Structure of Amiodarone HCl
CAS No.: 19774-82-4
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Amiodarone HCl is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM.
Synonyms: Amiodarone (hydrochloride); Amiodarone hydrochloride
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CAS No. : | 19774-82-4 |
Formula : | C25H30ClI2NO3 |
M.W : | 681.77 |
SMILES Code : | CCCCC1=C(C(C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)=O)C3=C(O1)C=CC=C3.Cl |
Synonyms : |
Amiodarone (hydrochloride); Amiodarone hydrochloride
|
MDL No. : | MFCD00069204 |
InChI Key : | ITPDYQOUSLNIHG-UHFFFAOYSA-N |
Pubchem ID : | 441325 |
GHS Pictogram: |
![]() ![]() |
Signal Word: | Warning |
Hazard Statements: | H303-H373-H312+H332-H361 |
Precautionary Statements: | P201-P202-P260-P270-P271-P281-P302+P352-P304+P340-P312-P363-P403-P501 |
Target |
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In Vitro:
Concentration | Treated Time | Description | References |
CAFs | 2.5 μM | 24 h | To evaluate the effect of Amiodarone on the activated state of CAFs, results showed that Amiodarone partially reversed the activated state of CAFs and reduced the protumor effects of CAFs on PCa cell growth. | PMC11165820 |
DU145 cells | 2.5 μM | 24 h | To evaluate the effect of Amiodarone on the growth of DU145 cells, results showed that Amiodarone reduced the protumor effects of CAFs on DU145 cell growth. | PMC11165820 |
BEAS-2B cells | 1, 3, 9 μM | 24 h | Amiodarone significantly decreased the viability of BEAS-2B cells, increased LDH release, ROS generation, caspase 3 activation, and apoptosis. | PMC11731350 |
BEAS-2B cells | 3 μM | 24 h | Amiodarone significantly induced ROS generation and mitochondrial membrane potential depolarization in BEAS-2B cells, while artemisinin pretreatment significantly inhibited these effects. | PMC11731350 |
BEAS-2B cells | 3 μM | 24 h | Amiodarone significantly increased caspase 3 activity and apoptosis in BEAS-2B cells, while artemisinin pretreatment significantly inhibited these effects. | PMC11731350 |
RAW 264.7 cells | 0.312 μM | 1, 3, 5, 7 days | To investigate the effect of amiodarone on BMP accumulation in RAW 264.7 cells, the results showed that amiodarone treatment significantly increased cellular BMP levels. | PMC11277439 |
NR8383 rat alveolar macrophages | 5 µM | 24 h | To evaluate the effects of Amiodarone on macrophage morphology and function, the results showed that amiodarone-induced foamy macrophages displayed characteristics of proinflammatory macrophages, including significantly increased nitric oxide production, vacuolation and lipidosis, and decreased phagocytic activity. | PMC8440860 |
A549 cells | 5 μM | 24 h | Test whether Amiodarone induces phospholipidosis, results showed Amiodarone significantly induced NBD-PE fluorescence, while sangivamycin did not. | PMC8765048 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Mice | C57BL/6J mice | Oral | 300 mg/kg | 5 times per week for 4 weeks | To study the amiodarone-induced interstitial lung disease (ILD) model, results showed that amiodarone caused a gradual decrease in in mice, with macrophage infiltration observed in the lungs, while co-treatment with dabigatran significantly attenuated these changes. | PMC8490809 |
SCID mice | PCa xenograft model | Intratumoral injection | 250 μl | 5 consecutive days for 2 weeks | To evaluate the effect of Amiodarone on the growth of PCa xenograft tumors, results showed that Amiodarone reduced the protumor effects of CAFs on tumor growth. | PMC11165820 |
Mice | Awake and freely moving CD-1 male mice | Intraperitoneal injection | 5 mg/kg | Single administration, observed for 6 hours | Amiodarone did not revert the JWH-018-induced bradycardia but reduced tachyarrhythmic events, completely suppressing them during the last three hours of the experiment. Additionally, amiodarone slightly reverted the JWH-018-induced vasoconstriction during the fourth hour and restored the breathing rate reduction caused by JWH-018. | PMC10142259 |
C57Bl6/J mice | Amiodarone-induced lung injury model | tracheal injection | 3 mg/kg | single injection | Amiodarone significantly increased TUNEL-positive cells and cleaved caspase 3 protein levels in the lung tissue of mice, while artemisinin pretreatment significantly inhibited these effects and increased p-AMPK and Nrf2 protein levels. | PMC11731350 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02814903 | - | Unknown | August 2017 | France ... More >> Joachim ALEXANDRE Recruiting Caen, Basse Normandie, France, 14000 Contact: Mathieu CHEQUEL, MD +33625342363 chequel-m@chu-caen.fr Contact: Pierre OLLITRAULT, MD +33624922671 ollitrault-p@chu-caen.fr Less << | |
