Structure of Zanubrutinib
CAS No.: 1691249-45-2
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor.
Synonyms: BGB-3111
4.5
*For Research Use Only !
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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| CAS No. : | 1691249-45-2 |
| Formula : | C27H29N5O3 |
| M.W : | 471.55 |
| SMILES Code : | O=C(C1=C2NCC[C@@H](C3CCN(C(C=C)=O)CC3)N2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4)N |
| Synonyms : |
BGB-3111
|
| MDL No. : | MFCD31567461 |
| InChI Key : | RNOAOAWBMHREKO-QFIPXVFZSA-N |
| Pubchem ID : | 135565884 |
| GHS Pictogram: |
|
| Signal Word: | Warning |
| Hazard Statements: | H302-H315-H319-H335 |
| Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
| NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
| NCT04172246 | Mature B-cell Malignancies | PHASE1|PHASE2 | ACTIVE_NOT_RECRUITING | 2025-06-30 | Nagoya University Hospital, Na... More >>goya, Aichi, 466-8560, Japan|Toyohashi Municipal Hospital, Toyohashi, Aichi, 441-8570, Japan|Chiba Cancer Center, Chibashi, Chiba, 260-8717, Japan|Matsuyama Red Cross Hospital, Matsuyamashi, Ehime, 790 8524, Japan|Kurume University Hospital, Kurume, Fukuoka, 830-0011, Japan|National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido, 003-0804, Japan|Aiiku Hospital, Sapporo, Hokkaido, 064-0804, Japan|Kobe City Medical Center General Hospital, Kobe, Hyogo, 650-0047, Japan|Kanagawa Cancer Center, Yokohamashi, Kanagawa, 241-8515, Japan|National Cancer Center Hospital, Chuoku, Tokyo, 104-0045, Japan|Aomori Prefectural Central Hospital, Aomori, 030-8553, Japan|Gifu Municipal Hospital, Gifu, 500-8513, Japan|The Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, 852-8511, Japan|National Hospital Organization Okayama Medical Center, Okayama, 701-1192, Japan|Yokohama Municipal Citizens Hospital, Yokohamashi, 221-0855, Japan Less << |
| NCT06341556 | Mantle Cell Lymphoma|Maintenan... More >>ce Therapy Less << | PHASE2 | RECRUITING | 2025-06-28 | Fudan University Shanghai Canc... More >>er Center, Shanghai, Shanghai, 200032, China|Shanghai Cancer Center, Shanghai, Shanghai, 200032, China Less << |
| NCT05767398 | Healthy Volunteers | PHASE1 | COMPLETED | 2023-04-28 | Fortrea Clinical Research Unit... More >>, Dallas, Texas, 75247, United States Less << |
| NCT05214391 | Immune Thrombocytopenia|Treatm... More >>ent Less << | PHASE2 | UNKNOWN | 2024-06-30 | Chinese Academy of Medical Sci... More >>ence and Blood Disease Hospital, Tianjin, Tianjin, 300020, China Less << |
| NCT03465059 | Hepatic Insufficiency & Health... More >>y Subjects Less << | PHASE1 | COMPLETED | 2018-10-19 | University of Miami, Miami, Fl... More >>orida, 33124, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States Less << |
| NCT04116437 | Chronic Lymphocytic Leukemia/S... More >>mall Lymphocytic Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia Less << | PHASE2 | ACTIVE_NOT_RECRUITING | 2025-10-25 | Arizona Oncology Associates, P... More >>c Hope, Tucson, Arizona, 85711, United States|Rocky Mountain Cancer Centers (Williams) Usor, Aurora, Colorado, 80012, United States|Christiana Care, Newark, Delaware, 19713, United States|Scri Florida Cancer Specialists South, Fort Myers, Florida, 33901, United States|St Century Oncology, Jacksonville, Florida, 32204, United States|Mid Florida Hematology and Oncology Center, Orange City, Florida, 32763, United States|Scri Florida Cancer Specialists North, Saint Petersburg, Florida, 33705, United States|Healthcare Research Network Iii, Llc, Tinley Park, Illinois, 60487, United States|Minnesota Oncology Burnsville Clinic, Burnsville, Minnesota, 55337, United States|Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, 89169, United States|Summit Medical Group, Florham Park, New Jersey, 07932, United States|Morristown Medical Center, Morristown, New Jersey, 07960, United States|Clinical Research Alliance, Inc, Westbury, New York, 11590, United States|Oncology Associates of Oregon Willamette Valley Cancer Center, Eugene, Oregon, 97401, United States|St Lukes University Health Network, Bethlehem, Pennsylvania, 18015, United States|Abington Hematology Oncology Associates, Horsham, Pennsylvania, 19044, United States|Tennessee Oncology, Pllc Nashville, Nashville, Tennessee, 37203, United States|Texas Oncology Amarillo, Amarillo, Texas, 79106, United States|Baylor Research Institute, Dallas, Texas, 75246, United States|Texas Oncology McAllen South Second Street, McAllen, Texas, 78503, United States|Texas Oncology Tyler Longview, Tyler, Texas, 75702, United States|Us Oncology Virginia Cancer Specialists, Pc, Fairfax, Virginia, 22031, United States|Virginia Oncology Associates Hampton, Virginia Beach, Virginia, 23456, United States|Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109, United States|Medical Oncology Associates, Spokane, Washington, 99208, United States|Ssm Health Cancer Care Dean Medical Center, Madison, Wisconsin, 53717, United States Less << |
