Alternatived Products of [ 885520-74-1 ]
Product Details of [ 885520-74-1 ]
CAS No. : | 885520-74-1 |
MDL No. : | MFCD07781464 |
Formula : |
C8H9N3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
147.18
|
Pubchem ID : | - |
Synonyms : |
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Safety of [ 885520-74-1 ]
Application In Synthesis of [ 885520-74-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 885520-74-1 ]
- 1
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[ 885520-77-4 ]
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[ 885520-74-1 ]
Yield | Reaction Conditions | Operation in experiment |
|
With iron; ammonium chloride; In ethanol; for 1.0h;Reflux; |
Second Step [Show Image] To an aqueous 80% ethanol solution (75 mL) of the product (0.80 g, 4.52 mmol) of the first step, ammonium chloride (0.12 g, 2.26 mmol) and iron (2.56 g, 45.2 mmol) were added, followed by reflux for one hour. The reaction mixture was cooled to room temperature and insoluble substances were filtered through cerite, followed by washing in turn with ethanol and ethyl acetate. The filtrate was concentrated under reduced pressure and water was added to the resulting residue, and then the precipitated solid was collected by filtration to obtain 0.43 g of 6-amino-4-methylindazole. 1H-NMR (500 MHz, DMSO-d6) d: 2.37 (s, 3H), 5.09 (s, 2H), 6.25 (s, 1H), 6.31 (s, 1H), 7.74 (s, 1H), 12.19 (s, 1H). |