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Type HazMat fee for 500 gram (Estimated)
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Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 41294-56-8 Chemical Structure| 41294-56-8

Structure of Alfacalcidol
CAS No.: 41294-56-8

Chemical Structure| 41294-56-8

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Alfacalcidol is a non-selective VDR activator medication.

Synonyms: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3; EB 644

4.5 *For Research Use Only !

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Product Details of Alfacalcidol

CAS No. :41294-56-8
Formula : C27H44O2
M.W : 400.64
SMILES Code : C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](CCCC(C)C)C)CCC/2)[H])O)O
Synonyms :
1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3; EB 644
MDL No. :MFCD00868328

Safety of Alfacalcidol

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H300
Precautionary Statements:P264-P301+P310
Class:6.1
UN#:2811
Packing Group:

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Huh7 cells 5.00 μM 6 days To evaluate the inhibitory effect of Alfacalcidol on SFTSV-induced cytopathic effect (CPE). The results showed that the EC50 value of Alfacalcidol was 1.59 ± 0.35 μM, indicating a dose-dependent protective effect against SFTSV infection. PMC11738768
Huh7 cells 1.59 ± 0.35 μM(EC50) 6 days To evaluate the inhibitory effect of Alfacalcidol on SFTSV-induced cytopathic effect (CPE). The results showed that Alfacalcidol significantly inhibited SFTSV-induced CPE in a dose-dependent manner. PMC11738768

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
ICR suckling mice Lethal SFTSV infection model Intraperitoneal injection 0.6 or 0.3 μg/kg Daily for 8 days To evaluate the therapeutic effect of Alfacalcidol on SFTSV-infected ICR suckling mice. The results showed that Alfacalcidol (0.6 μg/kg) provided 64% protection, significantly improving the survival rate of infected mice. PMC11738768
ICR suckling mice SFTSV lethal infection model Intraperitoneal injection 0.6 or 0.3 μg/kg Once daily for 8 days To evaluate the therapeutic effect of Alfacalcidol on SFTSV-infected ICR suckling mice. The results showed that Alfacalcidol (0.6 μg/kg/d) provided 64% protection, significantly improving the survival rate of infected mice. PMC11738768

