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Chemical Structure| 848141-12-8 Chemical Structure| 848141-12-8

Structure of 848141-12-8

Chemical Structure| 848141-12-8

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Product Details of [ 848141-12-8 ]

CAS No. :848141-12-8
Formula : C7H6N2S
M.W : 150.20
SMILES Code : N#CC1=NC=C(SC)C=C1
MDL No. :MFCD24219128

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Application In Synthesis of [ 848141-12-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 848141-12-8 ]

[ 848141-12-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 327056-62-2 ]
  • [ 5188-07-8 ]
  • [ 848141-12-8 ]
YieldReaction ConditionsOperation in experiment
In N,N-dimethyl-formamide; at 0 - 20℃; for 2.5h; To a mixture of <strong>[327056-62-2]5-fluoropicolinonitrile</strong> (10 g, (0673) 81.9 mmol) in DMF (150 mL) was added sodium methanethiolate (6.89 g, 98.3 mmol) at 0 C. The mixture was stirred at 0 C for 0.5 h and then warmed to 20 C. The mixture was stirred at 20 C for 2 h. The mixture was poured into saturated NEECl (2 L) and then extracted with EtOAc. The organic layers were concentrated to give 5-(methylthio)-picolinonitrile (8.5 g, 51.0 mmol, 62.27% yield, 90.12% purity) and used without further purification
 

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