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Chemical Structure| 92145-32-9 Chemical Structure| 92145-32-9

Structure of 92145-32-9

Chemical Structure| 92145-32-9

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Product Details of [ 92145-32-9 ]

CAS No. :92145-32-9
Formula : C8H14O3
M.W : 158.20
SMILES Code : O=C(OCC)/C(C)=C/OCC
MDL No. :MFCD16619210
InChI Key :WZCHIWJCAAITIC-VOTSOKGWSA-N
Pubchem ID :12637823

Safety of [ 92145-32-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H227
Precautionary Statements:P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235

Application In Synthesis of [ 92145-32-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 92145-32-9 ]

[ 92145-32-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 92145-32-9 ]
  • [ 108290-86-4 ]
  • ethyl 3-methyl-2-oxo-1,2-dihydropyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
54% With caesium carbonate; In N,N-dimethyl-formamide; at 150℃; for 3h; A solution of ethyl 3-ethoxy-2-methylacrylate (1.896 g, 12 mmol), ethyl 2-amino- 1H-pyrrole-3-carboxylate (1.54 g, 10 mol) and Cs2CO3 (3.9 g, 12 mmol) in DMF (20 mL) was heated at 150 C for 3 h. The solvent was removed by concentration in vacuo and the residuewas purified by silica gel column (PE/EA: 2/1) to afford ethyl 3-methyl-2-oxo-1,2-dihydropyrrolo[1 ,2-ajpyrimidine-8-carboxylate (1.2 g, 54%) as a yellow solid. ?H NMR (400MHz, CDC13) 9.72 (s, 1H), 7.64 (d, J= 1.2 Hz, 1H), 7.27 (s, 1H), 6.69 (d, J 3.6 Hz, 1H), 6.58(d, J 3.2 Hz, 1H), 4.33 (q, J 7.2 Hz, 2H), 2.09 (s, 3H), 1.37 (t, J= 7.2 Hz, 3H). LC-MS m/z:221.0 [M+Hf?. LCMS: Purity (214 nm): 97%; tR= 1.49 mm.
 

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