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02069886 Thalassemia (Transfusion Delen... More >>dent) Less << Phase 4 Withdrawn December 2018 -
NCT03483441 Basal Cell Nevus Syndrome ... More >> Basal Cell Carcinoma Less << Phase 1 Recruiting May 1, 2023 United States, Arizona ... More >> University of Arizona College of Medicine Not yet recruiting Phoenix, Arizona, United States, 85004 Contact: Nathalie Zeitouni, MD    602-406-8222    Nathalie.Zeitouni@dignityhealth.org    Sub-Investigator: Nathalie Zeitouni, MD          United States, Ohio Cleveland Clinic Recruiting Cleveland, Ohio, United States, 44195 Contact: Jeff Negrey, MA    216-636-5504    negreyj2@ccf.org    Principal Investigator: Edward Maytin, MD          Sub-Investigator: Christine Warren, MD Less <<
NCT02542865 Growth and Development Not Applicable Completed - India ... More >> GSK Investigational Site Pune, India, 411001 Less <<
NCT03077048 Renal Insufficiency, Chronic Phase 1 Phase 2 Completed - Czechia ... More >> Thomayer Hospital Clinical - Pharmacology Unit (CPU) Prague, Czechia, 140 59 Less <<
NCT01321905 Cystic Fibrosis Phase 2 Unknown - Sweden ... More >> Stockholm Cystic Fibrosis Center, Karolinska University Hospital Huddinge Recruiting Stockholm, Sweden, 141 86 Contact: Lena Hjelte, Professor    0046858587359    Lena.Hjelte@karolinska.se Less <<
NCT01398202 Vitamin D Status as Reflected ... More >>by Serum 25-hydroxyvitamin D Less << Not Applicable Completed - Ireland ... More >> University College Cork Cork, Ireland Less <<
NCT01633658 Vitamin D Deficiency Not Applicable Withdrawn(Protocol has changed... More >>) Less << November 2013 United States, Nebraska ... More >> Creighton University Omaha, Nebraska, United States, 68131 Less <<
NCT02802449 Hypovitaminosis D Not Applicable Active, not recruiting July 2018 United States, California ... More >> Charles Drew University Los Angeles, California, United States, 90059 Less <<
NCT02063334 Vitamin D Receptor Target Gene... More >> Expression Serum 25(OH)D Concentration Less << Phase 1 Completed - Finland ... More >> University of Eastern Finland Kuopio, Finland, 70211 Less <<
NCT02091219 Vitamin D Deficiency Early Phase 1 Recruiting December 2019 United States, California ... More >> UCLA Clinical and Translational Research Center (CTRC) Not yet recruiting Los Angeles, California, United States, 90095 Contact: Albert Shieh, MD    424-248-5617    ashieh@mednet.ucla.edu    Contact: Gloria Kiel    (310) 825-1394    gskiel@mednet.ucla.edu    Principal Investigator: John S Adams, MD          Sub-Investigator: Albert Shieh, MD          University of California, Los Angeles Recruiting Los Angeles, California, United States, 90095 Less <<
NCT02525003 Serum 25-hydroxyvitamin D Conc... More >>entrations (25OHD) Less << Not Applicable Completed - Finland ... More >> Department of Food and Environmental Sciences, University of Helsinki Helsinki, Finland Less <<
NCT02293187 Vitamin D Deficiency ... More >> Sarcopenia Less << Not Applicable Active, not recruiting December 31, 2018 United States, Massachusetts ... More >> Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University Boston, Massachusetts, United States, 02111 Less <<
NCT02287779 Non-Alcoholic Steatohepatitis Phase 1 Completed - United States, Tennessee ... More >> New Orleans Center for Clinical Research Knoxsville, Tennessee, United States, 37920 Less <<
NCT02802449 - Active, not recruiting - -
NCT02527668 Osteopenia/Osteoporosis Phase 2 Active, not recruiting December 2018 Switzerland ... More >> Center on Aging and Mobility, Klinik für Geriatrie, UniversitätsSpital Zürich Zurich, Switzerland, 8091 Less <<
