Alternatived Products of [ 855930-17-5 ]
Product Details of [ 855930-17-5 ]
CAS No. : | 855930-17-5 |
MDL No. : | MFCD30529794 |
Formula : |
C12H9BrN2O3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
309.12
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 855930-17-5 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 855930-17-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 855930-17-5 ]
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[ 71590-31-3 ]
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[ 855930-17-5 ]
- 2
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[ 855930-17-5 ]
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[ 1241377-74-1 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 2 steps
1: hydrogenchloride; methanol / 6 h / 75 °C
2: water; iron / ammonium chloride / tetrahydrofuran / 3 h / 60 °C |
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Multi-step reaction with 2 steps
1: hydrogenchloride; water / methanol / 6 h / 75 °C
2: ammonium chloride; iron / water; tetrahydrofuran / 3 h / 60 °C |
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Multi-step reaction with 2 steps
1: hydrogenchloride / methanol; water / 6 h / 75 °C
2: iron; ammonium chloride / water; tetrahydrofuran / 3 h / 60 °C |
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Multi-step reaction with 2 steps
1: hydrogenchloride / tetrahydrofuran / 7 h / 80 °C
2: sodium carbonate; sodium dithionite / 1,4-dioxane / 5 h / 0 - 20 °C |
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Multi-step reaction with 2 steps
1: hydrogenchloride / methanol; water / 6 h / 75 °C
2: iron; ammonium chloride / tetrahydrofuran; water / 3 h / 60 °C |
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Reference:
[1]Current Patent Assignee: MERCK & CO INC - WO2011/66241, 2011, A1
[2]Current Patent Assignee: MERCK & CO INC - EP2545060, 2015, B1
[3]Yu, Wensheng; Vibulbhan, Bancha; Rosenblum, Stuart B.; Martin, Gregory S.; Vellekoop, A. Samuel; Holst, Christian L.; Coburn, Craig A.; Wong, Michael; Selyutin, Oleg; Ji, Tao; Zhong, Bin; Hu, Bin; Chen, Lei; Dwyer, Michael P.; Jiang, Yueheng; Nair, Anilkumar G.; Tong, Ling; Zeng, Qingbei; Agrawal, Sony; Carr, Donna; Rokosz, Laura; Liu, Rong; Curry, Stephanie; McMonagle, Patricia; Ingravallo, Paul; Lahser, Fred; Asante-Appiah, Ernest; Fells, James; Kozlowski, Joseph A.
[Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3793 - 3799]
[4]Current Patent Assignee: SHENZHEN DONGYANGGUANG INDUSTRIAL DEVELOPMENT CO LTD - WO2016/141890, 2016, A1
[5]Current Patent Assignee: MERCK & CO INC - WO2011/87740, 2011, A1
- 3
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[ 7499-66-3 ]
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[ 855930-17-5 ]
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[ 591253-73-5 ]
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[ 855930-17-5 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 2 steps
1: triethylamine; dmap / dichloromethane / 3 h / 20 °C / Industrial scale
2: nitric acid / acetic anhydride; acetic acid / 11 h / 35 - 45 °C / Industrial scale |
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