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Chemical Structure| 93427-14-6 Chemical Structure| 93427-14-6

Structure of 93427-14-6

Chemical Structure| 93427-14-6

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Product Details of [ 93427-14-6 ]

CAS No. :93427-14-6
Formula : C8H7BrCl2
M.W : 253.95
SMILES Code : ClC1=CC(Cl)=CC(CCBr)=C1
MDL No. :MFCD20432741

Safety of [ 93427-14-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H315-H319-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 93427-14-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93427-14-6 ]

[ 93427-14-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93427-13-5 ]
  • [ 93427-14-6 ]
YieldReaction ConditionsOperation in experiment
94% With 1H-imidazole; bromine; triphenylphosphine; In dichloromethane; at 20.0℃; for 0.5h; Step 1. Preparation of bromide 2[129] Bromine (0.80 mL, 15.5 mmol) was added to a solution of triphenylphosphine (4.12 g, 15.7 mmol) and imidazole (1.07 g, 15.7 mmol) in CH2CI2 (52 mL) at O C and the mixture was allowed to warm to room temperature. A solution of <strong>[93427-13-5]2-(3,5-dichlorophenyl)ethanol</strong> (1, 2.5 g, 13.1 mmol) in CH2CI2 (13 mL) was added via cannula. After 30 min at room temperature, the mixture was filtered through celite, washing with excess CH2CI2. The filtrate was concentrated in vacuo. The crude residue was purified by chromatography on 120 g silica (hexanes → 20% EtOAc/hexanes, gradient) to afford 3.13 g (94%) of bromide 2.
 

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