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Chemical Structure| 885951-26-8 Chemical Structure| 885951-26-8

Structure of 885951-26-8

Chemical Structure| 885951-26-8

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Product Details of [ 885951-26-8 ]

CAS No. :885951-26-8
Formula : C13H16N2O
M.W : 216.28
SMILES Code : OC1=NC2=CC=CC=C2C(CNC(C)C)=C1

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Application In Synthesis of [ 885951-26-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 885951-26-8 ]

[ 885951-26-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4876-10-2 ]
  • [ 75-31-0 ]
  • [ 885951-26-8 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20℃; Step 1: 4-[(Isopropylamino)methyl]quinolin-2(1H)-one Propan-2-amine (7.47 g, 126.61 mmol) was added to a solution of <strong>[4876-10-2]4-(bromomethyl)quinolin-2(1H)-one</strong> (1 g, 4.22 mmol) in DMF (100 mL), followed by K2CO3 (590 mg, 4.28 mmol). The reaction mixture was stirred overnight at 0° C. in a H2O/ice bath then at RT. The reaction mixture was concentrated and washed with acetone (3*150 mL) to afford 1.1 g (crude) of 4-((isopropylamino)methyl) quinolin-2(1H)-one as a white solid.
 

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