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Chemical Structure| 86799-26-0 Chemical Structure| 86799-26-0

Structure of 86799-26-0

Chemical Structure| 86799-26-0

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Product Details of [ 86799-26-0 ]

CAS No. :86799-26-0
Formula : C10H10N4O
M.W : 202.22
SMILES Code : NNC1=NC(=CC(=O)N1)C1=CC=CC=C1
MDL No. :MFCD00847527

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Application In Synthesis of [ 86799-26-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 86799-26-0 ]

[ 86799-26-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 36822-11-4 ]
  • [ 86799-26-0 ]
YieldReaction ConditionsOperation in experiment
With hydrazine hydrate; for 4.0h;Reflux; General procedure: A mixture of 6-(4-chlorophenyl)-3,4-dihydro-2-thiopyrimidin-4(3H)-one 8b (500mg, 2.1mmol) and hydrazine monohydrate (7.15mL, 7.36g, 0.15mol) was stirred at reflux for 4h. Afterwards, hydrazine was evaporated under reduced pressure. The residue was then triturated with water for 30min. The obtained precipitate was filtered off and subsequently washed with water to give a white powder used in the next step without further purification. 1H NMR (400MHz, DMSO-d6) delta ppm 6.11 (s, 1H, CH-pyrimidine ring), 7.49-7.51 (d, 2H, Ar), 7.98-8.01 (d, 2H, Ar), 8.57 (s, 1H, NH)
 

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