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Chemical Structure| 23555-00-2 Chemical Structure| 23555-00-2

Structure of Hoechst 34580
CAS No.: 23555-00-2

Chemical Structure| 23555-00-2

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Hoechst 34580 is a cell-permeable fluorescent dye for staining DNA and nuclei.

Synonyms: HOE 34580

4.5 *For Research Use Only !

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Product Details of Hoechst 34580

CAS No. :23555-00-2
Formula : C27H29N7
M.W : 451.57
SMILES Code : CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(N(C)C)C=C6)N5)=C4)N3)=C2)CC1
Synonyms :
HOE 34580
MDL No. :MFCD25541584
InChI Key :VMCOQLKKSNQANE-UHFFFAOYSA-N
Pubchem ID :448202

Safety of Hoechst 34580

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Isoform Comparison

Biological Activity

Description
Hoechst 34580 is a nuclear marker dye in Hoechst series, primarily binding to the A/T-rich regions of DNA strands. Its binding affinity is not restricted to DNA, but the fluorescence intensity is significantly enhanced when bound to A/T-rich double-stranded DNA, making it a valuable tool for live cell labeling. The fluorescence intensity of Hoechst dye increases with the solution's pH, enabling its application across a range of biological research fields[1].

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