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Chemical Structure| 859297-12-4 Chemical Structure| 859297-12-4

Structure of 859297-12-4

Chemical Structure| 859297-12-4

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Product Details of [ 859297-12-4 ]

CAS No. :859297-12-4
Formula : C8H9N3
M.W : 147.18
SMILES Code : N#CC1=NC(C)=C(C)N=C1C
MDL No. :MFCD26408036

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Application In Synthesis of [ 859297-12-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 859297-12-4 ]

[ 859297-12-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 186534-02-1 ]
  • [ 859297-12-4 ]
YieldReaction ConditionsOperation in experiment
65% With formic acid; hydroxylamine hydrochloride; sodium formate; at 120℃; 5.5 g (36.7 mmol) of compound 1a-4The sample was dissolved in 30 ml of formic acid.Weigh 3.2g (45.9mmol)Hydroxylamine hydrochloride was added, followed by 3.13 g (45.9 mmol)Sodium formate, miscible, 120 C oil bath reaction reflux overnight.The pH of the reaction mixture was adjusted to 10 with a saturated aqueous sodium hydroxide solution and extracted with dichloromethane (30 ml*5 times). 100-200 mesh silica gel sample, dry sample column chromatography:Mobile phase EA: PE (1:5), TLC monitors the fraction of the effluent fraction,The compound 1a-5 fraction was collected. Combine the same fraction and distill dry,White solidCompound 1a-5, yield 65%.
 

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