NCT02287779 - Completed - -
NCT03537027 Vitamin D Receptor Target Gene... More >> Expression Serum 25(OH)D Concentration Less << Phase 1 Completed - Finland ... More >> University of Eastern Finland Kuopio, Finland, 70211 Less <<
NCT03576716 Chronic Kidney Disease Phase 1 Enrolling by invitation December 2020 United States, Washington ... More >> University of Washington Seattle, Washington, United States, 98195 Less <<
NCT02678364 Vitamin D Deficiency Not Applicable Completed - Ireland ... More >> Human Dietary Studies Facility, School of Food and Nutritional Sciences, University College Cork Cork, Ireland Less <<
NCT03644212 Polycystic Ovary Syndrome ... More >> Vitamin D Deficiency Less << Phase 4 Completed - United States, New York ... More >> Maimonides Medical Center, OBGYN clinic Brooklyn, New York, United States, 11219 Less <<
NCT03401541 Vitamin D Deficiency ... More >> Fat Malabsorption Less << Early Phase 1 Recruiting May 2019 United States, Massachusetts ... More >> Solomon Carter Fuller Mental Health Center Recruiting Boston, Massachusetts, United States, 02118 Contact: Michael F Holick, MD, PhD    617-638-4546    mfholick@bu.edu Less <<
NCT01312714 End-Stage Renal Disease Phase 2 Completed - Denmark ... More >> Departments of Medical Research and Medicine, Holstebro Hospital Holstebro, Denmark, 7500 Less <<
NCT03155269 Growth and Development Not Applicable Completed - India ... More >> GSK Investigational Site Pune, India, 411001 Less <<
NCT01166165 Hypertension ... More >>Vitamin D Deficiency Less << Phase 2 Completed - Denmark ... More >> Department of Medical Research Holstebro, Denmark, 7500 Less <<
NCT01717989 - Completed - -
NCT01135576 Iron-deficiency Anemia Not Applicable Completed - -
NCT01717989 - Completed - -
NCT00882505 Vitamin D Deficiency Not Applicable Completed - United States, Illinois ... More >> Northwestern University Feinberg School of Medicine, Department of Dermatology Chicago, Illinois, United States, 60611 Less <<
NCT03310242 Vitamin D Deficiency ... More >> Cardiometabolic Risk Factors Less << Not Applicable Completed - -
NCT02136407 - Completed - Sweden ... More >> Sahlgrenska University Hospital Gothenburg, Sweden, 41345 Less <<
NCT02890823 Epilepsy Phase 4 Completed - -
NCT03391245 - Recruiting February 15, 2018 Egypt ... More >> Assiut University Recruiting Assiut, Egypt Contact: Hoda A Makhlouf, Professor    00201001529442    hamakhlouf@yahoo.com Less <<
NCT01548716 - Completed - United States, New York ... More >> Winthrop University Hospital Dialysis Unit Mineola, New York, United States, 11023 Winthrop University Hospital Mineola, New York, United States, 11501 Less <<
NCT03334136 Psoriasis Vit... More >>amin D Deficiency Less << Not Applicable Recruiting May 15, 2019 Norway ... More >> University Hospital of North Norway Recruiting Tromsø, Norway, 9038 Contact: Kjersti Danielsen, MD, PhD    +47 476 05 092    kjerstidanielsen2007@hotmail.com    Sub-Investigator: Marita Jenssen, MD          Principal Investigator: Kjersti Danielsen, MD, PhD Less <<
NCT01302704 - Withdrawn - United States, Nevada ... More >> Mike O'Callaghan Federal Hospital Nellis AFB, Nevada, United States, 89191 Less <<
NCT02192528 - Completed - Germany ... More >> Heart & Diabetes Center North-Rhine Westphalia Bad Oeynhausen, NRW, Germany, 32545 Less <<
NCT02152228 Hypoparathyroidism Phase 2 Completed - Israel ... More >> Lin Medical Center Haifa, Israel, 35152 Less <<
NCT00832533 - Completed - United States, New Mexico ... More >> Universtiy of New Mexico - Cancer Center Albuquerque, New Mexico, United States, 87131-0001 Less <<