| NCT05596097 | Diffuse Large B-cell Lymphoma ... More >>(DLBCL) Less << | PHASE2 | NOT_YET_RECRUITING | 2026-07-30 | The First Hospital of Lanzhou ... More >>University, Lanzhou, Gansu, 730000, China Less << |
| NCT05640102 | Waldenstrom Macroglobulinemia | RECRUITING | 2025-12-27 | Clearview Cancer Institute, Hu... More >>ntsville, Alabama, 35805, United States|Mitchell Cancer Institute, Mobile, Alabama, 36604, United States|City of Hope National Medical Center, Duarte, California, 91010, United States|Los Angeles Cancer Network (Lacn), Glendale, California, 91204, United States|Valkyrie Clinical Trials, Los Angeles, California, 90067, United States|Eisenhower Medical Center, Lucy Curci Cancer Center, Rancho Mirage, California, 92270, United States|Pacific Central Coast Health Centers, Slo Oncology and Hematology Health Center, San Luis Obispo, California, 93401, United States|Pacific Central Coast Health Centers, Mission Hope Medical Oncology, Santa Maria, California, 93454, United States|Brcr Medical Center, Inc, Plantation, Florida, 33322, United States|Tulane Cancer Center, New Orleans, Louisiana, 70112, United States|Hattiesburg Hematology and Oncology Clinic, Hattiesburg, Mississippi, 39401, United States|Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, 89169, United States|Summit Medical Group, Florham Park, New Jersey, 07932, United States|Morristown Medical Center, Morristown, New Jersey, 07960, United States|Clinical Research Alliance, Inc, Westbury, New York, 11590, United States|Pan American Oncology Trials, Llc, Rio Piedras, 00935, Puerto Rico|Auxilio Mutuo Cancer Center, San Juan, 00917, Puerto Rico Less << | |
| NCT06021977 | Refractory/Relapsed Autoimmune... More >> Hemolytic Anemia Less << | PHASE2 | RECRUITING | 2025-12-31 | Regenerative Medicine Center, ... More >>Tianjin, Tianjin, 300131, China Less << |
| NCT04743687 | Idiopathic Multicentric Castle... More >>man's Disease Less << | PHASE2 | UNKNOWN | 2025-01-01 | Peking Union Medical College H... More >>ospital, Beijing, Beijing, 100005, China Less << |
| NCT04163523 | Healthy Volunteers | PHASE1 | COMPLETED | 2016-07-21 | Cancer Care Wollongong, Wollon... More >>gong, New South Wales, 2500, Australia|Austin Health, Heidelberg, Victoria, 3084, Australia|Peter Maccallum Cancer Centre, Melbourne, Victoria, 3000, Australia|Nucleus Network, Melbourne, Victoria, 3004, Australia|Linear Clinical Research, Nedlands, Western Australia, 6009, Australia Less << |
| NCT03332173 | Waldenstr?m's Macroglobulinemi... More >>a (WM) Less << | PHASE2 | COMPLETED | 2021-01-11 | Cancer Hospital Chinese Academ... More >>y of Medical Sciences, Beijing, Beijing, 100021, China|Peking Union Medical College Hospital, Beijing, Beijing, 100730, China|Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong, 510080, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China|Jiangsu Province Hospital, Nanjing, Jiangsu, 210029, China|The First Affiliated Hospital of Soochow University Branch Shizi, Suzhou, Jiangsu, 215006, China|Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, 200025, China|West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China|The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China Less << |
