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Chemical Structure| 850406-38-1 Chemical Structure| 850406-38-1

Structure of 850406-38-1

Chemical Structure| 850406-38-1

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Product Details of [ 850406-38-1 ]

CAS No. :850406-38-1
Formula : C7H7N3O
M.W : 149.15
SMILES Code : O=C1C2=NC(C)=CN2C=CN1
MDL No. :N/A

Safety of [ 850406-38-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 850406-38-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 850406-38-1 ]

[ 850406-38-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 85333-43-3 ]
  • [ 850406-38-1 ]
YieldReaction ConditionsOperation in experiment
89% A mixture of 8-chloro-2-methylimidazo [1, 2-a] pyrazine (Compound IIa in Scheme 1, 2.5 g, 15 mmol) and conc. HC1 (1.5 mL, 1.2 eq. , 18 mmol) in water (20 mL) was refluxed for 3 h. The cooled reaction mixture was concentrated in vacuo and the residual solid was extracted with hot ethanol (4 x 100 mL). The combined ethanolic filtrates were treated with KHC03 (1. 8 g, 1.2 eq. , 18 mmol), the resultant insoluble material was filtered and the filtrate was concentrated in vacuo to provide 2.0 g (89% yield) of the title compound. 1H NMR (DMSO-d6) S 12.15 (br s, 1H), 7.90 (s, 1H), 7. 68 (d, J 5. 5 Hz, 1H), 7.20 (t, J5. 5 Hz, 1H), 2.38 (s, 3H)
 

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