Home Cart Sign in  
Chemical Structure| 939999-60-7 Chemical Structure| 939999-60-7

Structure of 939999-60-7

Chemical Structure| 939999-60-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 939999-60-7 ]

CAS No. :939999-60-7
Formula : C8H6F4N2O
M.W : 222.14
SMILES Code : N=C(NO)C1=CC=C(F)C(C(F)(F)F)=C1

Safety of [ 939999-60-7 ]

Application In Synthesis of [ 939999-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 939999-60-7 ]

[ 939999-60-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67515-59-7 ]
  • [ 939999-60-7 ]
YieldReaction ConditionsOperation in experiment
With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 65℃; for 16h;pH 7.0; Preparation of BB7: 4-Fluoro-N-hydroxy-3-trifluoromethyl-benzamidine:BB7; To a solution of the <strong>[67515-59-7]4-fluoro-3-trifluoromethyl-benzonitrile</strong> (20.0 g, 105.8 mmol) in ethanol (400 mL) a solution of the NH2OH-HCl (8.0 g, 116.4 mmmol) which was adjusted to pH=7.0 by addition of NaOH in H20 (8 mL) was added. The mixture was stirred vigorously and heated to about 65 C for about 16 h. The analysis by TLC indicated the completion of the reaction; it was concentrated to remove the solvent. The residue was redissolved in DCM (200 mL) and washed with water, brine and dried over Na2S04, concentrated in vacuum to afford 4-Fluoro-N-hydroxy-3-trifluoromethyl-benzamidine (BB7) as pale-yellow solid. 1H NMR (400 MHz, DMSO) delta ppm 9.83 (1H, s), 8.00 - 7.98 (2H, m), 7.50 (1H, t) and 6.00 (2H, s).
 

Historical Records