| NCT05068440 | Relapsed Diffuse Large B-cell ... More >>Lymphoma|Refractory Diffuse Large B-cell Lymphoma Less << | PHASE2 | RECRUITING | 2024-12-30 | Anhui Provincial Cancer Hospit... More >>al Aka West Branch of Anhui Province Hospital, Hefei, Anhui, 230088, China|Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing, 100050, China|Fujian Cancer Hospital, Fuzhou, Fujian, 350014, China|Sun Yat Sen University Cancer Center, Guangzhou, Guangdong, 510060, China|Guangdong Provincial Peoples Hospital Huifu Branch, Guangzhou, Guangdong, 510120, China|The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China|The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, 515041, China|Hainan Cancer Hospital, Haikou, Hainan, 570312, China|Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150000, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China|Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China|The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China|Hunan Cancer Hospital, Changsha, Hunan, 410013, China|The First Affiliated Hospital of Nanchang University Branch Donghu, Nanchang, Jiangxi, 330006, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|Liaoning Cancer Hospital and Institute, Shenyang, Liaoning, 110042, China|Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, 200025, China|Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, 030013, China|West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China|Yunnan Cancer Hospital, Kunming, Yunnan, 650100, China|The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China|Zhejiang University College of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, 310009, China|Taizhou Hospital of Zhejiang, Taizhou, Zhejiang, 317000, China Less << |
| NCT06441214 | Waldenstr?m's Macroglobulinemi... More >>a (WM) Less << | NOT_YET_RECRUITING | 2025-07-26 | A.O. SS. Antonio e Biagio e Ce... More >>sare Arrigo - S.C.D.U. Ematologia, Alessandria, Italy|A.O.U. Ospedali Riuniti - Clinica di Ematologia, Ancona, Italy|Ospedale C. e G. Mazzoni - U.O.C. di Ematologia, Ascoli Piceno, Italy|AOU Policlinico Consorziale - U.O. Ematologia con Trapianto, Bari, Italy|Nuovo Ospedale degli Infermi - SSD Ematologia, Biella, Italy|Policlinico S. Orsola-Malpighi - Istituto di Ematologia "Seragnoli", Bologna, Italy|Ospedale Centrale di Bolzano - Divisione di Ematologia e T.M.O., Bolzano, Italy|Azienda Ospedaliera Universitaria Policlinico - S. Marco - UOC di Ematologia, Catania, Italy|Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna - Ematologia e fisiopatologia della coagulazione, Ferrara, Italy|Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia, Firenze, Italy|Ospedale Policlinico San Martino S.S.R.L. - IRCCS per l'Oncologia - Ematologia e terapie cellulari, Genova, Italy|ASST Grande Ospedale Metropolitano Niguarda - S.C. Ematologia, Milano, Italy|IEO Istituto Europeo di Oncologia - Divisione Ematoncologia, Milano, Italy|Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda - Ematologia, Milano, Italy|AOU Maggiore della Carità di Novara - SCDU Ematologia, Novara, Italy|AOU di Padova - Ematologia, Padova, Italy|A.O. Ospedali Riuniti Villa Sofia-Cervello - Divisione di Ematologia, Palermo, Italy|RCCS Policlinico S. Matteo di Pavia - Div. di Ematologia, Pavia, Italy|P.O. Spirito Santo di Pescara - UOC Ematologia Dipartimento Oncologico Ematologico - ASL Pescara, Pescara, Italy|AOU Pisana - U.O. Ematologia, Pisa, Italy|Ospedale delle Croci - Ematologia, Ravenna, Italy|Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia, Reggio Emilia, Italy|Università Cattolica Sacro Cuore - Ematologia, Roma, Italy|AOU Senese - U.O.C. Ematologia, Siena, Italy|Ospedale "G. Mazzini" - UOS Ematologia, Teramo, Italy|A.O.U. Città della Salute e della Scienza di Torino - Ematologia Universitaria, Torino, Italy|A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia, Torino, Italy|Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) - SOC Clinica Ematologica, Udine, Italy Less << | |
| NCT03206970 | Refractory Mantle Cell Lymphom... More >>a|Relapsed Mantle Cell Lymphoma Less << | PHASE2 | COMPLETED | 2020-09-08 | Beijing Cancer Hospital, Beiji... More >>ng, Beijing, 100142, China|Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China|Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China|Jiangsu Province Hospital, Nanjing, Jiangsu, 210029, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|Fudan University Shanghai Cancer Center, Shanghai, Shanghai, 200000, China|West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China|Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, 300060, China|The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China|Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310022, China Less << |
