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Chemical Structure| 1883548-84-2 Chemical Structure| 1883548-84-2

Structure of AMG PERK 44
CAS No.: 1883548-84-2

Chemical Structure| 1883548-84-2

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AMG PERK 44 is a highly efficient, selective PERK inhibitor with an IC50 of 6 nM, showing significant cellular selectivity and the ability to induce autophagy, suitable for cancer and metabolic disorder research.

4.5 *For Research Use Only !

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Product Details of AMG PERK 44

CAS No. :1883548-84-2
Formula : C34H29ClN4O2
M.W : 561.07
SMILES Code : O=C1N(N(C(C2=CC=CC=C2)=C1C(C3=CC=C(C(C4=CC=C5N=C(C=CC5=C4)C)=C3N)C)=O)C)C6=CC=CC=C6.[H]Cl
MDL No. :MFCD30182311

Safety of AMG PERK 44

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.78mL

0.36mL

0.18mL

8.91mL

1.78mL

0.89mL

17.82mL

3.56mL

1.78mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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