NCT03685149 | Arrhythmogenic Right Ventricul... More >>ar Cardiomyopathy Less << | Phase 2 | Not yet recruiting | August 2020 | United States, New York ... More >> University of Rochester Medical Center Not yet recruiting Rochester, New York, United States, 14642 Contact: Spencer Rosero, MD 585-275-4775 spencer_rosero@urmc.rochester.edu Contact: Laura Wing 585-273-4128 laura_wing@urmc.rochester.edu Less << |
NCT00589303 | - | Terminated(Lack of funding) | - | - | |
NCT00589303 | Atrial Fibrillation ... More >> Heart Failure Less << | Phase 3 | Terminated(Lack of funding) | - | United States, Arizona ... More >> Mayo Clinic Arizona Scottsdale, Arizona, United States, 85259 United States, Indiana The Heart Group Evansville, Indiana, United States, 47710 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Oregon Oregon Health and Science University Portland, Oregon, United States, 97239 United States, Tennessee Chattanooga Heart Institute Chattanooga, Tennessee, United States, 37404 Canada, Alberta University of Calgary and Calgary Health Region Calgary, Alberta, Canada, T2N-4N1 Less << |
NCT02248753 | Atrial Fibrillation | Not Applicable | Active, not recruiting | October 2019 | Netherlands ... More >> VU University Medical Center Amsterdam, Netherlands Amphia Hospital Breda, Netherlands Catharina Ziekenhuis Eindhoven, Netherlands Medisch Spectrum Twente Enschede, Netherlands University Medical Center Groningen Groningen, Netherlands Zuyderland Medical Center Heerlen, Netherlands Alrijne Hospital Leiderdorp, Netherlands Maastricht University Medical Center Maastricht, Netherlands St. Antonius Hospital Nieuwegein, Netherlands Franciscus Gasthuis Rotterdam, Netherlands Antonius Ziekenhuis Sneek, Netherlands HagaZiekenhuis The Hague, Netherlands St. Elisabeth - TweeSteden Hospital Tilburg, Netherlands Diakonessenhuis Utrecht, Netherlands VieCuri Medical Center Venlo, Netherlands Less << |
NCT01856075 | - | Completed | - | Germany ... More >> Praxis fuer Kardiologie, Im Muehlenbach 2B Bonn, Germany, 53127 Less << | |
NCT01742039 | - | Completed | - | United States, District of Col... More >>umbia George Washington University Hospital Washington DC, District of Columbia, United States, 20037 George Washington University Washington, District of Columbia, United States, 20037 Less << | |
NCT00392106 | Atrial Fibrillation | Phase 3 | Suspended(voluntarily by Spons... More >>or to investigate an anticipated SAE) Less << | June 2011 | - |
NCT02294955 | Atrial Fibrillation ... More >> Quality of Life Less << | Not Applicable | Active, not recruiting | September 2018 | Sweden ... More >> Carina Blomström Lundqvist Uppsala, Sweden, S-75185 Less << |
NCT00000531 | Arrhythmia Ca... More >>rdiovascular Diseases Death, Sudden, Cardiac Heart Diseases Tachycardia, Ventricular Ventricular Fibrillation Less << | Phase 3 | Completed | - | - |
NCT01411371 | Atrial Fibrillation ... More >> Heart Failure Less << | Not Applicable | Unknown | October 2011 | United Kingdom ... More >> Barts & The London NHS Trust Recruiting London, UK, United Kingdom, EC1A 7BE Contact: Ross J Hunter, MRCP 442076018639 ross.hunter@bartsandthelondon.nhs.uk Principal Investigator: Richard J Schilling, MD FRCP Sub-Investigator: Ross J Hunter, MRCP Less << |
NCT01430806 | ICD ICD SHOCK... More >>S DRONEDARONE Less << | Not Applicable | Unknown | December 2015 | - |
NCT00920244 | - | Completed | - | Norway ... More >> St.Olavs Hospital, Department of Anesthesia Trondheim, Norway, 7014 Less << | |
NCT01058837 | - | Unknown | August 2011 | United States, Washington ... More >> Seattle Institute for Cardiac Research Bellevue, Washington, United States, 98004-2206 Less << | |
NCT01341353 | Atrial Fibrillation | Phase 4 | Unknown | December 2015 | China, Hubei ... More >> Renmin Hospital of Wuhan University Recruiting Wuhan, Hubei, China Contact: Cong xin Huang, doctor 13907131546 huangcongxin@yahoo.com.cn Principal Investigator: cong xin Huang, doctor Less << |
NCT01181414 | Chronic Heart Failure ... More >> Cardiomyopathy, Dilated Atrial Fibrillation Less << | Phase 4 | Completed | - | Spain ... More >> Hospital Clinic de Barcelona Barcelona, Spain, 08036 Less << |
NCT02389218 | Atrial Fibrillation | Phase 4 | Recruiting | March 2020 | Belgium ... More >> Brussels Heart Centre Recruiting Brussels, Belgium, 1000 Contact: Luc Jordaens, MD +3228910961 ljordaens@clstjean.be Contact: Peter Goethals, MD +3228910961 pgoethals@clstjean.be Saint Luc Recruiting Brussels, Belgium Contact: Jean-Benoit Le Polain De Waroux, MD, PhD +3227642888 jblpdw@hotmail.com Dept Cardiologie Recruiting Gent, Belgium, 9000 Contact: Frederic Van Heuverswyn, MD +3293323459 Frederic.VanHeuverswyn@uzgent.be Contact: Luc Jordaens, MD, Phd +3293323459 l.jordaens@gmail.com Less << |
