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Chemical Structure| 918485-28-6 Chemical Structure| 918485-28-6

Structure of 918485-28-6

Chemical Structure| 918485-28-6

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Product Details of [ 918485-28-6 ]

CAS No. :918485-28-6
Formula : C10H11N3O2
M.W : 205.21
SMILES Code : O=C(OCC)CN1N=CC2=CC=CN=C21

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Application In Synthesis of [ 918485-28-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 918485-28-6 ]

[ 918485-28-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 105-36-2 ]
  • [ 271-73-8 ]
  • [ 918485-28-6 ]
YieldReaction ConditionsOperation in experiment
87% General procedure: A mixture of <strong>[271-73-8]1H-<strong>[271-73-8]pyrazolo[3,4-b]pyridine</strong></strong> 2 (1 eq.) and K2CO3 (10 eq.) in DMF was stirred at 80 °C. After 30 min, excess Br(CH2)nCO2Et was added and the reaction mixture was stirred for 1 h at 80 °C. Upon cooling, the mixture was acidified with 10percent aqueous HCl solution and the aqueous layer was extracted with EtOAc. The combined organic extracts were washed with brine and dried over anhydrous MgSO4. After filtration, the solvent was removed in vacuum and the resulting oil was purified by column chromatography (1:1 ethyl ether:petroleum ether).
 

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