Home Cart Sign in  
Chemical Structure| 834-28-6 Chemical Structure| 834-28-6
Chemical Structure| 834-28-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Phenformin HCl is an AMPK activator which can increase the phosphorylation and activation of AMPKalpha1 and AMPKalpha2.

Synonyms: Phenethylbiguanide hydrochloride; Phenformin (hydrochloride); Phenethylbiguanide HCl

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Phenformin HCl

CAS No. :834-28-6
Formula : C10H16ClN5
M.W : 241.72
SMILES Code : N=C(NCCC1=CC=CC=C1)NC(N)=N.[H]Cl
Synonyms :
Phenethylbiguanide hydrochloride; Phenformin (hydrochloride); Phenethylbiguanide HCl
MDL No. :MFCD00035039

Safety of Phenformin HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of Phenformin HCl

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 834-28-6 ]

[ 834-28-6 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 120-57-0 ]
  • [ 834-28-6 ]
  • 6-benzo[1,3]dioxol-5-yl-1-phenethyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine [ No CAS ]
  • 2
  • [ 834-28-6 ]
  • C10H12N8O3 [ No CAS ]
  • 4
  • chromium chloride [ No CAS ]
  • [ 834-28-6 ]
  • C30H45CrN15(3+)*3Cl(1-) [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; In ethanol; water; at 30℃; for 0.5h; 1) Adding <strong>[834-28-6]<strong>[834-28-6]phenformin</strong> hydrochloride</strong> and sodium hydroxide at a molar ratio of 1:1 to a mixture of water and ethanol in a 1:1 volume ratio.Stirring and dissolving at a temperature of 30°C;The water and ethanol mixture is added in an amount of 20 times the total mass of <strong>[834-28-6]<strong>[834-28-6]phenformin</strong> hydrochloride</strong> and sodium hydroxide;2) Dissolve chromium trichloride in water to obtain a chromium trichloride solution with a concentration of 0.5 mol/L.And a solution of chromium trichloride was slowly added dropwise to the solution prepared in step 1) at a rate of 50 drops per minute,The molar ratio of the amount of chromium trichloride used in this step to the amount of <strong>[834-28-6]<strong>[834-28-6]phenformin</strong> hydrochloride</strong> used in step 1) is:1:3; stirring at 30°C for 30 minutes to stop the reaction,Let stand for 2h, filter, wash the solid with distilled water and ether, then dry naturally.The resulting red solid is the <strong>[834-28-6]phenformin</strong> Cr (III) complex.
  • 5
  • [ 1292280-40-0 ]
  • [ 834-28-6 ]
  • [(η5-biphenyltetramethylcyclopentadienyl)Ir(phenformin)Cl]Cl [ No CAS ]
  • 6
  • C16H9Cl2N3O3 [ No CAS ]
  • [ 834-28-6 ]
  • 6-(3-(2,4-dichlorophenyl)-1-(4-nitrophenyl)-1H-pyrazol-4-yl)-3,6-dihydro-N<SUP>2</SUP>-phenethyl-1,3,5-triazine-2,4-diamine [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With acetic acid; at 120℃; General procedure: Synthesized intermediate compounds (1 mmol) and Moroxydine hydrochloride, metformin hydrochloride or <strong>[834-28-6]<strong>[834-28-6]phenformin</strong> hydrochloride</strong> (1 mmol) were refluxed in glacial acetic acid (10 mL) at 120°C for 4?6 h. The whole processes of the reactions were traced by TLC, then removed solvent under reduced pressure. The crude products were purified by column chromatography (dichloromethane : methanol = 20 : 1).
  • 7
  • [ 423-39-2 ]
  • [ 834-28-6 ]
  • [ 1869-76-7 ]
  • 8
  • C17H10Cl3NO2 [ No CAS ]
  • [ 834-28-6 ]
  • 3-[4-amino-6-(phenethylamino)-2,5-dihydro-1,3,5-triazin-2-yl]-6-[(2,4-dichlorobenzyl)oxy]quinolin-2-ol [ No CAS ]
  • 9
  • C17H10Cl3NO2 [ No CAS ]
  • [ 834-28-6 ]
  • 6-[(2,6-dichlorobenzyl)oxy]-3-{4-hydroxy-6-[(2-phenylethyl)amino]-2,5-dihydro-1,3,5-triazin-2-yl}quinolin-2-ol [ No CAS ]
  • 10
  • [ 1447374-25-5 ]
  • [ 834-28-6 ]
  • 3-[4-amino-6-(phenethylamino)-2,5-dihydro-1,3,5-triazin-2-yl]-6-[(3-chlorobenzyl)oxy]quinolin-2-ol [ No CAS ]
 

Historical Records

Categories