NCT00540787 | Paroxysmal Atrial Fibrillation | Phase 4 | Completed | - | United States, Alabama ... More >> University of Alabama, Birmingham Birmingham, Alabama, United States, 35294 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Ohio Mid-Ohio Cardiology Columbus, Ohio, United States, 43214 France Hôpital Haut Lèvêque Pessac, Paris, France Hopital Lariboisiere Paris, France, 75010 Switzerland Hopital Cantonal de Geneve Geneva, Switzerland, 12111 Less << |
NCT00121524 | Cardiac Arrest | Phase 2 | Completed | - | Norway ... More >> Ulleval University Hospital Oslo, Norway, N-0407 Less << |
NCT01566344 | Heart Diseases ... More >> Cardiac Arrhythmias Ventricular Premature Complexes Systolic Heart Failure Cardiomyopathies Less << | Not Applicable | Unknown | December 2016 | Netherlands ... More >> Maastricht University Medical Centre Recruiting Maastricht, Limburg, Netherlands, 6202 AZ Contact: Masih Mafi Rad, MD +31-43-3871613 masih.mafirad@mumc.nl Contact: Yuri Blaauw, MD, PhD +31-43-3877095 yuri.blaauw@mumc.nl Sub-Investigator: Masih Mafi Rad, MD Less << |
NCT00721032 | Ventricular Tachycardia | Not Applicable | Withdrawn(PI left the institut... More >>ion) Less << | August 2015 | United States, Oregon ... More >> Oregon Health & Science University Portland, Oregon, United States, 97239 Less << |
NCT03528616 | - | Not yet recruiting | November 30, 2019 | - | |
NCT01709682 | Paroxysmal Atrial Fibrillation... More >> Failed First Radiofrequency Ablation Procedure Less << | Phase 2 | Completed | - | Russian Federation ... More >> State Research Institute of Circulation Pathology Novosibirsk, Russian Federation, 630055 Less << |
NCT01198275 | Atrial Fibrillation | Phase 3 | Completed | - | Italy ... More >> Arrhytmias and Heart failure Unit-Spedali Civili Hospital Brescia, Italy, 25100 Less << |
NCT01511263 | Primary Amyloidosis of Light C... More >>hain Type Less << | Phase 2 | Terminated | - | Italy ... More >> Centro per lo Studio e la Cura delle Amiloidosi Sistemiche - Fondazione IRCCS Policlinico S.Matteo Pavia, Italy, 27100 Less << |
NCT01013688 | Rheumatic Valve Disease ... More >> Atrial Fibrillation Less << | Phase 3 | Unknown | May 2010 | China ... More >> Fuwai cardiovascular disease hospital Recruiting Beijing, China, 100037 Contact: Wangxin , MD 86 10 15810210252 liuyedao21st@hotmail.com Less << |
NCT02830360 | Ventricular Tachycardia (VT) | Phase 4 | Recruiting | October 2022 | Canada, Nova Scotia ... More >> Nova Scotia Health Authority Recruiting Halifax, Nova Scotia, Canada, B3H 3A7 Contact: Karen Giddens 902 473 2758 karen.giddens@nshealth.ca Principal Investigator: John L Sapp, MD FRCPC Less << |
NCT01576042 | Ventricular Tachycardia | Not Applicable | Terminated(Main objectives of ... More >>the study were met; consensus among investigators that continuing the study would not add new information beyond that already learned.) Less << | - | United States, Maryland ... More >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio Ohio State University Medical Center Columbus, Ohio, United States, 43210 United States, Pennsylvania Penn State Milton S. Hershey Medical Center Hershey, Pennsylvania, United States, 17033 University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15237 Less << |
NCT00905853 | Recurrent Ventricular Tachycar... More >>dia Less << | Phase 4 | Completed | - | Canada, Nova Scotia ... More >> QEII Health Sciences Centre Halifax, Nova Scotia, Canada, B3H 3A7 Less << |
NCT01198275 | - | Completed | - | - | |
NCT01798277 | Ventricular Tachycardia ... More >> Coronary Artery Disease Less << | Phase 3 | Withdrawn(Low Enrolment) | December 2015 | - |
NCT02303639 | Myocardial Infarction ... More >> Ventricular Tachyarrhythmia Less << | Phase 4 | Unknown | June 2018 | Finland ... More >> Central Finland Central Hospital Recruiting Jyväskylä, Finland Heart Center Tampere University Hospital Recruiting Tampere, Finland Contact: Heikki Mäkynen, MD Less << |
NCT00000609 | Arrhythmia Ca... More >>rdiovascular Diseases Death, Sudden, Cardiac Heart Diseases Heart Failure, Congestive Heart Failure Less << | Phase 3 | Completed | - | - |
NCT00000464 | Arrhythmia Ca... More >>rdiovascular Diseases Heart Arrest Heart Diseases Myocardial Infarction Ventricular Fibrillation Less << | Phase 3 | Completed | - | - |
NCT01576042 | - | Terminated(Main objectives of ... More >>the study were met; consensus among investigators that continuing the study would not add new information beyond that already learned.) Less << | - | - | |
NCT02132767 | Postoperative Atrial Fibrillat... More >>ion Less << | Phase 3 | Completed | - | - |
NCT03734562 | Monomorphic Ventricular Tachyc... More >>ardia Less << | Not Applicable | Completed | - | Spain ... More >> Hospital General UNiversitario Gregorio Marañon Madrid, Spain, 28009 Less << |