| NCT05922839 | Warm Autoimmune Hemolytic Anem... More >>ia Less << | PHASE2 | RECRUITING | 2025-12-25 | Peking Union Medical College H... More >>ospital, Beijing, Beijing, 100730, China Less << |
| NCT05117814 | CNS Lymphoma | RECRUITING | 2025-07-25 | Peking University People's Hos... More >>pital, Beijing, Beijing, 100044, China Less << | |
| NCT02343120 | B-cell Malignancies | PHASE1|PHASE2 | COMPLETED | 2021-03-31 | Banner MD Anderson Cancer Cent... More >>re, Gilbert, Arizona, 85234, United States|University of Michigan, Ann Arbor, Michigan, 48109, United States|Mayo Clinic, Rochester, Minnesota, 55901, United States|M.D. Anderson Cancer Center, Houston, Texas, 77030, United States|Concord Repatriation General Hospital, Concord, New South Wales, Australia|St George Hospital, Sydney, New South Wales, Australia|Westmead Hospital, Westmead, New South Wales, Australia|Princess Alexandra Hospital, Brisbane, Queensland, Australia|Royal Hobart Hospital, Hobart, Tasmania, Australia|Monash Health, Clayton, Victoria, Australia|Austin Health, Heidelberg, Victoria, Australia|St Vincent's Hospital, Melbourne, Victoria, Australia|Peter MacCallum Cancer Centre, East Melbourne, Parkville, Victoria, 3050, Australia|Melbourne Health, Parkville, Victoria, Australia|Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia|Policlinico S.Orsola Malpighi, AOU di Bologna, Bologna, Italy|Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda, Milano, Italy|Dong-A University Medical Centre, Busan, Korea, Republic of|Inje University Busan Paik Hospital, Busan, Korea, Republic of|National Cancer Center, Goyang-si, Korea, Republic of|Samsung Medical Center, Seoul, Korea, Republic of|North Shore Hospital, Auckland, New Zealand|Derriford Hospital, Plymouth, Devon, United Kingdom Less << |
| NCT03145064 | Diffuse Large B-cell Lymphoma | PHASE2 | COMPLETED | 2020-09-03 | Beijing Cancer Hospital, Beiji... More >>ng, Beijing, 100142, China|Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150000, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|The First Affiliated Hospital of Soochow University Branch Shizi, Suzhou, Jiangsu, 215006, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|Fudan University Shanghai Cancer Center, Shanghai, Shanghai, 200000, China|Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, 200025, China|West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China|Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, 300060, China|Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310022, China Less << |
| NCT06489184 | CLL | NOT_YET_RECRUITING | 2025-12-30 | Peking University People's Hos... More >>pital, Beijing, Beijing, 100044, China Less << | |
| NCT05547399 | Healthy Volunteers | PHASE1 | COMPLETED | 2022-12-07 | Fortrea Clinical Research Unit... More >>, Dallas, Texas, 75247, United States Less << |
| NCT05279872 | Immune Thrombocytopenia|Bruton... More >> Tyrosine Kinase Less << | PHASE2 | COMPLETED | 2022-10-30 | Peking University Insititute o... More >>f Hematology, Peking University People's Hospital, Beijing, Beijing, 100010, China Less << |
| NCT03206918 | Relapsed or Refractory Chronic... More >> Lymphocytic Leukemia|Relapsed or Refractory Small Lymphocytic Lymphoma Less << | PHASE2 | COMPLETED | 2020-09-10 | Peking University Peoples Hosp... More >>ital, Beijing, Beijing, 100044, China|Peking Union Medical College Hospital, Beijing, Beijing, 100730, China|Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China|Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China|Jiangsu Province Hospital, Nanjing, Jiangsu, 210029, China|The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China Less << |
| NCT03189524 | B-cell Lymphoma | PHASE1 | COMPLETED | 2020-08-26 | Beijing Cancer Hospital, Beiji... More >>ng, Beijing, 100142, China|Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China|Jiangsu Province Hospital, Nanjing, Jiangsu, 210029, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China Less << |
| NCT04052854 | Waldenstr?m Macroglobulinemia | NO_LONGER_AVAILABLE | - | Eisenhower Desert Cardiology C... More >>enter, Rancho Mirage, California, 92270, United States|Sansum Clinic and Ridley Tree Cancer Center, Santa Barbara, California, 93105, United States|Maryland Oncology Hematology, Pa, Columbia, Maryland, 21044, United States|Dana Farber Cancer Institute, Boston, Massachusetts, 02215, United States|Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, 89169, United States|Morristown Medical Center, Morristown, New Jersey, 07960, United States|Icahn School of Medicine At Mount Sinai, New York, New York, 10029, United States|Clinical Research Alliance, Inc, Westbury, New York, 11590, United States|Texas Oncology Austin Midtown, Round Rock, Texas, 78681, United States|Texas Oncology Tyler Longview, Tyler, Texas, 75702, United States Less << | |
