Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
*Storage: {[proInfo.prStorage]}
CAS No. : | 82657-71-4 | MDL No. : | MFCD06202646 |
Formula : | C10H14O2 | Boiling Point : | 272.1°C at 760 mmHg |
Linear Structure Formula : | - | InChI Key : | N/A |
M.W : | 166.22 | Pubchem ID : | 250081 |
Synonyms : |
|
TPSA :Topological Polar Surface Area | 29.5 | H-Bond Acceptor Count : | 2 |
XLogP3 : | - | H-Bond Donor Count : | 1 |
SP3 : | 0.40 | Rotatable Bond Count : | 3 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
![]() |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | With hydrogen In methanol at 20℃; for 4.1 h; | General procedure: A mixture of 1a (196 mg, 1 mmol) and 1percentPd/Ni bimetallic catalyst9 (60 mg, 30 wt percent) in MeOH (10 mL) was stirred underH2 at room temperature and atmospheric pressure (on an atmosphericpressure hydrogenation apparatus) until the absorption of hydrogen ceased(3.5 h). After the catalyst was removed off by a magnetic stirring bar, thesolution was evaporated in a vaporator to give the product 2a |
81% | Stage #1: With sodium tetrahydroborate In methanol at 0 - 35℃; for 4 h; Stage #2: With hydrogenchloride; water In methanol |
Reference Example 110 (4-Isopropoxyphenyl)methanol With ice cooling, to a solution of 4-isopropoxybenzaldehyde (0.93 g, 5.6 mmol) in methanol (20 mL) was added a solution of sodium tetrahydroborate (0.32 g, 11 mmol) in methanol (10 mL), and the mixture was stirred at room temperature for 4 hours. The mixture was acidified by adding 2 N hydrochloric acid to the reaction solution, and extracted with diethyl ether. The extract was washed with water, and then concentrated under reduced pressure. The residue was purified with silica gel column chromatography (hexane/ethyl acetate = 7: 3) to give the title compound (0.76 g, yield 81percent) as an oily matter. 1H NMR: 1.33 (6H, d, J=6.1), 4.55 (1H, quintet, J=6.1), 4.61 (2H, s), 6.85-6.91 (2H, m), 7.25-7.30 (2H, m). |