NCT01850277 | Atrial Fibrillation ... More >> Heart Failure Less << | Phase 4 | Unknown | March 2017 | Poland ... More >> Institute of Cardiology, II Dept. of Coronary Heart Disease Recruiting Warsaw, Poland, 02-637 Contact: Jan B Ciszewski, MD 223434050 ext +48 jciszewski@ikard.pl Principal Investigator: Jan B Ciszewski, MD Less << |
NCT00233441 | Atrial Fibrillation ... More >> Atrial Flutter Less << | Phase 2 Phase 3 | Completed | - | - |
NCT02114528 | Ventricular Tachycardia ... More >> Ventricular Arrhythmia Less << | Phase 4 | Terminated(Low recruitment. Pi... More >>lot trial.) Less << | - | Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Less << |
NCT00257959 | Ventricular Tachycardia | Phase 4 | Completed | - | Canada, Ontario ... More >> McMaster University Hamilton, Ontario, Canada Less << |
NCT00272636 | Atrial Fibrillation | Not Applicable | Completed | - | United States, Michigan ... More >> University of Michigan Health System Ann Arbor, Michigan, United States, 48109 Italy San Raffaele Hospital Milan, Italy Less << |
NCT02145546 | Atrial Fibrillation | Phase 4 | Unknown | May 2017 | China, Shanghai ... More >> Xinhua Hospital, Shanghai Jiao Tong University School of Medicne Not yet recruiting Shanghai, Shanghai, China, 200092 Principal Investigator: Yi-Gang Li, MD Less << |
NCT01140581 | Atrial Fibrillation | Phase 4 | Completed | - | - |
NCT02132767 | - | Completed | - | - | |
NCT00287209 | Atrial Fibrillation ... More >> Coronary Artery Bypass Grafting Less << | Phase 4 | Completed | - | Denmark ... More >> Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine, Skejby Sygehus, Aarhus University Hospital Aarhus N, Denmark, 8200 Less << |
NCT01229254 | Atrial Fibrillation ... More >> Atrial Flutter Less << | Phase 2 | Completed | - | - |
NCT00007605 | Atrial Fibrillation ... More >> Cerebrovascular Accident Death, Sudden Less << | Phase 3 | Completed | - | - |
NCT01229254 | - | Completed | - | - | |
NCT03228823 | Ventricular Premature Beats, C... More >>ontractions, or Systoles Cardiomyopathies Less << | Phase 4 | Not yet recruiting | August 31, 2020 | United States, California ... More >> University of California, San Francisco Not yet recruiting San Francisco, California, United States, 94143 Contact: Edward Gerstenfeld, M.D. 415-476-5706 edward.gerstenfeld@ucsf.edu Principal Investigator: Edward Gerstenfeld, M.D. Principal Investigator: Teresa DeMarco, M.D. United States, Virginia McGuire VA Medical Center Not yet recruiting Richmond, Virginia, United States, 23249 Contact: Jose F Huizar, M.D. 804-675-5466 jose.huizar2@va.gov Contact: Donna Sargent, R.N.. 804-675-5466 donna.sargent@va.gov Principal Investigator: Jose F Huizar, M.D. Sub-Investigator: Karoly Kaszala, M.D., Ph.D. Sub-Investigator: Alex Y Tan, M.D. Virginia Commonwealth University Not yet recruiting Richmond, Virginia, United States, 23298 Contact: Kenneth A Ellenbogen, M.D. 804-628-0147 kenneth.Ellenbogen@vcuhealth.org Principal Investigator: Kenneth A Ellenbogen, M.D. Principal Investigator: Adam Sima, Ph.D. Canada, Alberta Libin Cardiovascular Institute, University of Calgary Not yet recruiting Calgary, Alberta, Canada, T2N 2T9 Contact: Carlos A Morillo, M.D. 403-944-2670 carlos.morillo@ucalgary.ca Principal Investigator: Carlos A Morillo, M.D. Less << |
NCT01461733 | Atrial Fibrillation | Phase 4 | Completed | - | - |
NCT01955759 | Patients With Coronary Artery ... More >>Disease Scheduled for by Pass Surgery Less << | Early Phase 1 | Unknown | February 2015 | Bosnia and Herzegovina ... More >> Heart Center BH Not yet recruiting Tuzla, TK, Bosnia and Herzegovina, 75000 Contact: Enes Osmanović +387 66 725 744 osmanovic@bih.net.ba Less << |
NCT03715556 | Sepsis Septic... More >> Shock Atrial Fibrillation Ventricular Fibrillation Atrial Fibrillation Rapid Less << | Phase 3 | Not yet recruiting | December 1, 2021 | Brazil ... More >> Instituto do Coração - HMFMUSP São Paulo, Brazil, 05403000 Less << |
NCT00127712 | Atrial Fibrillation | Phase 4 | Completed | - | United States, Indiana ... More >> Indiana University Indianapolis, Indiana, United States, 46202 Less << |
NCT01461733 | - | Completed | - | - | |
NCT00127712 | - | Completed | - | - | |
NCT03244748 | - | Recruiting | March 1, 2018 | Turkey ... More >> Turkiye Yuksek Ihtisas Training and Research Hospital Recruiting Ankara, Turkey, 06590 Contact: Firat Ozcan, Ass. Prof, MD 5327854000 drfozcan@gmail.com Less << | |
NCT01199081 | Atrial Fibrillation | Phase 4 | Completed | - | - |
NCT00420017 | Atrial Fibrillation ... More >> Esophagectomy Less << | Phase 4 | Completed | - | United States, Indiana ... More >> Indiana University Hospital Indianapolis, Indiana, United States, 46202 Less << |
