[ CAS No. 847902-56-1 ] {[proInfo.proName]}

Name: 847902-56-1|5-Fluoro-2-nitropyridin-3-ol|95%
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SKU: A127783
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DV 2D 3D

3d Animation Molecule Structure of 847902-56-1

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Quality Control of [ 847902-56-1 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 847902-56-1 ]

SDS Specification

Alternatived Products of [ 847902-56-1 ]

Product Details of [ 847902-56-1 ]

CAS No. :	847902-56-1	MDL No. :	MFCD11878539
Formula :	C₅H₃FN₂O₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	XCYLKKXQKCXJAE-UHFFFAOYSA-N
M.W :	158.09	Pubchem ID :	67387800
Synonyms :

Calculated chemistry of [ 847902-56-1 ] Expand+

Physicochemical Properties

Num. heavy atoms :	11
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.0
Num. rotatable bonds :	1
Num. H-bond acceptors :	5.0
Num. H-bond donors :	1.0
Molar Refractivity :	35.04
TPSA :	78.94 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	No
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.33 cm/s

Lipophilicity

Log Po/w (iLOGP) :	0.74
Log Po/w (XLOGP3) :	1.31
Log Po/w (WLOGP) :	1.25
Log Po/w (MLOGP) :	-0.07
Log Po/w (SILICOS-IT) :	-0.75
Consensus Log Po/w :	0.5

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-1.98
Solubility :	1.64 mg/ml ; 0.0104 mol/l
Class :	Very soluble
Log S (Ali) :	-2.57
Solubility :	0.427 mg/ml ; 0.0027 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-1.1
Solubility :	12.6 mg/ml ; 0.0798 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	2.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	2.2

Safety of [ 847902-56-1 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 847902-56-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 847902-56-1 ]

[ 847902-56-1 ] Synthesis Path-Downstream 1~10

1
[ 847902-56-1 ]
[ 75-03-6 ]
[ 59455-37-7 ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; In acetonitrile; at 100℃; for 5.0h;	A mixture of <strong>[847902-56-1]5-fluoro-2-nitropyridin-3-ol</strong> (0.35 g, 2.2 mmol), ethyl iodide (1.4 mL, 18 MMOL), K2CO3 (3.0 g, 22 mmol), and acetonitrile (40 mL) was heated at 100 C under N2. After 5 h, the acetonitrile was removed in vacuo, and the residue was partitioned between water (200 ML) and chloroform (100 ML). The aqueous layer was extracted with chloroform (100 mL x 2), and the combined organic extracts were dried (MGS04), filtered, and concentrated to give 0.19 g of 3-ethoxy-5- FLUORO-2-NITROPYRIDINE. 1H NMR (CDC13, 500 MHz) 8 7.93 (dd, 2H), 7.22 (dd, 1H), 4.20 (q, 2H), 1.51 (t, 3H).

Reference： [1]Patent: WO2005/21529,2005,A1 .Location in patent: Page/Page column 58

2
[ 209328-55-2 ]
[ 847902-56-1 ]

Yield	Reaction Conditions	Operation in experiment
81%	With sulfuric acid; nitric acid; at 0 - 20℃;	Example 10A 5-Fluoro-2-nitropyridin-3-ol With ice cooling, 5 g of 5-fluoropyridin-3-ol (44 mmol, 1 equivalent) were dissolved in 43 ml of concentrated sulphuric acid, and 2.8 ml of concentrated nitric acid were added at 0 C. over a period of 5 min. The reaction was warmed to RT and stirred overnight. The mixture was added to 100 g of ice and stirred for 30 min. The solid formed was filtered off and dried under reduced pressure. This gave 5.6 g (81% of theory) of the title compound which was used without further purification for the next reaction. LC-MS (Method 1): Rt=0.45 min MS (ESneg): m/z=156.9 (M-H)- 1H NMR (400 MHz, DMSO-d6): delta=7.5 (dd, 1H); 8.08 (d, 1H); 12.2 (br. s, 1H).
81%	With sulfuric acid; nitric acid; at 0 - 20℃;	Example 7A 5-Fluoro-2-nitropyridin-3-ol With ice cooling, 5 g of 5-fluoropyridin-3-ol (44 mmol, 1 equivalent) were dissolved in 43 ml of concentrated sulphuric acid, and, at 0 C., 2.8 ml of concentrated nitric acid were added over a period of 5 min. The reaction was warmed to RT, and stirring was continued overnight. The mixture was added to 100 g of ice and stirred for 30 min. The solid obtained was filtered off and dried under reduced pressure. This gave 5.6 g (81% of theory) of the title compound, which were used without further purification for the next reaction. LC-MS (Method 2): Rt=0.45 min MS (ESneg): m/z=156.9 (M-H)- 1H NMR (400 MHz, DMSO-d6): delta=7.5 (dd, 1H); 8.08 (d, 1H); 12.2 (br. s, 1H).
81%	With sulfuric acid; nitric acid; at 0 - 20℃;	With ice cooling, 5 g of 5-fluoropyridin-3-ol (44mmol, 1 equivalent) were dissolved in 43 ml of concentratedsulphuric acid, and 2.8 ml of concentrated nitric acid wereadded at 00 C. over 5 mm. The reaction was warmed to RTand stirred overnight. The mixture was poured onto 100 g ofice and stirred for 30 mm. The crystals were filtered off withsuction and dried under reduced pressure. This gave 5.6 g(81% of theory) of the title compound which was usedwithout thrther purification for the next reaction.10347] LC-MS (Method 2): R=0.45 mm10348] MS (ESneg): mlz=156.9 (M-H)10349] ?H-NMR (400 MHz, DMSO-d5): oe=7.5 (dd, 1H);8.08 (d, 1H); 12.2 (br. s, 1H).

