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Chemical Structure| 1883711-97-4 Chemical Structure| 1883711-97-4

Structure of AM-0902
CAS No.: 1883711-97-4

Chemical Structure| 1883711-97-4

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Potent and selective TRPA1 antagonist (IC50 = 0.02 μM for human TRPA1). Exhibits no siginificant activity against human TRPV1 or TRPV4, and rat TRPV1, TRPV3 or TRPM8. Exhibits efficacy in a rat pain model. Orally bioavailable.

Synonyms: AM-0902

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Product Details of AM-0902

CAS No. :1883711-97-4
Formula : C17H15ClN6O2
M.W : 370.79
SMILES Code : O=C1N(CC2=NC(CCC3=CC=C(Cl)C=C3)=NO2)C=NC4=C1N(C)C=N4
Synonyms :
AM-0902
MDL No. :MFCD31579854
InChI Key :AWJBWNUUODWOKQ-UHFFFAOYSA-N
Pubchem ID :73297271

Safety of AM-0902

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.70mL

0.54mL

0.27mL

13.48mL

2.70mL

1.35mL

26.97mL

5.39mL

2.70mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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