NCT02438488 - Completed - Austria ... More >> Medical University of Graz Graz, Austria, 8036 Less <<
NCT01757860 Drug Safety H... More >>eart; Disease, Activity Less << Phase 1 Completed - United States, Michigan ... More >> Jasper Clinic Kalamazoo, Michigan, United States, 49007 Less <<
NCT00910260 - Completed - Switzerland ... More >> Dermatology Department, University Hospital Zurich, Switzerland, 8091 Less <<
NCT03451864 - Completed - Egypt ... More >> Kasr Alainy medical school Cairo, Egypt, 12111 Less <<
NCT02517164 - Unknown - France ... More >> University Hospital Recruiting Caen, France, 14000 Contact: Christian Marcelli, MD, PhD    0231063093       Principal Investigator: Christian Marcelli, Professor Less <<
NCT02920502 Inflammation Phase 3 Completed - United States, Ohio ... More >> University Hospitals Cleveland Medical Center Cleveland, Ohio, United States, 44106 Less <<
NCT00798993 End Stage Kidney Disease Phase 4 Completed - Australia, Western Australia ... More >> Sir Charles Gairdner Hospital Perth, Western Australia, Australia, 6009 Less <<
NCT01771380 - Completed - Norway ... More >> University of Tromsø Tromsø, Norway, 9037 Less <<
NCT03499327 Vitamin D3 Deficiency Not Applicable Completed - Germany ... More >> Friedrich-Schiller-University Jena, Thuringia, Germany, 07743 Less <<
NCT02937350 Chronic Kidney Disease Phase 1 Recruiting December 2020 United States, Washington ... More >> University of Washington Recruiting Seattle, Washington, United States, 98195 Contact: Laura Curtin    206-221-3938 Less <<
NCT03104855 Cystic Fibrosis Phase 1 Active, not recruiting December 2019 United States, Washington ... More >> University of Washington Seattle, Washington, United States, 98104 Less <<
NCT00637897 Breast Cancer Phase 1 Completed - United States, North Carolina ... More >> Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 Less <<
NCT01327794 - Completed - United States, New York ... More >> Charles R. Wood Cancer Center at Glens Falls Hospital Glens Falls, New York, United States, 12801 Less <<
NCT01656512 Osteoporosis Phase 3 Completed - Egypt ... More >> Children's Cancer Hospital Egypt 57357 Cairo, Egypt, 11441 Less <<
NCT02549326 Obesity Not Applicable Completed - -
NCT01181531 - Completed - -
NCT01181531 Hyperparathyroidism, Secondary Phase 4 Completed - -
NCT01581996 Chronic Kidney Failure ... More >> End-stage Renal Disease Disorders Associated With Peritoneal Dialysis Less << Not Applicable Completed - United States, California ... More >> Harbor-UCLA Medical Center Torrance, California, United States, 90509 Less <<
NCT03496246 Vitamin D Deficiency ... More >> Inflammatory Bowel Diseases Less << Not Applicable Enrolling by invitation June 2019 Egypt ... More >> Mohammed Ragab Osman Assiut, Egypt Less <<
NCT00630214 Hypocalcemia Phase 2 Completed - Korea, Republic of ... More >> Chungnam National University Hospital Daejeon, Korea, Republic of, 301-040 Less <<
NCT01455181 - Completed - -
NCT01455181 Hypoparathyroidism Phase 3 Completed - Hungary ... More >> Semmelweis University Medical School Budapest, Hungary University of Pécs, School of Medicine Pécs, Hungary University of Szeged Szeged, Hungary Less <<
NCT01793181 - Completed - Sweden ... More >> St Eriks Eye Hospital Stockholm, Sweden, 11282 Less <<
NCT00977080 Chronic Kidney Disease ... More >> Secondary Hyperparathyroidism Hemodialysis Less << Phase 4 Completed - -
