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Chemical Structure| 378775-98-5 Chemical Structure| 378775-98-5

Structure of AK-IN-1
CAS No.: 378775-98-5

Chemical Structure| 378775-98-5

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AK-IN-1 is a selective adenosine kinase (AK) inhibitor that exhibits competitive inhibition against adenosine but non-competitive inhibition against ATP. At concentrations of 2, 4, and 10 µM, this compound inhibits AK activity by 86%, 87%, and 89%, respectively, indicating broad applications in ischemia, inflammation, and epilepsy research.

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Product Details of AK-IN-1

CAS No. :378775-98-5
Formula : C22H21N3O4
M.W : 391.42
SMILES Code : COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)C4=C(NCCO)N=CN=C4O2)C=C1
InChI Key :ARBUGBBNEFAECO-UHFFFAOYSA-N
Pubchem ID :2059510

Safety of AK-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
AK-IN-1 is an inhibitor of adenosine kinase (AK) that competitively inhibits adenosine (Ado) but not ATP. AK-IN-1 inhibits 86%, 87%, and 89% of AK activity at concentrations of 2, 4, and 10 µM, respectively. It holds promise for research across various disease areas, including ischemia, inflammation, and seizures [1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.55mL

0.51mL

0.26mL

12.77mL

2.55mL

1.28mL

25.55mL

5.11mL

2.55mL

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