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Chemical Structure| 89418-40-6 Chemical Structure| 89418-40-6

Structure of 89418-40-6

Chemical Structure| 89418-40-6

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Product Details of [ 89418-40-6 ]

CAS No. :89418-40-6
Formula : C6H6N4S
M.W : 166.20
SMILES Code : CC1=NN2C(S)=NN=C2C=C1
MDL No. :MFCD23725584

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Application In Synthesis of [ 89418-40-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 89418-40-6 ]

[ 89418-40-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 75-15-0 ]
  • [ 38956-79-5 ]
  • [ 89418-40-6 ]
YieldReaction ConditionsOperation in experiment
85% With potassium hydroxide; In methanol; at 0 - 20℃;Heating / reflux; Step 2: 6-Methyl-[l,2,4]triazoIo[4,3-b]pyridazine-3-thiol; [0373] To a solution of KOH (1 1.3 g, 0.202 mol) in methanol (100 mL) was added (6- methyl-pyridazin-3-yl)-hydrazine (25 g, 0.202 mol) at room temperature. The reaction mixture was placed in an ice-water bath and carbon disulfide (98 mL, 1.61 mol) was slowly added. The resultant yellow solution was heated to reflux overnight before removal of solvent. The yellow residue was acidified with 2 N aqueous HCl to pH~4, filtered, and washed with water. Upon drying 33 g of 6-methyl-[l, 2,4]triazolo [4,3 -b]pyridazine-3 -thiol was obtained as a yellow powder (85% yield): 1HNMR (DUSO-d6): delta 2.5 (s, 3H), 7.28 (d, IH), 8.05 (d, IH), 14.66 (br s, IH); MS (m/z) 167 [M+H+]+.
 

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