NCT01084538 - Completed - Croatia ... More >> Site Reference ID/Investigator# 27525 Dubrovnik, Croatia, 20000 Site Reference ID/Investigator# 27531 Imotski, Croatia, 21260 Site Reference ID/Investigator# 6175 Karlovac, Croatia, 47000 Site Reference ID/Investigator# 27528 Pula, Croatia, 52100 Site Reference ID/Investigator# 27533 Rijeka, Croatia, 51000 Site Reference ID/Investigator# 27524 Sibenik, Croatia, 22000 Site Reference ID/Investigator# 27523 Sisak, Croatia, 44000 Site Reference ID/Investigator# 27529 Slavonski Brod, Croatia, 35000 Site Reference ID/Investigator# 27530 Split, Croatia, 1000 Site Reference ID/Investigator# 27534 Trogir, Croatia, 21220 Site Reference ID/Investigator# 27522 Vinkovci, Croatia, 32000 Site Reference ID/Investigator# 27527 Zadar, Croatia, 23000 Site Reference ID/Investigator# 27526 Zagreb, Croatia, 10000 Site Reference ID/Investigator# 27532 Zagreb, Croatia, 10000 Serbia Site Reference ID/Investigator# 27536 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27538 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27539 Beograd, Serbia, 11000 Site Reference ID/Investigator# 6169 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27540 Beograd, Serbia, 11080 Site Reference ID/Investigator# 27535 Bor, Serbia, 19210 Site Reference ID/Investigator# 27537 Kragujevac, Serbia, 34000 Less <<
NCT00977080 - Completed - -
NCT01765010 Osteoporosis Phase 4 Unknown March 2013 Korea, Republic of ... More >> Seoul National University Medical School Recruiting Seoul, Korea, Republic of, 110-744 Contact: Chan Soo Shin, MD, PhD    82220723734    csshin@snu.ac.kr    Contact: Jung Hee Kim, MD    8220724839    jhkxingfu@gmail.com    Principal Investigator: Chan Soo Shin, MD, PhD Less <<
NCT01084538 - Completed - -
NCT01057186 - Unknown - Norway ... More >> Haukeland University Hospital, Childrens departement Bergen, Norway, 5021 Less <<
NCT01231438 Kidney Failure Phase 2 Completed - Norway ... More >> Oslo Universitetssykehus Rikshospitalet Oslo, Norway, NO-0372 Stavanger University Hospital Stavanger, Norway, NO-4011 Less <<
NCT03183557 Osteoporosis Phase 2 Recruiting June 8, 2022 Japan ... More >> Yukio Nakamura Recruiting Matsumoto, Nagano, Japan, 3908621 Contact: Yukio Nakamura, MD, PhD    +81-263-37-2659    yxn14@aol.jp    Principal Investigator: Yukio Nakamura, MD, PhD Less <<
NCT01524874 Hypovitaminosis D ... More >> Insulin Resistance Diabetes Less << Not Applicable Completed - United States, Hawaii ... More >> Lokahi Health Center Kailua Kona, Hawaii, United States, 96740 United States, Washington Bastyr University Kenmore, Washington, United States, 98028 Less <<
NCT03319251 - Recruiting November 30, 2022 United States, Ohio ... More >> Cleveland Clinic Recruiting Cleveland, Ohio, United States, 44195 Contact: Jeff Negrey, MA    216-636-5504    negreyj2@ccf.org    Contact: Michael Macknin, MD    216-444-5512    MACKNIM@ccf.org Less <<
NCT01896609 Chronic Hepatitis c Phase 4 Unknown June 2015 Egypt ... More >> Faculty of Medicine , Cairo University Recruiting Cairo, Egypt Contact: Rasha Ahmed, MD    +201063432400    rasha7019@yahoo.com    Contact: Moustafa Sameer    +201006016212    msameer@minapharm.com Less <<
NCT03582917 Scoliosis; Adolescence Phase 2 Recruiting September 2021 Greece ... More >> Papanikolaou General Hospital Recruiting Asvestochori, Greece Contact: Lazaros TagKalidis, MD    +30 6977252028    akissdoc@hotmail.com    Department of Physical Medicine and Rehabilitation, University Hospital of Ioannina Recruiting Ioannina, Greece, 45100 Contact: Avraam Ploumis    6932080701    aploumis@uoi.gr Less <<