Nitric acid (0.25 mL, 5.0 mmol) was added over 1 min to a solution of 5-fluoropyridin-3-ol (0.25 g, 2.2 mmol) and sulfuric acid (3 mL) at 70 C. After 20 min, a second aliquot (0.25 mL) of nitric acid was added over 1 min. After an additional 40 min, the reaction was cooled to 0 C. Water (25 mL) was added followed by slow addition of 10 N NAOH (13 mL) at 0 C. The solution was neutralized with 1 N HCI and concentrated to give 5-FLUORO-2-NITROPYRIDIN-3-OL. MS (ESI): 158. 8 (M+H).

Reference： [1]Patent: US2014/128386,2014,A1 .Location in patent: Paragraph 1026; 1027; 1028; 1029; 1030
[2]Patent: US2014/128372,2014,A1 .Location in patent: Paragraph 0389; 0390; 0391; 0392; 0392; 0393
[3]Patent: US2016/362408,2016,A1 .Location in patent: Paragraph 0345; 0346; 0347; 0348; 0349
[4]Patent: WO2005/21529,2005,A1 .Location in patent: Page/Page column 58

3
[ 847902-56-1 ]
2-amino-5-fluoropyridin-3-ol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
85%	With palladium 10% on activated carbon; hydrogen; In ethanol; under 760.051 Torr; for 16.0h;	Example 11A 2-Amino-5-fluoropyridin-3-ol 5.6 g of <strong>[847902-56-1]5-fluoro-2-nitropyridin-3-ol</strong> (Example 10A; 36 mmol) were dissolved in 2 l of ethanol, a catalytic amount of palladium on activated carbon (10%) was added and the mixture was hydrogenated under hydrogen standard pressure for 16 h. The mixture was filtered off through kieselguhr and the filtrate was concentrated (product batch 1). The residue was rinsed with methanol until the colour of the filtrate was no longer yellowish. The filtrate was concentrated, giving a second product batch. This gave a total of 4.26 g (85% of theory) of the title compound. LC-MS (Method 1): Rt=0.17 min MS (ESpos): m/z=128.9 (M+H)+ 1H NMR (400 MHz, DMSO-d6): delta=5.4 (br. s, 2H); 6.8 (dd, 1H); 7.4 (d, 1H).
85%	With palladium 10% on activated carbon; hydrogen; In ethanol; under 760.051 Torr; for 16.0h;	Example 8A 2-Amino-5-fluoropyridin-3-ol 5.6 g of <strong>[847902-56-1]5-fluoro-2-nitropyridin-3-ol</strong> (Example 7A; 36 mmol) were dissolved in 2 l of ethanol, a catalytic amount of palladium on activated carbon (10%) was added and the mixture was hydrogenated under standard hydrogen pressure for 16 h. The mixture was filtered off through silica gel and the filtrate was concentrated (product batch 1). The filter cake was rinsed with methanol until the colour of the filtrate was no longer yellowish. The filtrate was concentrated, giving a second product batch. This gave 4.26 g (85% of theory) of the title compound. LC-MS (Method 2): Rt=0.17 min MS (ESpos): m/z=128.9 (M+H)+ 1H NMR (400 MHz, DMSO-d6): delta=5.4 (br. s, 2H); 6.8 (dd, 1H); 7.4 (d, 1H).
85%	With palladium 10% on activated carbon; hydrogen; In ethanol; under 760.051 Torr; for 16.0h;	5.6 g of <strong>[847902-56-1]5-fluoro-2-nitropyridin-3-ol</strong> (Example 7A;36 mmol) were dissolved in 2 1 of ethanol, a catalytic amount of palladium on activated carbon (10%) was added and the mixture was hydrogenated under 1 atmosphere of hydrogen for 16 h. The mixture was filtered off through kieselguhr, and the filtrate was concentrated. The filter cake was rinsed with methanol until the filtrate no longer had a yellow colout The filtrate was concentrated, giving a second product batch. Atotal of 4.26 g (85% of theory) of the title compound wereobtained.10352] LC-MS (Method 2): R=0.17 mm10353] MS (ESpos): mlz=128.9 (M+H)10354] ?H-NMR (400 MHz, DMSO-d5): &5.4 (bt 5, 2H);6.8 (dd, 1H); 7.4 (d, 1H).

