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Chemical Structure| 81866-98-0 Chemical Structure| 81866-98-0

Structure of 81866-98-0

Chemical Structure| 81866-98-0

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Product Details of [ 81866-98-0 ]

CAS No. :81866-98-0
Formula : C6H8N2O3
M.W : 156.14
SMILES Code : O=C(N1)NC2(COCC2)C1=O
MDL No. :MFCD18333462

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Application In Synthesis of [ 81866-98-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 81866-98-0 ]

[ 81866-98-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 22929-52-8 ]
  • [ 151-50-8 ]
  • [ 506-87-6 ]
  • [ 81866-98-0 ]
  • 2
  • [ 22929-52-8 ]
  • [ 81866-98-0 ]
YieldReaction ConditionsOperation in experiment
With ammonium carbonate; In ethanol; water; EXAMPLE 1 7-Oxa-1,3-diazaspiro[4.4]nonane-2,4-dione STR8 A solution of 19.2 g of ammonium carbonate in 42 ml of ethanol and 28 ml of water is added to 10.0 g of 3-ketotetrahydrofuran. The resulting mixture is heated to 55° and to it is then added, dropwise, a solution of 6.3 g of potassium cyanide in 15 ml of water. The reaction mixture is stirred at 55° for 18 hrs. Thereafter the reaction mixture is evaporated in vacuo to dryness to obtain a residue. The residue is dissolved in a minimum of water and the mixture made acidic with 2 N hydrochloric acid. The first crop of the title product precipitates out on cooling and is filtered off. A second crop of the title product is obtained by concentrating the filtrate and cooling. The two combined crops are recrystallized from ethanol to give refined title product, m.p. 202°-204°.
 

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