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Chemical Structure| 93429-13-1 Chemical Structure| 93429-13-1

Structure of 93429-13-1

Chemical Structure| 93429-13-1

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Product Details of [ 93429-13-1 ]

CAS No. :93429-13-1
Formula : C13H18N2O4
M.W : 266.29
SMILES Code : O=[N+](C1=CC=C(OCCCN2CCOCC2)C=C1)[O-]

Safety of [ 93429-13-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 93429-13-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93429-13-1 ]

[ 93429-13-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 100-02-7 ]
  • [ 57616-74-7 ]
  • [ 93429-13-1 ]
YieldReaction ConditionsOperation in experiment
With caesium carbonate; In N,N-dimethyl-formamide; at 100℃; for 2.5h;Inert atmosphere; General procedure: In 100 mL flask, 4-nitrophenol (1.39 g, 10 mmol) was dissolved in 20 mL anhydro-DMF. Then 3-chloro-N,N-dimethylpropan-1-amine hydrochloride (1.57 g, 10 mmol) and Cs2CO3 (5.29 g, 15 mmol) were added to the solution. Under N2, the mixture was heated to 100 C, and was reacted for 2.5 h. The mixture was filtered, and the filtrate was poured to ice water (200 mL). The aqueous phase was extracted by EtOAc (30 mL × 3). The combined organic phase was washed by Na2CO3 (10 mL × 4), water (10 mL × 2), saturated sodium chloride (15 mL). The organic layer was dried over Na2SO4, filtered, and distilled under vacuum to give the crude product.
 

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