NCT02306187 Osteoporosis Phase 1 Recruiting December 2019 Japan ... More >> Yukio Nakamura Recruiting Matsumoto, Nagano, Japan, 3908621 Contact: Yukio Nakamura, MD, PhD    +81-263-37-2659    yxn14@aol.jp    Principal Investigator: Yukio Nakamura, MD, PhD Less <<
NCT01774812 Cardiovascular Disease ... More >> Sudden Cardiac Death Less << Phase 2 Completed - Canada, Alberta ... More >> Northland Hemodialysis Clinic Calgary, Alberta, Canada, T2L 2J8 Foothills Medical Centre - University of Calgary Calgary, Alberta, Canada, T2N 2T9 Sheldon M. Chumir Health Centre Calgary, Alberta, Canada, T2R 0X7 Less <<
NCT00640237 Vitamin D Deficiency Phase 3 Unknown August 2008 Israel ... More >> Rambam Health Care Campus Recruiting Haifa, Israel Sub-Investigator: Nodelman Marina, MD Less <<
NCT00165698 Postmenopausal Osteoporosis Phase 3 Completed - China ... More >> Beijing Hospital Beijing, China Chinese PLA General Hospital Beijing, China Peking Union Medical College Hospital Beijing, China Hua Dong Hospital Shanghai, China The Sixth People's Hospital affiliated to Shanghai Jiaopong University Shanghai, China Less <<
NCT00165698 - Completed - -
NCT01894295 Obesity Not Applicable Unknown September 2013 Iran, Islamic Republic of ... More >> TehranUMS Recruiting Tehran, Iran, Islamic Republic of Contact: Mahmoud Jalali, PhD       jalalimahmoud@hotmail.com    Contact: Khadijeh Mirzaei, MS       mina_mirzaei101@yahoo.com Less <<
NCT00144456 Osteoporosis Phase 3 Completed - -
NCT00668330 Systemic Lupus Erythematosus Phase 4 Completed - China ... More >> School of Pharmacy CUHK Hong Kong, China Less <<
NCT03182699 Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Requiring Chronic Dialysis Left Ventricular Hypertrophy Less << Phase 4 Recruiting December 1, 2020 Austria ... More >> Medical University of Vienna Recruiting Vienna, Austria, 1090 Contact: Rainer Oberbauer, Univ.Prof.    004314040043910    rainer.oberbauer@meduniwien.ac.at    Contact: Katharina Doerr, Dr.    004369911966793    Katharina.doerr@meduniwien.ac.at    Wiener Dialysezentrum Recruiting Vienna, Austria, 1220 Contact: Matthias Lorenz, Priv.Doz.    0043 1 908 13 10    matthias.lorenz@dialysewien.at Less <<
NCT02824718 Autosomal Dominant Hypocalcemi... More >>a or OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment Less << Phase 2 Recruiting August 2020 France ... More >> AP-HP hopital Bicetre Not yet recruiting Le Kremlin-Bicetre, Val-de-Marne, France, 94270 Contact: Agnes Linglart, MD       agnes.linglart@aphp.fr    AP-HP Hopital Europeen Georges Pompidou Recruiting Paris, France, 75015 Contact: Anne Blanchard, MD       anne.blanchard@aphp.fr Less <<
NCT02993302 Graves Disease Phase 2 Completed - -
NCT03210688 Minimal Change Disease ... More >> Nephrotic Syndrome Less << Phase 4 Recruiting December 31, 2022 Denmark ... More >> Aarhus University Hospital Recruiting Aarhus, Denmark Contact: Per Ivarsen          Regional Hospital Viborg Recruiting Viborg, Denmark Contact: Tilde Kristensen          Principal Investigator: Tilde Kristensen Less <<
NCT00138983 Rheumatoid Arthritis ... More >> Polymyalgia Rheumatica Giant Cell Arteritis Polymyositis Wegener’s Granulomatosis Less << Phase 3 Completed - Netherlands ... More >> UMC Utrecht Utrecht, Netherlands, 3584 CX Less <<
NCT00483275 Accidental Falls ... More >> Chronic Renal Insufficiency Aged Less << Phase 4 Withdrawn(No final agreement w... More >>ith sponsor) Less << September 2009 Germany ... More >> Klinik für Altersmedizin und Frührehabilitation, Marienhospital, Ruhr-Universität Bochum Herne, NRW, Germany, 44627 Less <<
NCT00828347 Secondary Hyperparathyroidism Not Applicable Completed - Japan ... More >> Kumamoto University Hospital Kumamoto, Japan, 860-8556 Less <<
