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Chemical Structure| 1042735-18-1 Chemical Structure| 1042735-18-1

Structure of ABC1183
CAS No.: 1042735-18-1

Chemical Structure| 1042735-18-1

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ABC1183 is an orally active dual GSK3 and CDK9 inhibitor, with IC50 values of 657 nM, 327 nM, and 321 nM for GSK3β, GSK3α, and CDK9/cyclin T1, respectively. This compound exhibits anti-inflammatory and anticancer activity, suitable for research on cancer and inflammation-related diseases.

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Product Details of ABC1183

CAS No. :1042735-18-1
Formula : C18H14N4OS
M.W : 334.40
SMILES Code : N#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1
MDL No. :MFCD32204423

Safety of ABC1183

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of ABC1183

PI3K-AKT
Hedgehog

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.99mL

0.60mL

0.30mL

14.95mL

2.99mL

1.50mL

29.90mL

5.98mL

2.99mL

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