NCT01480336 | Arrhythmia | Not Applicable | Completed | - | United States, Connecticut ... More >> Hartford Hospital Hartford, Connecticut, United States, 06102 Less << |
NCT00953212 | - | Completed | - | - | |
NCT01558830 | Chronic Stable Angina ... More >> Coronary Artery Disease Atrial Fibrillation Ventricular Tachycardia Less << | Phase 4 | Unknown | July 2013 | United States, Nevada ... More >> Cardiovascular Consultants of Nevada Recruiting Henderson, Nevada, United States, 89052 Cardiovascular Consultants of Nevada Recruiting Las Vegas, Nevada, United States, 89144 Cardiovascular Consultants of Nevada Recruiting Las Vegas, Nevada, United States, 89196 Less << |
NCT03029169 | Supraventricular Arrhythmia ... More >> Septic Shock Less << | Phase 4 | Recruiting | October 2020 | Czechia ... More >> Dept. Anaesthesia and Intensive Care, 3rd Medical Faculty, Charles University Recruiting Prague 10, Czechia, 100 34 Contact: Petr Waldauf, MD +420267163410 petrwaldauf@gmail.com Dept of Anaesthesia and Intensive Care, General University Hospital, 1st Medical Faculty, Charles University Recruiting Prague 2, Czechia, 128 08 Contact: Martin Balik, A/Prof +420224963366 martin.balik@vfn.cz Principal Investigator: Martin Balik, MD, PhD Less << |
NCT00383799 | Ventricular Tachycardia ... More >> Wide QRS Tachycardia Less << | Phase 4 | Terminated(Steering Committee ... More >>decision after inclusion of 74 patients after 6 years and very slow inclusion rate) Less << | - | Spain ... More >> Hospital El Escorial El Escorial, Madrid, Spain Hospital Universitario de Getafe Getafe, Madrid, Spain Hospital Santa María del Rosell Cartagena, Murcia, Spain Fundación Hospitalaria de Cieza Cieza, Murcia, Spain Hospital Los Arcos San Javier, Murcia, Spain Hospital General Alicante, Spain Hospital Clinic Barcelona, Spain Hospital Vall d'Hebron Barcelona, Spain Hospital de Basurto Bilbao, Spain Hospital San Cecilio Granada, Spain Hospital Virgen de las Nieves Granada, Spain Hospital General Universitario Gregorio Marañón Madrid, Spain, 28007 Hospital 12 de Octubre Madrid, Spain Hospital Clínico San Carlos Madrid, Spain Hospital de La Princesa Madrid, Spain Hospital de Móstoles Madrid, Spain Hospital General Universitario La Paz Madrid, Spain Hospital Puerta de Hierro Madrid, Spain Hospital Carlos Haya Malaga, Spain Hospital Virgen de la Arrixaca Murcia, Spain Hospital Clínico Virgen de la Victoria Málaga, Spain Hospital de Son Dureta Palma de Mallorca, Spain Hospital de Son Llatzer Palma de Mallorca, Spain Hospital de Donostia San Sebastián, Spain Hospital de Valme Sevilla, Spain Hospital Universitario Virgen del Rocío Sevilla, Spain Hospital Virgen de la Salud Toledo, Spain Hopital Clínico Universitario Valencia, Spain Hospital Río Hortega Valladolid, Spain Less << |
NCT00420953 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... More >> Anapharm Montreal, Quebec, Canada Less << |
NCT00953212 | Atrial Fibrillation ... More >> Atrial Flutter Less << | Phase 3 | Completed | - | United States, Maine ... More >> Maine Medical Center Portland, Maine, United States, 04102 Less << |
NCT00251706 | Atrial Fibrillation | Phase 3 | Completed | - | Canada, Alberta ... More >> Libin Cardiovascular Institute / University of Calgary Calgary, Alberta, Canada, T2N 2T9 Less << |
NCT02301390 | Ventricular Tachycardia | Not Applicable | Terminated(could not meet enro... More >>llment goal) Less << | - | India ... More >> CARE Institute of Medical Science Ahmedabad, India CARE Hospital Hyderabad, India Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry, India Less << |
NCT00826826 | Atrial Fibrillation | Not Applicable | Completed | - | Denmark ... More >> Rigshospitalet Copenhagen, Denmark, 2100 Gentofte University Hospital Hellerup, Denmark, 2900 Less << |
NCT00420017 | - | Completed | - | - | |
NCT02715687 | Atrial Fibrillation | Phase 3 | Unknown | December 2018 | - |
NCT01649544 | Mitral Valvulopathy ... More >> Atrial Fibrillation Less << | Not Applicable | Terminated(End of commercializ... More >>ation of the medical device) Less << | - | France ... More >> CHU de Grenoble Grenoble, France Hospices Civiles de Lyon Lyon, France CHU de Montpellier Montpellier, France CHU de Rennes Rennes, France CHU de Saint-Etienne Saint-etienne, France Less << |
NCT00392431 | Persistant Atrial Fibrillation | Not Applicable | Completed | - | Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands, 9700RB Less << |
NCT02171026 | Healthy | Phase 1 | Completed | - | - |
NCT00993382 | Arrhythmia Prophylaxis ... More >> Ventricular Arrhythmia Less << | Phase 2 | Completed | - | - |
NCT00739193 | Blood Pressure | Phase 2 | Withdrawn | December 2008 | - |