Reference： [1]Patent: US2014/128386,2014,A1 .Location in patent: Paragraph 1031; 1032; 1033; 1034; 1035
[2]Patent: US2014/128372,2014,A1 .Location in patent: Paragraph 0394; 0395; 0396; 0397; 0398
[3]Patent: US2016/362408,2016,A1 .Location in patent: Paragraph 0350; 0351; 0352; 0353; 0354

4
[ 847902-56-1 ]
[ 1609165-56-1 ]

Reference： [1]Patent: US2014/128386,2014,A1
[2]Patent: US2014/128372,2014,A1
[3]Patent: US2016/362408,2016,A1

5
[ 847902-56-1 ]
[ 1609165-57-2 ]

Reference： [1]Patent: US2014/128386,2014,A1
[2]Patent: US2014/128372,2014,A1
[3]Patent: US2016/362408,2016,A1

6
[ 847902-56-1 ]
[ 1609165-58-3 ]

Reference： [1]Patent: US2014/128386,2014,A1
[2]Patent: US2014/128372,2014,A1
[3]Patent: US2016/362408,2016,A1

7
[ 847902-56-1 ]
[ 1609341-55-0 ]

Reference： [1]Patent: US2014/128372,2014,A1

8
[ 847902-56-1 ]
tert-butyl {2-[({8-[(2,6-difluorobenzyl)oxy]-6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl}carbonyl)amino]-2-(3,4-difluorophenyl)ethyl}carbamate [ No CAS ]

Reference： [1]Patent: US2014/128372,2014,A1

9
[ 847902-56-1 ]
N-[2-amino-1-(3,4-difluorophenyl)ethyl]-8-[(2,6-difluorobenzyl)oxy]-6-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxamide [ No CAS ]

Reference： [1]Patent: US2014/128372,2014,A1

10
[ 847902-56-1 ]
8-[(2,6-difluorobenzyl)oxy]-N-(3,5-dimethyl-1H-pyrazol-4-yl)-6-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxamide [ No CAS ]

