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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Inaccessible (Haz class 6.1), International USD 150+
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Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 31098-42-7 Chemical Structure| 31098-42-7

Structure of Amifostine thiol
CAS No.: 31098-42-7

Chemical Structure| 31098-42-7

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Amifostine thiol (WR-1065) is the active metabolite of the cell protectant Amifostine. It is a cell protectant with radiation protection capabilities that activate p53 through a JNK-dependent signaling pathway.

Synonyms: WR-1065

4.5 *For Research Use Only !

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Product Details of Amifostine thiol

CAS No. :31098-42-7
Formula : C5H14N2S
M.W : 134.24
SMILES Code : C(CN)CNCCS
Synonyms :
WR-1065
MDL No. :MFCD00296912

Safety of Amifostine thiol

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501
Class:8
UN#:1759
Packing Group:

Isoform Comparison

Biological Activity

Description
Amifostine thiol (WR-1065), an active metabolite of the cytoprotector Amifostine, exhibits cytoprotective and radioprotective properties. It activates p53 through a JNK-dependent signaling pathway [1][2][3].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

7.45mL

1.49mL

0.74mL

37.25mL

7.45mL

3.72mL

74.49mL

14.90mL

7.45mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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