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Chemical Structure| 90731-57-0 Chemical Structure| 90731-57-0

Structure of 90731-57-0

Chemical Structure| 90731-57-0

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Product Details of [ 90731-57-0 ]

CAS No. :90731-57-0
Formula : C15H21NO4
M.W : 279.33
SMILES Code : C[C@@H](C1=CC=CC=C1)[C@H](NC(OC(C)(C)C)=O)C(O)=O
MDL No. :MFCD00800584

Safety of [ 90731-57-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 90731-57-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90731-57-0 ]

[ 90731-57-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1421-65-4 ]
  • [ 90731-57-0 ]
  • [ 946089-54-9 ]
YieldReaction ConditionsOperation in experiment
Step i; A mixture of (2S,3S)-2-tert-butoxycarbonylamino-3-phenylbutyric acid (0.5Og, 1.79mmol) and (S)-2-(3,4-dihydroxyphenyl)-1-methoxycarbonylethylammonium chloride (0.443g, 1.79mmol) in dichloromethane (35mL) was stirred at 2O0C. Triethylamine (0.5OmL, 3.58mmol) was added, the reaction mixture was stirred for 1min and HBTU (0.679g, 1.79mmol) was added. Stirring was continued at 2O0C for 16h. Dimethylacetamide was added and stirring was continued for a further 16h. The reaction mixture was diluted with dichloromethane, washed with water, dried and evaporated in vacuo to give a yellow oil which was purified by flash column chromatography eluting with ethyl acetate/hexane (1 :2) to afford a colourless solid (0.23g).
 

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