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Chemical Structure| 913073-73-1 Chemical Structure| 913073-73-1

Structure of 913073-73-1

Chemical Structure| 913073-73-1

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Product Details of [ 913073-73-1 ]

CAS No. :913073-73-1
Formula : C17H25NO2Si
M.W : 303.47
SMILES Code : O=C(NCC1C=C(C#C[Si](C)(C)C)C=CC=1)OC(C)(C)C

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Application In Synthesis of [ 913073-73-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 913073-73-1 ]

[ 913073-73-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 171663-13-1 ]
  • [ 1066-54-2 ]
  • [ 913073-73-1 ]
YieldReaction ConditionsOperation in experiment
67% With triethylamine;bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 90℃; for 18.08h; Example 2.36: tert-butyl 4-(3-ethynylbenzyIammo)-3-hydroxy-l-phenylbutan-2- ylcarbamate:; [0280] To <strong>[171663-13-1]tert-butyl 3-bromobenzylcarbamate</strong> (220 mg, 1 mmol) in triethylamine (3 ml), trimethylsilyl acetylene (147mg, 1.5 mmol) was added followed by cuprous iodide (8mg, 0.04 mmol). After stirring for 5 min, dichloro bis (triphenylphosphine) palladium (II) (35 mg, 0.05 mmol) was added and the reaction mixture was heated at 9O0C for 18h. Then the reaction mixture was filtered, diluted with ethyl acetate and washed with water. Organic layer was dried, evaporated and the crude residue was purified by column chromatography to obtain tert-butyl 3-((trimethylsilyl)ethynyl)benzylcarbamate in 67% yield.
  • 2
  • [ 263351-43-5 ]
  • [ 1066-54-2 ]
  • [ 913073-73-1 ]
 

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