| NCT05320575 | HLH | PHASE3 | COMPLETED | 2023-08-01 | Beijing Friendship Hospital, C... More >>apital Medical University, Beijing, China Less << |
| NCT03846427 | Marginal Zone Lymphoma|MZL | PHASE2 | COMPLETED | 2022-05-04 | Clinical Research Alliance, In... More >>c, Westbury, New York, 11590, United States|The Charlotte Mecklenburg Hospital Authority, Charlotte, North Carolina, 28203, United States|Canberra Hospital, Garran, Australian Capital Territory, 2605, Australia|Concord Repatriation General Hospital, Concord, New South Wales, 2139, Australia|The Saint George Hospital Kogarah, Kogarah, New South Wales, 2217, Australia|Princess Alexandra Hospital, Brisbane, Queensland, 4102, Australia|Flinders Medical Centre, Bedford PK, South Australia, 5042, Australia|Box Hill Hospital, Box Hill, Victoria, 3128, Australia|Monash Health, Clayton, Victoria, 3168, Australia|Peninsula Private Hospital, Frankston, Victoria, 3199, Australia|Peking University Third Hospital, Beijing, Beijing, 100000, China|Henan Cancer Hospital, Zhengzhou, Henan, 450000, China|Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, 300020, China|The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China|University Hospital Vinohrady Hematology Department, Prague, 10034, Czechia|Centre de Lutte Contre Le Cancer Institut Bergonie, Bordeaux, 33076, France|Hopital de La Conception Aphm, Marseille Cedex, 13005, France|Hopital Saint Louis, Paris, 75010, France|Chu Hopital Lyon Sud, PierreBenite, 69495, France|Policlinico Sorsola Malpighi, Aou Di Bologna, Bologna, 40138, Italy|Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, 20162, Italy|Universita Degli Studi Di Modena Azienda Ospedaliere Policlinco, Modena, 41124, Italy|Azienda Ospedaliera S Maria Di Terni, Terni, 05100, Italy|Ao Citta Della Salute E Della Scienza Di Torino Presidio O, Torino, 10126, Italy|Severance Hospital Yonsei University Health System, Seoul, Seoul Teugbyeolsi, 03722, Korea, Republic of|Auckland City Hospital, Auckland, 1023, New Zealand|North Shore Hospital, Takapuna, 0622, New Zealand|Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, United Kingdom|The Christie Hospital, Greater Manchester, M20 4BX, United Kingdom|University College Hospital, London, NW1 2PG, United Kingdom|Royal Marsden Hospital, London, SW3 6JJ, United Kingdom Less << |
Tags: Zanubrutinib | BGB-3111 | Amides | BTK | Organic Building Blocks | Protein Tyrosine Kinase/RTK | Angiogenesis | 1691249-45-2
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| Code | Phrase |
| P101 | If medical advice is needed,have product container or label at hand. |
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| P103 | Read label before use |
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| P202 | Do not handle until all safety precautions have been read and understood. |
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| P211 | Do not spray on an open flame or other ignition source. |
| P220 | Keep/Store away from clothing/combustible materials. |
| P221 | Take any precaution to avoid mixing with combustibles |
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| P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
| P230 | Keep wetted |
| P231 | Handle under inert gas. |
| P232 | Protect from moisture. |
| P233 | Keep container tightly closed. |
| P234 | Keep only in original container. |
| P235 | Keep cool |
| P240 | Ground/bond container and receiving equipment. |
| P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
| P242 | Use only non-sparking tools. |
| P243 | Take precautionary measures against static discharge. |
| P244 | Keep reduction valves free from grease and oil. |
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| P262 | Do not get in eyes, on skin, or on clothing. |
| P263 | Avoid contact during pregnancy/while nursing. |
| P264 | Wash hands thoroughly after handling. |
| P265 | Wash skin thouroughly after handling. |
