2-yl)aniline dihydrochloride

Similarity: 0.70

Related Parent Nucleus of
[ 773-63-7 ]

Indoles

Chemical Structure| 5418-63-3

[ 5418-63-3 ]

1,2,3,3-Tetramethyl-3H-indolium iodide

Similarity: 0.85

Chemical Structure| 25981-83-3

[ 25981-83-3 ]

5-Chloro-2,3,3-trimethyl-3H-indole

Similarity: 0.73

Chemical Structure| 59223-23-3

[ 59223-23-3 ]

5-Hydroxy-1,2,3,3-tetramethyl-3H-indol-1-ium iodide

Similarity: 0.73

Chemical Structure| 3484-22-8

[ 3484-22-8 ]

2,3,3-Trimethyl-5-nitro-3H-indole

Similarity: 0.72

Chemical Structure| 92462-70-9

[ 92462-70-9 ]

5-(tert-Butyl)-1H-indole

Similarity: 0.58