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Chemical Structure| 927020-14-2 Chemical Structure| 927020-14-2

Structure of 927020-14-2

Chemical Structure| 927020-14-2

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Product Details of [ 927020-14-2 ]

CAS No. :927020-14-2
Formula : C15H18N2OS
M.W : 274.38
SMILES Code : COC1=CC=CC=C1C2=CSC(C3CCNCC3)=N2
MDL No. :MFCD17092470

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Application In Synthesis of [ 927020-14-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 927020-14-2 ]

[ 927020-14-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 214834-18-1 ]
  • [ 31949-21-0 ]
  • [ 927020-14-2 ]
YieldReaction ConditionsOperation in experiment
92% In ethanol; at 90℃; for 2h; A mixture of 150 mg 2-bromo-1-(2-methoxyphenyl)ethan-1 -one (655 pmol) and 160 mg tert- butyl 4-carbamothioylpiperidine-1 -carboxylate (655 pmol) in 2 ml. of ethanol were stirred for 2 h at 90C. The reaction mixture was cooled to room te mperature, the solvent was evaporated and the crude product was purified by RP-HPLC. The product was obtained in 92% yield (197 mg).1H NMR (400 MHz, DMSO-d6) d ppm 1.81 - 1 .97 (m, 2 H) 2.22 (br dd, 2 H) 3.02 (td, 2 H) 3.29 -3.45 (m, 3 H) 3.92 (s, 3 H) 7.04 (td, 1 H) 7.14 (dd, 1 H) 7.34 (ddd, 1 H) 7.99 (s, 1 H) 8.13 (dd, 1H).
 

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