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Chemical Structure| 7773-83-3 Chemical Structure| 7773-83-3

Structure of 7773-83-3

Chemical Structure| 7773-83-3

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Product Details of [ 7773-83-3 ]

CAS No. :7773-83-3
Formula : C22H46S
M.W : 342.67
SMILES Code : CCCCCCCCCCCCCCCCCCCCCCS
English Name :1-Docosanethiol
MDL No. :MFCD02262163

Safety of [ 7773-83-3 ]

Application In Synthesis of [ 7773-83-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7773-83-3 ]

[ 7773-83-3 ] Synthesis Path-Downstream   1~11

  • 1
  • [ CAS Unavailable ]
  • [ 7773-83-3 ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide In tetrahydrofuran at 50℃; for 0.5h;
  • 3
  • [ 6938-66-5 ]
  • [ 62-56-6 ]
  • [ 7773-83-3 ]
YieldReaction ConditionsOperation in experiment
Stage #1: 1-Bromodocosane; thiourea In ethanol for 12h; Heating; Stage #2: With potassium hydroxide In ethanol for 4h; Heating;
  • 4
  • [ 6938-66-5 ]
  • [ 7773-83-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 60 percent / aq. sodium thiosulfate pentahydrate / ethanol / 72 h / Heating 2: 87 percent / aq. HCl / 2 h / Heating
Multi-step reaction with 2 steps 1: tetrahydrofuran / 18 h / 80 °C 2: KOH / tetrahydrofuran / 0.5 h / 50 °C
  • 6
  • [ 108-30-5 ]
  • [ 7773-83-3 ]
  • [ 2509377-32-4 ]
YieldReaction ConditionsOperation in experiment
96% With pyridine at 20 - 50℃; for 40h; Inert atmosphere; General Procedure for the synthesis of compounds 9a-9f General procedure: To a stirred solution of alkane-1-thiol (4.90 mmol, 1.00 eq) in pyridine (9.80 mL, 0.50 M) was added succinic anhydride (0.73 g, 7.30 mmol, 1.50 eq) at room temperature and the resulting mixture was stirred for 24-48 h at 40-50 °C. The reaction mixture was allowed to cool to room temperature and poured into aqueous potassium hydrogen sulfate (5%, 100 mL). The resulting reaction mixture was extracted with DCM (50 mL × 2). The combined organic layers were washed with brine (100 mL × 2), dried over sodium sulfate, and concentrated in vacuo. The residue was purified by recrystallization from DCM (20 mL) or chloroform (20 mL) at 35 °C and allowed to cool at 4 °C to afford 4-(alkylthio)-4-oxobutanoic acid in 87-96% yield as a colorless solid or crystal.
  • 7
  • [ 7773-83-3 ]
  • [ 2488373-36-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: pyridine / 40 h / 20 - 50 °C / Inert atmosphere 2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 21 h / 20 °C / Inert atmosphere
  • 8
  • [ 7773-83-3 ]
  • [ 2488373-41-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: pyridine / 40 h / 20 - 50 °C / Inert atmosphere 2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 21 h / 20 °C / Inert atmosphere 3: Amberlyst 15® / methanol / 5 h / 20 °C / Inert atmosphere
  • 9
  • [ 2768-02-7 ]
  • [ 7773-83-3 ]
  • [ 3103894-97-6 ]
YieldReaction ConditionsOperation in experiment
6.98 g With dimethyl 2,2'-azobis(isobutyrate) In toluene at 50℃; for 8h; 39 [Synthesis Example 39] 5.00 g (1.46 x 10-2 mol) of the compound represented by the following formula (BJ), 40.00 g of toluene, 2.38 g (1.61 x 10-2 mol) of vinyltrimethoxysilane, and 4.56 x 10-1 g (1.98 x 10-3 mol) of dimethyl 2,2'-azobis(isobutyrate) were mixed in a reaction vessel and aged at 50°C for 8 hours. The solvent and unreacted materials were then distilled off under reduced pressure to obtain 6.98 g of product.
  • 10
  • [ 7773-83-3 ]
  • [ 52217-57-9 ]
  • [ 3103894-87-4 ]
YieldReaction ConditionsOperation in experiment
6.55 g With dimethyl 2,2'-azobis(isobutyrate) In toluene at 50℃; for 8h; 29 [Synthesis Example 29] 5.00 g (1.46 x 10-2 mol) of the compound represented by the following formula (BJ), 40.00 g of toluene, 4.07 g (1.75 x 10-2 mol) of trimethoxy(7-octen-1-yl)silane, and 4.56 x 10-1 g (1.98 x 10-3 mol) of dimethyl 2,2'-azobis(isobutyrate) were mixed in a reaction vessel and aged at 50°C for 8 hours. The solvent and unreacted materials were then distilled off under reduced pressure to obtain 6.55 g of product.
  • 11
  • [ 7773-83-3 ]
  • [ 31698-14-3 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
86% With N,N,N',N'-tetramethylguanidine In N,N-dimethyl-formamide at 100℃; for 24h; 1.1.6 Synthesis of Compound 29: 6.0 g of compound 5, 10.90 g of 1-docoethanethiol, 7.93 g of tetramethylguanidine, and 120 mL of N,N-dimethylformamide were added to a 250 mL single-necked flask. The mixture was stirred at 100 °C for 24 hours. After the reaction was complete, the reaction solution was extracted with ethyl acetate and water. The upper organic phase was washed successively with water and saturated brine, dried over anhydrous sodium sulfate, and filtered. The collected organic phase was concentrated under vacuum and purified by silica gel column chromatography (n-heptane/ethyl acetate) to give 10.5 g of compound 29, in 86% yield.
 

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