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Chemical Structure| 524-17-4 Chemical Structure| 524-17-4

Structure of Dauricine
CAS No.: 524-17-4

Chemical Structure| 524-17-4

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Dauricine is a bisbenzylisoquinoline alkaloid with anti-inflammatory activity. It inhibits the proliferation and invasion of colon cancer cells by suppressing NF-κB activation and induces apoptosis in a dose-dependent manner.

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Product Details of Dauricine

CAS No. :524-17-4
Formula : C38H44N2O6
M.W : 624.77
SMILES Code : OC1=CC=C(C[C@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC=C(C[C@H]5N(C)CCC6=C5C=C(OC)C(OC)=C6)C=C4
MDL No. :MFCD26960929

Safety of Dauricine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of Dauricine

pyroptosis

Isoform Comparison

Biological Activity

Description
Dauricine, a bisbenzylisoquinoline alkaloid derived from Menispermum dauricum, exhibits anti-inflammatory properties. It hampers cell proliferation and invasion and prompts apoptosis by inhibiting NF-κB activation in a dose- and time-dependent manner in colon cancer[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.60mL

0.32mL

0.16mL

8.00mL

1.60mL

0.80mL

16.01mL

3.20mL

1.60mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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