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Chemical Structure| 65815-76-1 Chemical Structure| 65815-76-1

Structure of AA38-3
CAS No.: 65815-76-1

Chemical Structure| 65815-76-1

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AA38-3 is a serine hydrolase (SH) inhibitor that effectively inhibits three SHs: ABHD6, ABHD11, and FAAH, providing potential applications in lipid metabolism and neuroprotection research.

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Product Details of AA38-3

CAS No. :65815-76-1
Formula : C12H14N2O4
M.W : 250.25
SMILES Code : O=C(N1CCCCC1)OC2=CC=C([N+]([O-])=O)C=C2
MDL No. :MFCD00276294
InChI Key :DHSYPQIMNAYLCG-UHFFFAOYSA-N
Pubchem ID :726751

Safety of AA38-3

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
AA38-3 is another serine hydrolase inhibitor, albeit with a more restricted scope of activity compared to AA26-9. It can inhibit three specific serine hydrolases: ABHD6, ABHD11, and FAAH. This selectivity may offer insights into designing targeted therapies or research tools for studying the physiological and pathological roles of these enzymes[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.00mL

0.80mL

0.40mL

19.98mL

4.00mL

2.00mL

39.96mL

7.99mL

4.00mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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