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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 133550-35-3 Chemical Structure| 133550-35-3

Structure of AG 494
CAS No.: 133550-35-3

Chemical Structure| 133550-35-3

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AG-494 is an inhibitor of EGFR with an IC50 value of 0.7 µM and it is inactive toward ErbB2, PDGFR and insulin receptor kinase.

Synonyms: Tyrphostin AG 494

4.5 *For Research Use Only !

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Product Details of AG 494

CAS No. :133550-35-3
Formula : C16H12N2O3
M.W : 280.28
SMILES Code : O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Synonyms :
Tyrphostin AG 494
MDL No. :MFCD00209863
InChI Key :HKHOVJYOELRGMV-XYOKQWHBSA-N
Pubchem ID :5328771

Safety of AG 494

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315-H319
Precautionary Statements:P301+P310-P305+P351+P338
Class:6.1
UN#:2811
Packing Group:

Related Pathways of AG 494

RTK
JAK-STAT

Isoform Comparison

Biological Activity

Target
  • EGFR/ErbB1

    EGFR, IC50:1.2 μM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.57mL

0.71mL

0.36mL

17.84mL

3.57mL

1.78mL

35.68mL

7.14mL

3.57mL

References

 

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