NCT01020253 Bone Density ... More >>Arthroplasty, Replacement, Hip Less << Not Applicable Unknown - Japan ... More >> Department of orthopaedic surgery, Yokohama City University Yokohama, Kanagawa, Japan Less <<
NCT01974167 Osteoporosis Not Applicable Unknown - Japan ... More >> Nara Hospital Kinki University Faculty of Medicine Recruiting Ikoma, Nara, Japan, 630-0293 Less <<
NCT00469599 Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Vitamin D Deficiency Less << Not Applicable Terminated(Terminated after 86... More >> pt included, because of recruitment problems) Less << - Denmark ... More >> Aalborg University Hospital Aalborg, Denmark, 4000 Århus University Hospital Skejby Aarhus, Denmark, 4000 Hospital of Southwest Denmark Esbjerg Esbjerg, Denmark, 6700 Holbæk County Hospital Holbæk, Denmark, 4300 Holstebro County Hospital Holstebro, Denmark, 7500 Odense University Hospital Odense, Denmark, 5000 Roskilde County Hospital Roskilde, Denmark, 4000 Viborg County Hospital Viborg, Denmark, 8800 Less <<
NCT02747381 Asthma Phase 4 Completed - -
NCT00168909 Osteoporosis, Postmenopausal ... More >> Osteopenia Falls Less << Phase 4 Completed - Germany ... More >> Centre for Muscle and Bone Research, Charité - Campus Benjamin Franklin Berlin, Germany, 12200 Centre for Muscle and Bone Research, Aerpah-Kliniken Esslingen Stuttgart, Germany, 73732 Less <<
NCT01115543 Secondary Hyperparathyroidism ... More >> End Stage Renal Disease Less << Phase 4 Completed - Thailand ... More >> Siriraj Medical School Bangkok-noi, Bangkok, Thailand, 10700 Less <<
NCT01752244 Obesity Not Applicable Unknown January 2013 Iran, Islamic Republic of ... More >> TehranUMS Recruiting Tehran, Iran, Islamic Republic of Contact: Arash Hossein-nezhad, MD, PhD       arashh@bu.edu    Contact: Khadijeh Mirzaei, MS       mirzaei_kh@tums.ac.ir    Principal Investigator: Arash Hossein-nezhad, MD, PhD          Sub-Investigator: Khadijeh Mirzaei, Ms Less <<
NCT00828347 - Completed - -
NCT03147677 Type 2 Diabetic Nephropathy Phase 4 Recruiting December 2018 China, Hunan ... More >> The Third Xiangya Hospital of Central South University Recruiting Changsha, Hunan, China, 410000 Contact: Hao Zhang, Doctor    +86-13975806919    zhanghaoliaoqing@163.com    Hunan Chenzhou NO.1 People's Hospital Recruiting Chenzhou, Hunan, China, 423000 Contact: Xiangpin Liao, bachelor    +81-13507359887    13507359887@139.com    Hunan Yiyang Central Hospital Recruiting Yiyang, Hunan, China, 413000 Contact: Xiaohua Deng, bachelor    +81-13707370981    yoyotyz@126.com Less <<
NCT01364688 Vascular Calcification Phase 2 Unknown December 2012 Thailand ... More >> Faculty of Medicine, Ramathibodi Hospital, Mahidol University Recruiting Phayathai, Bangkok, Thailand, 10400 Contact: Sinee Disthabanchong, MD    +662011116    tesdb@mahidol.ac.th Less <<
NCT03292744 Frail Elderly Syndrome|Elderly... More >> Infection Less << PHASE4 UNKNOWN 2017-12-15 Cipto Mangunkusumo National Ho... More >>spital, Jakarta, Indonesia Less <<
NCT02327091 Muscle Weakness Phase 3 Completed - Indonesia ... More >> Division of Geriatrics, Department of Internal Medicine, University of Indonesia Jakarta Pusat, Jakarta, Indonesia, 10430 Less <<
NCT02895061 Alfacalcidol, Secondary Hyperp... More >>arathyroidism, Hemodialysis Less << COMPLETED 2025-01-16 -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.50mL

0.50mL

0.25mL

12.48mL

2.50mL

1.25mL

24.96mL

4.99mL

2.50mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

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