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Chemical Structure| 929037-56-9 Chemical Structure| 929037-56-9

Structure of 929037-56-9

Chemical Structure| 929037-56-9

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Product Details of [ 929037-56-9 ]

CAS No. :929037-56-9
Formula : C13H15NO
M.W : 201.26
SMILES Code : O=C(CC1)N(CC2=CC=CC=C2)C31CC3

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Application In Synthesis of [ 929037-56-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 929037-56-9 ]

[ 929037-56-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2142-06-5 ]
  • [ 925-90-6 ]
  • (5E)-1-benzyl-5-ethylidenepyrrolidin-2-one [ No CAS ]
  • [ 929037-56-9 ]
  • 2
  • [ 2142-06-5 ]
  • [ 925-90-6 ]
  • [ 929037-56-9 ]
YieldReaction ConditionsOperation in experiment
25% To a cooled (0 C) mixture of l-benzylpyrrolidine-2,5-dione (114 g, 600 mmol) and Ti(Oi-Pr)4(170.5 g, 600 mmol) in dry THF (2000 mL) under argon atmosphere was added dropwise a 3.4M solution of ethylmagnesium bromide in THF (1200 mmol). The mixture was warmed to room temperature and stirred for 4 h. BF3.Et20 (170 g, 1200 mmol) was then added dropwise and the solution stirred for 6 h. The mixture was cooled (0 C) and 3N hydrochloric acid (500 mL) was added. The mixture was extracted twice with Et20, and the combined organic extracts washed with brine, dried and concentrated under reduced pressure to give 4- benzyl-4-azaspiro[2.4]heptan-5-one (30.2 g, 150 mmol, 25% yield).
 

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