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Chemical Structure| 874792-18-4 Chemical Structure| 874792-18-4

Structure of 874792-18-4

Chemical Structure| 874792-18-4

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Product Details of [ 874792-18-4 ]

CAS No. :874792-18-4
Formula : C10H8BrN3O2
M.W : 282.09
SMILES Code : O=C(C1=C(O)C2=CC(Br)=CC=C2N=C1)NN
MDL No. :MFCD04036174

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Application In Synthesis of [ 874792-18-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 874792-18-4 ]

[ 874792-18-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 122794-99-4 ]
  • [ 874792-18-4 ]
YieldReaction ConditionsOperation in experiment
With hydrazine hydrate; In ethanol; for 4.5h;Reflux; General procedure: Substituted-1,4-dihydro-4-oxoquinoline-3-carboxylic acid ethyl ester 4 (0.01 mol) wasrefluxed for 12 h with hydrazine monohydrate (0.01mol) in absolute ethanol ( 9 mL) to give substituted-4-oxo-1,4-dihydroquinoline-3-carbohydrazide 5.The excess solvent was evaporated off and theresulting mixture was poured into crushed ice. Thesolid separated was filter on sintered funnel,washed with water and dried. The crude solid waspurified by recrystallized from Dioxane: ethanol togive 5 as white solid. Purity of the compound waschecked on silica gel TLC plates. TLC was run inchloroform-methanol (9:1) as eluent.
 

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