| P270 | Do not eat, drink or smoke when using this product. |
| P271 | Use only outdoors or in a well-ventilated area. |
| P272 | Contaminated work clothing should not be allowed out of the workplace. |
| P273 | Avoid release to the environment. |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
| P281 | Use personal protective equipment as required. |
| P282 | Wear cold insulating gloves/face shield/eye protection. |
| P283 | Wear fire/flame resistant/retardant clothing. |
| P284 | Wear respiratory protection. |
| P285 | In case of inadequate ventilation wear respiratory protection. |
| P231 + P232 | Handle under inert gas. Protect from moisture. |
| P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
| Code | Phrase |
| P301 | IF SWALLOWED: |
| P304 | IF INHALED: |
| P305 | IF IN EYES: |
| P306 | IF ON CLOTHING: |
| P307 | IF exposed: |
| P308 | IF exposed or concerned: |
| P309 | IF exposed or if you feel unwell: |
| P310 | Immediately call a POISON CENTER or doctor/physician. |
| P311 | Call a POISON CENTER or doctor/physician. |
| P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
| P313 | Get medical advice/attention. |
| P314 | Get medical advice/attention if you feel unwell. |
| P315 | Get immediate medical advice/attention. |
| P320 | |
| P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
| P321 | |
| P322 | |
| P330 | Rinse mouth. |
| P331 | Do NOT induce vomiting. |
| P332 | IF SKIN irritation occurs: |
| P333 | If skin irritation or rash occurs: |
| P334 | Immerse in cool water/wrap n wet bandages. |
| P335 | Brush off loose particles from skin. |
| P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
| P337 | If eye irritation persists: |
| P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
| P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
| P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
| P342 | If experiencing respiratory symptoms: |
| P350 | Gently wash with plenty of soap and water. |
| P351 | Rinse cautiously with water for several minutes. |
| P352 | Wash with plenty of soap and water. |
| P353 | Rinse skin with water/shower. |
| P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
| P361 | Remove/Take off immediately all contaminated clothing. |
| P362 | Take off contaminated clothing and wash before reuse. |
| P363 | Wash contaminated clothing before reuse. |
| P370 | In case of fire: |
| P371 | In case of major fire and large quantities: |
| P372 | Explosion risk in case of fire. |
| P373 | DO NOT fight fire when fire reaches explosives. |
| P374 | Fight fire with normal precautions from a reasonable distance. |
| P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
| P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
| P378 | |
| P380 | Evacuate area. |
| P381 | Eliminate all ignition sources if safe to do so. |
| P390 | Absorb spillage to prevent material damage. |
| P391 | Collect spillage. Hazardous to the aquatic environment |
| P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
| P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
| P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
| P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
| P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
| P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
| P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
| P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
| P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
| P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
| P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
| P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
| P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
| P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
| P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
| P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
| P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
| P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
| P370 + P376 | In case of fire: Stop leak if safe to Do so. |
| P370 + P378 | In case of fire: |
| P370 + P380 | In case of fire: Evacuate area. |
| P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
| P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
| Code | Phrase |
| P401 | |
| P402 | Store in a dry place. |
| P403 | Store in a well-ventilated place. |