NCT00784316 | Atrial Fibrillation ... More >> Cardiac Surgery Less << | Phase 4 | Completed | - | Finland ... More >> Halonen jari Kuopio, Finland, FIN- 70211 Less << |
NCT03720210 | Amiodarone-Induced Thyrotoxico... More >>sis Less << | Not Applicable | Recruiting | July 2020 | United States, Minnesota ... More >> Mayo Clinic in Rochester Recruiting Rochester, Minnesota, United States, 55905 Contact: Marius Stan, MD 507-284-2463 Stan.Marius@mayo.edu Contact: Vishakantha (Vishu) Murthy, PhD 507-255-8112 Murthy.Vishakantha@mayo.edu Less << |
NCT00729911 | Heart Failure | Phase 4 | Active, not recruiting | December 2018 | United States, Texas ... More >> Texas Cardiac Arrhythmia Research Foundation Austin, Texas, United States, 78758 Less << |
NCT00654290 | Atrial Fibrillation | Not Applicable | Completed | - | Iran, Islamic Republic of ... More >> Shiraz University of Medical Sciences/Cardiac Surgery and Cardiology Ward/Namazi and Shahid Faghihi Hospital Shiraz, Fars, Iran, Islamic Republic of, 71345 Less << |
NCT01401647 | Cardiac Arrest | Phase 3 | Completed | - | United States, Alabama ... More >> Alabama Resuscitation Center Birmingham, Alabama, United States, 35294 United States, California UCSD-San Diego Resuscitation Center San Diego, California, United States, 92103 United States, Oregon Portland Resuscitation Outcomes Consortium, Oregon Health & Sciences University Portland, Oregon, United States, 97239 United States, Pennsylvania The Pittsburgh Resuscitation Network, University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15261 United States, Texas Dallas Center for Resuscitation Research, University of Texas Southwestern Medical Center Dallas, Texas, United States, 75390 United States, Washington Seattle-King County Center for Resuscitation Research, University of Washington Seattle, Washington, United States, 98195 United States, Wisconsin Milwaukee Resuscitation Network, Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Canada, Ontario University of Ottawa/University of British Columbia Collaborative RCC, Ottawa Health Research Ottawa, Ontario, Canada Toronto Regional Resuscitation Research Out-of-Hospital Network, University of Toronto Toronto, Ontario, Canada Less << |
NCT01401647 | - | Completed | - | - | |
NCT01416935 | Atrial Fibrillation | Not Applicable | Unknown | July 2016 | United States, Virginia ... More >> Inova Fairfax Hospital Falls Church, Virginia, United States, 22042 Less << |
NCT00587483 | Other Intraoperative Cardiac F... More >>unctional Disturbances During Cardiac Surgery Less << | Not Applicable | Completed | - | United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less << |
NCT00587483 | - | Completed | - | - | |
NCT01627106 | Atrial Fibrillation | Phase 4 | Withdrawn | March 2016 | - |
NCT00489736 | Atrial Fibrillation | Phase 3 | Completed | - | - |
NCT01276093 | Atrial Fibrillation | Not Applicable | Terminated(DSMB recommendation... More >>; enrollment too slow) Less << | March 2016 | Netherlands ... More >> Elkerliek Hospital Helmond, Noord Brabant, Netherlands Maxima Medical Center Veldhoven, Noord Brabant, Netherlands, 5504DB Haga Hospital Den Haag, Zuid Holland, Netherlands, 2545 CH Onze Lieve Vrouwen Gasthuis Amsterdam, Netherlands, 1091 AC Catharina Ziekenhuis Eindhoven, Netherlands, 5623 EJ Medisch Spectrum Twente Enschede, Netherlands, 7513 ER Less << |
NCT02750319 | Thoracic Surgery ... More >> Atrial Fibrillation in High Risk Patients Less << | Phase 3 | Recruiting | April 2019 | United States, Missouri ... More >> University of Washington School of Medicine in St. Louis Recruiting Saint Louis, Missouri, United States, 63110 Contact: Bryan Meyers, MD 314-362-4533 Principal Investigator: Bryan Meyers, MD United States, New Jersey Memoral Sloan Kettering Basking Ridge (Consent only) Recruiting Basking Ridge, New Jersey, United States Contact: David Amar, MD 212-639-6798 Memorial Sloan Kettering Monmouth (Consent only) Recruiting Middletown, New Jersey, United States, 07748 Contact: David Amar, MD 212-639-6798 Memorial Sloan Kettering Bergen (Consent only) Recruiting Montvale, New Jersey, United States, 07645 Contact: David Amar, MD 212-639-6798 United States, New York Memorial Sloan Kettering Commack (Consent only) Recruiting Commack, New York, United States, 11725 Contact: David Amar, MD 212-639-6798 Memorial Sloan Kettering Westchester (Consent only) Recruiting Harrison, New York, United States, 10604 Contact: David Amar, MD 212-639-6798 Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: David Amar, MD 212-639-6798 Contact: David R Jones, MD 212-639-6428 Principal Investigator: David Amar, MD Memorial Sloan Kettering Rockville Centre (Consent only) Recruiting Rockville Centre, New York, United States, 11570 Contact: David Amar, MD 212-639-6798 Less << |
