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Chemical Structure| 904929-05-1 Chemical Structure| 904929-05-1

Structure of 904929-05-1

Chemical Structure| 904929-05-1

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Product Details of [ 904929-05-1 ]

CAS No. :904929-05-1
Formula : C12H14N2O4
M.W : 250.25
SMILES Code : O=C(OCC)CC1CCC2=CC([N+]([O-])=O)=CN=C21
MDL No. :MFCD16293375

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Application In Synthesis of [ 904929-05-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 904929-05-1 ]

[ 904929-05-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 20826-94-2 ]
  • [ 14150-94-8 ]
  • [ 904929-05-1 ]
YieldReaction ConditionsOperation in experiment
With ammonia; In methanol;Heating / reflux; Intermediate 5-1A mixture of l-methyl-3, 5-dinitro-2-pyridone (11.7 g, 59 mmol) and ethyl cyclopentanoneacetate (10 g, 59 mmol) in 2 M NH3MeOH (300 niL) was refluxed overnight and then cooled to room temperature. Methanol was removed in vacuo and the residue was partitioned between EtOAc (200 mL) and water (400 mL). The aqueous layer was further extracted with EtOAc (2 x 150 mL). The organic layers were combined, washed with brine (150 mL), dried over Na2SO4 and concentrated in vacuo. The residue was purified by flash chromatography (eluting with a gradient of 0 to 20% EtOAc/hexanes) to give pure product as light yellow oil. LC-MS for C12H15N2O4 [M+H+] : calculated 251.1, found 251.2. EPO <DP n="22"/>
 

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