| P404 | Store in a closed container. |
| P405 | Store locked up. |
| P406 | Store in corrosive resistant/ container with a resistant inner liner. |
| P407 | Maintain air gap between stacks/pallets. |
| P410 | Protect from sunlight. |
| P411 | |
| P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
| P413 | |
| P420 | Store away from other materials. |
| P422 | |
| P402 + P404 | Store in a dry place. Store in a closed container. |
| P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P403 + P235 | Store in a well-ventilated place. Keep cool. |
| P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
| P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
| P411 + P235 | Keep cool. |
Disposal | |
| Code | Phrase |
| P501 | Dispose of contents/container to ... |
| P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
| Code | Phrase |
| H200 | Unstable explosive |
| H201 | Explosive; mass explosion hazard |
| H202 | Explosive; severe projection hazard |
| H203 | Explosive; fire, blast or projection hazard |
| H204 | Fire or projection hazard |
| H205 | May mass explode in fire |
| H220 | Extremely flammable gas |
| H221 | Flammable gas |
| H222 | Extremely flammable aerosol |
| H223 | Flammable aerosol |
| H224 | Extremely flammable liquid and vapour |
| H225 | Highly flammable liquid and vapour |
| H226 | Flammable liquid and vapour |
| H227 | Combustible liquid |
| H228 | Flammable solid |
| H229 | Pressurized container: may burst if heated |
| H230 | May react explosively even in the absence of air |
| H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
| H240 | Heating may cause an explosion |
| H241 | Heating may cause a fire or explosion |
| H242 | Heating may cause a fire |
| H250 | Catches fire spontaneously if exposed to air |
| H251 | Self-heating; may catch fire |
| H252 | Self-heating in large quantities; may catch fire |
| H260 | In contact with water releases flammable gases which may ignite spontaneously |
| H261 | In contact with water releases flammable gas |
| H270 | May cause or intensify fire; oxidizer |
| H271 | May cause fire or explosion; strong oxidizer |
| H272 | May intensify fire; oxidizer |
| H280 | Contains gas under pressure; may explode if heated |
| H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
| H290 | May be corrosive to metals |
Health hazards | |
| Code | Phrase |
| H300 | Fatal if swallowed |
| H301 | Toxic if swallowed |
| H302 | Harmful if swallowed |
| H303 | May be harmful if swallowed |
| H304 | May be fatal if swallowed and enters airways |
| H305 | May be harmful if swallowed and enters airways |
| H310 | Fatal in contact with skin |
| H311 | Toxic in contact with skin |
| H312 | Harmful in contact with skin |
| H313 | May be harmful in contact with skin |
| H314 | Causes severe skin burns and eye damage |
| H315 | Causes skin irritation |
| H316 | Causes mild skin irritation |
| H317 | May cause an allergic skin reaction |
| H318 | Causes serious eye damage |
| H319 | Causes serious eye irritation |
| H320 | Causes eye irritation |
| H330 | Fatal if inhaled |
| H331 | Toxic if inhaled |
| H332 | Harmful if inhaled |
| H333 | May be harmful if inhaled |
| H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
| H335 | May cause respiratory irritation |
| H336 | May cause drowsiness or dizziness |
| H340 | May cause genetic defects |
| H341 | Suspected of causing genetic defects |
| H350 | May cause cancer |
| H351 | Suspected of causing cancer |
| H360 | May damage fertility or the unborn child |
| H361 | Suspected of damaging fertility or the unborn child |
| H361d | Suspected of damaging the unborn child |
| H362 | May cause harm to breast-fed children |
| H370 | Causes damage to organs |
| H371 | May cause damage to organs |
| H372 | Causes damage to organs through prolonged or repeated exposure |
| H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
| Code | Phrase |
| H400 | Very toxic to aquatic life |
| H401 | Toxic to aquatic life |
| H402 | Harmful to aquatic life |
| H410 | Very toxic to aquatic life with long-lasting effects |
| H411 | Toxic to aquatic life with long-lasting effects |
| H412 | Harmful to aquatic life with long-lasting effects |
| H413 | May cause long-lasting harmful effects to aquatic life |
| H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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