NCT00489736 | - | Completed | - | - | |
NCT02307591 | Ebola Virus Disease | Phase 2 Phase 3 | Withdrawn(The Study could not ... More >>be started due to an insufficient number of new EVD cases.) Less << | - | - |
NCT01266681 | Atrial Fibrillation | Not Applicable | Unknown | - | United Kingdom ... More >> Eastbourne General Hospital Not yet recruiting Eastbourne, East Sussex, United Kingdom, BN21 2UD Sub-Investigator: Oliver Waller, Bsc (hons) Less << |
NCT00668759 | Atrial Fibrillation | Phase 3 | Completed | - | - |
NCT03153072 | Supraventricular Tachycardia | Phase 2 | Withdrawn(decision of the inve... More >>stigator) Less << | - | France ... More >> CHU Amiens Picardie Amiens, Picardie, France, 80054 Less << |
NCT00724581 | Atrial Fibrillation | Phase 4 | Unknown | December 2009 | Denmark ... More >> Aarhus University Hospital, Skejby Not yet recruiting Aarhus, Denmark, DK-8200 Contact: Lars R Zebis, MD, Ph.D. +45 89495566 lrz@post.tele.dk Contact: Thomas D Christensen, MD, Ph.D. +45 89495566 Principal Investigator: Lars R Zebis, MD, Ph.D. Less << |
NCT00313443 | - | Completed | - | - | |
NCT00313443 | Arrhythmia At... More >>rial Fibrillation Atrial Flutter Less << | Phase 4 | Completed | - | France ... More >> Hopital Lariboisiere, Internal Medicine "A" and Cardiology Services Paris, France, 75010 Less << |
NCT02341105 | Atrial Fibrillation | Phase 4 | Unknown | November 2017 | Canada, Ontario ... More >> Hamilton Health Sciences Recruiting Hamilton, Ontario, Canada, L8L 2X2 Contact: Guy Amit, MD 905-527-4322 ext 40453 Less << |
NCT00300495 | - | Terminated(Unable to accrual t... More >>otal number of participants during study period.) Less << | - | - | |
NCT01422148 | Atrial Fibrillation | Not Applicable | Recruiting | January 2020 | United States, Massachusetts ... More >> Baystate Medical Center Recruiting Springfield, Massachusetts, United States, 01107 Contact: Barbara Burkott, BN, BSNCCRP 413-794-0000 ext 1305 barbara.burkott@baystatehealth.org Less << |
NCT00300495 | Atrial Fibrillation ... More >> Lung Cancer Less << | Phase 3 | Terminated(Unable to accrual t... More >>otal number of participants during study period.) Less << | - | United States, Massachusetts ... More >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 Less << |
NCT03299517 | Arrhythmias Ventricular | Phase 4 | Recruiting | August 2, 2022 | Brazil ... More >> Instituto do Coração - HMFMUSP Recruiting São Paulo, SP, Brazil, 05403000 Contact: Alexandre Soeiro, MD 5511-2661-5299 alexandre.soeiro@bol.com.br Less << |
NCT01722942 | Chagas Cardiomyopathy ... More >> Non-sustained Ventricular Tachycardia At Least 10 Points in Rassi Risk Score for Death Less << | Not Applicable | Not yet recruiting | October 2019 | Brazil ... More >> Hospital Ana Nery Not yet recruiting Salvador, BA, Brazil Contact: Luiz P Magalhães, MD luizpmagalhaes@uol.com.br Contact: Alexandro A Fagundes, MD alexfagundes@cardiol.br Principal Investigator: Luiz P Magalhães, MD Sub-Investigator: Alexsandro A Fagundes, MD Santa Casa de Salvador Not yet recruiting Salvador, BA, Brazil Contact: Ricardo E Pereira, MD rickeloy@terra.com.br Principal Investigator: Ricardo E Pereira, MD Hospital de Messejana Not yet recruiting Fortaleza, CE, Brazil Contact: João D Souza Neto, MD jdsneto@cardiol.br Contact: Stela MV Sampaio, MD stelavsampaio@terra.com.br Principal Investigator: João D Souza Neto, MD Sub-Investigator: Stela MV Sampaio, MD Hospital Universitário Walter Cantideo Not yet recruiting Fortaleza, CE, Brazil Contact: Francisca TM Pereira, MD tatianap@baydenet.com.br Contact: Eduardo A Rocha, MD eduardoa@cardiol.br Principal Investigator: Francisca TM Pereira, MD Sub-Investigator: Eduardo A Rocha, MD Sub-Investigator: Marcelo P Monteiro, MD Hospital de Base Not yet recruiting Brasilia, DF, Brazil Contact: Ayrton K Peres, MD, PhD ayrton.ritmocardio@gmail.com Contact: Tamer N Seixas, MD, PhD tamersn@cardiol.br Principal Investigator: Ayrton K Peres, MD, PhD Sub-Investigator: Thamer N Seixas, MD, PhD Sub-Investigator: Edna MM Oliveira, MD Sub-Investigator: Marcus VN Santos, MD Sub-Investigator: Romeu Mello Neto, MD Instituto de Cardiologia do Distrito Federal Not yet recruiting Brasilia, DF, Brazil Contact: José M Baggio Jr, MD jmbaggio@cardiol.br Principal Investigator: José M Baggio Jr, MD Sub-Investigator: Renato Bueno, MD Anis Rassi Hospital Not yet recruiting Goiania, GO, Brazil Contact: Anis Rassi Jr, MD, PhD arassijr@terra.com.br Principal Investigator: Anis Rassi Jr, MD, PhD Hospital das Clínicas de Goiania Not yet recruiting Goiania, GO, Brazil Contact: Salvador Rassi, MD, PhD srassi@cardiol.br Principal Investigator: Salvador