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Chemical Structure| 851211-79-5 Chemical Structure| 851211-79-5

Structure of 851211-79-5

Chemical Structure| 851211-79-5

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Product Details of [ 851211-79-5 ]

CAS No. :851211-79-5
Formula : C10H11N3O
M.W : 189.21
SMILES Code : O=C(C1=CC2=C(N(C)C=C2)C=C1)NN
MDL No. :MFCD11978046

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Application In Synthesis of [ 851211-79-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 851211-79-5 ]

[ 851211-79-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 128742-76-7 ]
  • [ 851211-79-5 ]
YieldReaction ConditionsOperation in experiment
24% With hydrazine hydrate; In ethanol; for 18h;Heating; Preparation of 1-methyl 1H-indole-5-carboxylic acid hydrazide To 1.0 g (5.3 mmol) of the 1-methyl 1H-benzimidazole 5-carboxylic acid methyl ester, dissolved in 20 ml of ethanol, 20 ml (400mml) of hydrated hydrazine (100%) are added. The solution is heated for 18 hours After concentration, the concentrate is dissolved in water, alkanized with ammoniac (20%) to basic pH and filtrated the concentrate is then washed with water and vacuum desiccated. 240 mg of a white powder is obtained (R=24%). RMN 1H (DMSO-d6, 300 MHz) delta : 3.79 (s, 3H), 4.43 (bs,2H), 6.49 (d, J=2.9 Hz, 1H), 7.38 (d, J=3.1 Hz,1H), 7.44 (d, J=8.6 Hz, 1H), 7.66 (dd, J=8.6 Hz, J=1.5 Hz, 1H), 8.08(d, J= 1.5 Hz,1H), 9.60 (bs, 1H).
 

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