Reference： [1]Patent: US2016/362408,2016,A1

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Technical Information

• Add Hydrogen Cyanide to Aldehydes and Ketones to Produce Alcohols • Alcohol Syntheses from Aldehydes, Ketones and Organometallics • Alcohols are Weakly Basic • Alcohols as Acids • Alcohols Convert Acyl Chlorides into Esters • Alcohols from Haloalkanes by Acetate Substitution-Hydrolysis • Alcohols React with PX3 • Alcoholysis of Anhydrides • Aldehydes and Ketones Form Hemiacetals Reversibly • Aldol Addition • Alkene Hydration • Alkene Hydration • Alkyl Halide Occurrence • An Alkane are Prepared from an Haloalkane • Appel Reaction • Base-Catalyzed Hydration of α,β -Unsaturated Aldehydes and Ketones • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Carboxylic Acids React with Alcohols to Form Esters • Chichibabin Reaction • Chloroalkane Synthesis with SOCI2 • Chromium Reagents for Alcohol Oxidation • Chugaev Reaction • Claisen Condensations Produce β-Dicarbonyl Compounds • Claisen Condensations Produce β-Dicarbonyl Compounds • Convert Esters into Aldehydes Using a Milder Reducing Agent • Convert Haloalkanes into Alcohols by SN2 • Corey-Kim Oxidation • Decarboxylation of 3-Ketoacids Yields Ketones • Decomposition of Lithium Aluminum Hydride by Protic Solvents • Dess-Martin Oxidation • Esters Are Reduced by LiAlH4 to Give Alcohols • Esters Hydrolyze to Carboxylic Acids and Alcohols • Ether Synthesis by Oxymercuration-Demercuration • Ethers Synthesis from Alcohols with Strong Acids • Friedel-Crafts Alkylation of Benzene with Haloalkanes • Friedel-Crafts Alkylations Using Alcohols • Geminal Diols and Acetals Can Be Hydrolyzed to Carbonyl Compounds • Grignard Reagents Transform Esters into Alcohols • Grignard Reagents Transform Esters into Alcohols • Haloalcohol Formation from an Alkene Through Electrophilic Addition • Halogen and Alcohols Add to Alkenes by Electrophilic Attack • Halogen and Alcohols Add to Alkenes by Electrophilic Attack • Hantzsch Pyridine Synthesis • Hemiaminal Formation from Amines and Aldehydes or Ketones • Hemiaminal Formation from Amines and Aldehydes or Ketones • HIO4 Oxidatively Degrades Vicinal Diols to Give Carbonyl Derivatives • Hydration of the Carbonyl Group • Hydride Reductions • Hydride Reductions of Aldehydes and Ketones to Alcohols • Hydride Reductions of Aldehydes and Ketones to Alcohols • Hydroboration-Oxidation • Hydroboration-Oxidation • Hydrolysis of Haloalkanes • Jones Oxidation • Ketones Undergo Mixed Claisen Reactions to Form β-Dicarbonyl Compounds • Martin's Sulfurane Dehydrating Reagent • Mitsunobu Reaction • Moffatt Oxidation • Osmium Tetroxide Reacts with Alkenes to Give Vicinal Diols • Osmium TetroxideReacts with Alkenes to Give Vicinal Diols • Oxidation of Alcohols by DMSO • Oxymercuration-Demercuration • Preparation of Alcohols • Preparation of Alkenes by Dehydration of Alcohols • Preparation of Alkenes by Dehydration of Alcohols • Preparation of Alkoxides with Alkyllithium • Preparation of Amines • Primary Ether Cleavage with Strong Nucleophilic Acids • Pyridines React with Grignard or Organolithium Reagents • Reactions of Alcohols • Reactions with Organometallic Reagents • Reduction of an Ester to an Alcohol • Reduction of Carboxylic Acids by LiAlH4 • Reduction of Carboxylic Acids by Lithium Aluminum Hydride • Reduction of Carboxylic Acids by Lithium Aluminum Hydride • Ring Opening of an Oxacyclopropane by Lithium Aluminum Hydride • Ritter Reaction • Sharpless Olefin Synthesis • Swern Oxidation • Synthesis of Alcohols from Tertiary Ethers • Synthesis of an Alkyl Sulfonate • The Nucleophilic Opening of Oxacyclopropanes • Thiazolium Salt Catalysis in Aldehyde Coupling • Thiazolium Salts Catalyze Aldehyde Coupling • Thiazolium Salts Catalyze Aldehyde Coupling • Transesterification • Use 1,3-dithiane to Prepare of α-Hydroxyketones • Vicinal Anti Dihydroxylation of Alkenes • Williamson Ether Syntheses

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Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
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Prevention
Code	Phrase
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Response
Code	Phrase
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P320
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P321
P322
P330	Rinse mouth.
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P342	If experiencing respiratory symptoms:
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P378
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P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
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P406	Store in corrosive resistant/ container with a resistant inner liner.
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P411
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P413
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P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	Inquiry	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ item.pr_usastock ]}		{[ item.pr_chinastock ]}	{[ item.pr_remark ]}

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 847902-56-1 ] {[proInfo.proName]}

Quality Control of [ 847902-56-1 ]

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Calculated chemistry of [ 847902-56-1 ] Expand+

Physicochemical Properties

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Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

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Application In Synthesis of [ 847902-56-1 ]

[ 847902-56-1 ] Synthesis Path-Downstream 1~10

Technical Information

Related Functional Groups of [ 847902-56-1 ]

Fluorinated Building Blocks

Alcohols

Nitroes

Related Parent Nucleus of [ 847902-56-1 ]

Pyridines

Precautionary Statements-General

Prevention

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Storage

Disposal

Physical hazards

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Inquiry

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[ 847902-56-1 ]

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[ 847902-56-1 ]