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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 878385-84-3 Chemical Structure| 878385-84-3

Structure of AZD-5069
CAS No.: 878385-84-3

Chemical Structure| 878385-84-3

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AZD 5069 is a selective and reversible antagonist of CXCR2 that can inhibit CXCL8 binding to CXCR2 with pIC50 of 9.1.

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of AZD-5069

CAS No. :878385-84-3
Formula : C18H22F2N4O5S2
M.W : 476.52
SMILES Code : O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[C@H](C)[C@@H](O)CO)=C2)=O
MDL No. :MFCD19443645
InChI Key :QZECRCLSIGFCIO-RISCZKNCSA-N
Pubchem ID :56645576

Safety of AZD-5069

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H360
Precautionary Statements:P201-P202-P280-P308+P313-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of AZD-5069

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02499328 Advanced Solid Tumors & Metast... More >>atic Squamous Cell Carcinoma of the Head and Neck Less << Phase 1 Phase 2 Recruiting October 31, 2019 -
NCT01962935 Chronic Obstructive Pulmonary ... More >>Disease (COPD). Less << Phase 1 Completed - United Kingdom ... More >> Research Site London, United Kingdom Less <<
NCT01989520 Uncontrolled and Persistent As... More >>thma Less << Phase 1 Completed - United Kingdom ... More >> Research Site London, United Kingdom Less <<
NCT02583477 Metastatic Pancreatic Ductal A... More >>denocarcinoma Less << Phase 1 Phase 2 Completed - United States, New York ... More >> Research Site Rochester, New York, United States, 14642 United Kingdom Research Site Cambridge, United Kingdom, CB2 0QQ Research Site Glasgow, United Kingdom, G12 0YN Research Site London, United Kingdom, SE1 9RY Research Site London, United Kingdom, W12 0NN Research Site Manchester, United Kingdom, M20 4BX Research Site Wirral, United Kingdom, CH63 4JY Less <<
NCT01255592 Bronchiectasis ... More >> Lung Disease Respiratory Diseases Less << Phase 2 Completed - Czech Republic ... More >> Research Site Ostrava, Czech Republic Research Site Prague, Czech Republic Poland Research Site Krakow, Poland Research Site Lodz, Poland Research Site Warszawa, Poland United Kingdom Research Site Hull, East Yorkshire, United Kingdom Research Site Leicester, Leicestershire, United Kingdom Research Site Birmingham, Wstmid, United Kingdom Research Site Belfast, United Kingdom Research Site Bristol, United Kingdom Research Site Cambridge, United Kingdom Research Site London, United Kingdom Research Site Newcastle-upon-tyne, United Kingdom Research Site Salford, United Kingdom Research Site Wolverhampton, United Kingdom Less <<
NCT01233232 - Completed - -
NCT01255592 - Completed - -
NCT01890148 Asthma Phase 1 Completed - Germany ... More >> Research Site Grosshansdorf, Germany Less <<
NCT01233232 Scientific Terminology Chronic... More >> Obstructive Pulmonary Disease (COPD) Laymen Terminology Chronic Bronchitis and Emphysema Less << Phase 2 Completed - Bulgaria ... More >> Research Site Sofia, Bulgaria Germany Research Site Berlin, Germany Research Site GROßHANSDORF, Germany Hungary Research Site Debrecen, Hungary Research Site Pécs, Hungary Research Site Szeged, Hungary Research Site Százhalombatta, Hungary Ukraine Research Site Kyiv, Ukraine Less <<
NCT01890148 - Completed - -
NCT00953888 Healthy Phase 1 Completed - United Kingdom ... More >> Research Site Nottingham, United Kingdom Less <<
NCT01480739 Chemokine Receptor 2 (CXCR2) A... More >>ntagonist Less << Phase 1 Completed - United Kingdom ... More >> London, UK, United Kingdom Less <<
NCT01051505 Healthy Phase 1 Completed - United Kingdom ... More >> Research Site London Bridge, United Kingdom Less <<
NCT01100047 Healthy Phase 1 Completed - United Kingdom ... More >> Research Site Croydon, United Kingdom Less <<
NCT01704495 - Completed - -
NCT01704495 Asthma Phase 2 Completed - -
NCT01332903 Healthy Phase 1 Completed - United Kingdom ... More >> Research Site London, United Kingdom Less <<
NCT03177187 Metastatic Castration Resistan... More >>t Prostate Cancer Less << Phase 1 Phase 2 Not yet recruiting December 2020 -
NCT01735240 Asthma, Pharm... More >>acokinetics, Cmax, Tmax, λz, AUC, Ketoconazole, Metabolite Less << Phase 1 Completed - United Kingdom ... More >> London, United Kingdom Less <<
NCT01083238 Chronic Obstructive Pulmonary ... More >>Disease Less << Phase 1 Completed - United Kingdom ... More >> Research Site London, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.10mL

0.42mL

0.21mL

10.49mL

2.10mL

1.05mL

20.99mL

4.20mL

2.10mL

References

 

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