Rassi, MD, PhD Santa Casa de Goiania Not yet recruiting Goiania, GO, Brazil Contact: Sérgio Rassi, MD sgrassi@cultura.com.br Contact: Antônio MC Lima, MD antoniomalanc@gmail.com Sub-Investigator: Antonio MC Lima, MD Principal Investigator: Sérgio Rassi, MD Hospital Felício Rocho Not yet recruiting Belo Horizonte, MG, Brazil Contact: Maria CV Moreira, MD, PhD moreiram@cardiol.br Contact: Thiago R Rodrigues, MD thiagorrodrigues@oi.com.br Sub-Investigator: Thiago R Rodrigues, MD Principal Investigator: Maria CV Moreira, MD, PhD Hospital das Clínicas Samuel Libânio Not yet recruiting Pouso Alegre, MG, Brazil Contact: Ricardo A Teixeira, MD, PhD ricardo.alkmim@hotmail.com Principal Investigator: Ricardo A Teixeira, MD, PHD Hospital Escola da Universidade Federal do Triângulo Mineiro Not yet recruiting Uberaba, MG, Brazil Contact: Celso S Melo, MD celsosalgado@uol.com.br Principal Investigator: Celso S Melo, MD Hospital Geral Universitário Not yet recruiting Cuiabá, MT, Brazil Contact: Júlio C Oliveira, MD, PhD juliocesar@atriumcardiologia.com.br Principal Investigator: Júlio C Oliveira, MD, PhD Hospital Universitário Procape Not yet recruiting Recife, PE, Brazil Contact: Dário Sobral Filho, MD, PhD dsobral@uol.com.br Contact: Abelardo G Escarião, MD escariao@hotmail.com Principal Investigator: Dário C Sobral Filho, MD, PhD Sub-Investigator: Adelardo G Escariao, MD Sub-Investigator: Antonio M Nascimento, MD Sub-Investigator: Wilson A Oliveira Jr, MD Hospital Santa Casa de Misericórdia de Curitiba Not yet recruiting Curitiba, PR, Brazil Contact: Gerson Lemke, MD Contact: José CM Jorge, MD, PhD mourajorge@terra.com.br Principal Investigator: Gerson Lemke, MD Sub-Investigator: José CM Jorge, MD, PhD Hospital do Coração de Natal Not yet recruiting Natal, RN, Brazil Contact: Álvaro RB Costa, MD alvaro@digi.com.br Principal Investigator: Álvaro RB Costa, MD Hospital Universitário Onofre Lopes - UFRGN Not yet recruiting Natal, RN, Brazil Contact: Nestor R Oliveira Neto, MD nestor_rn@superig.com.br Principal Investigator: Nestor R Oliveira Neto, MD Hospital das Clínicas da UNICAMP Not yet recruiting Campinas, SP, Brazil Contact: Márcio JO Figueiredo, MD, PhD mjofig@gmail.com Principal Investigator: Márcio JO Figueiredo, MD, PhD Sub-Investigator: Otávio R Coelho, MD Hospital e Maternidade Celso Pierro - PUCC Not yet recruiting Campinas, SP, Brazil Contact: José MN Lima, MD, PhD jmarcolima@gmail.com Contact: Fernando M Porto, MD ritmocamp@hotmail.com Principal Investigator: José MN Lima, MD, PhD Sub-Investigator: Fernando M Porto, MD Sub-Investigator: Halim Cury Filho, MD Hospital do Coração da Fundação de Misericórdia de Franca Not yet recruiting Franca, SP, Brazil Contact: Rodrigo T Silva, MD, PhD rotasil@ig.com.br Principal Investigator: Rodrigo T Silva, MD, PhD Santa Casa de Ribeirão Preto Not yet recruiting Ribeirão Preto, SP, Brazil, 14080-000 Contact: Antonio Vitor Moraes Jr, MD, PhD +55 16 97920407 avitor@terra.com.br Principal Investigator: Antonio Vitor Moraes Jr, MD, PhD HC - FMUSP / Ribeirão Preto Not yet recruiting Ribeirão Preto, SP, Brazil Contact: José A Marin-Neto, MD, Full Prof. marin_neto@yahoo.com Contact: Marcelo G Leal, MD, PhD mgleal@cardiol.br Principal Investigator: José A Marin-Neto, MD, FullProf Principal Investigator: Marcelo G Leal, MD, PhD Sub-Investigator: Elerson Arfelli, MD Sub-Investigator: Andre Schmidt, MD, PhD Sub-Investigator: Adilson Escorzonic, MD Sub-Investigator: Jairo R Silva Jr, MD Sub-Investigator: Henrique T Moreira, MD Sub-Investigator: Maria LRC Pavao, MD Instituto de Moléstias Cardiovasculares Not yet recruiting São José do Rio Preto, SP, Brazil Contact: Adalberto Lorga Filho, MD, PhD lorgafilho@terra.com.br Contact: Oswaldo T Greco, MD oswaldogreco@terra.com.br Principal Investigator: Adalberto Lorga Filho, MD, PhD Sub-Investigator: Rinaldo Santos, MD Heart Institute (InCor) - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo Not yet recruiting São Paulo, SP, Brazil, 05403000 Contact: Martino Martinelli, MD, PhD 55 11 26615515 martino@incor.usp.br Contact: Sergio F Siqueira, Eng, MsC 55 11 26615514 siqueira@incor.usp.br Sub-Investigator: Sérgio F Siqueira, Eng, MsC Sub-Investigator: Giselle L Peixoto, MD Sub-Investigator: Roberto Costa, MD, PhD Sub-Investigator: Maurício I Scanavacca, MD, PhD Sub-Investigator: Antonio CP Barreto, MD, PhD Sub-Investigator: Barbara M Ianni, MD, PhD Sub-Investigator: Denise T Hachul, MD, PhD Sub-Investigator: Edmar Bocchi, MD, PhD Sub-Investigator: Fernando Bacal, MD, PhD Sub-Investigator: Francisco CC Darriex, MD, PhD Sub-Investigator: Germano Souza, MD, PhD Sub-Investigator: Silvana AD Nishioka, MD, PhD Sub-Investigator: Anisio AA Pedrosa, MD, PhD Sub-Investigator: Ricardo A Teixeira, MD, PhD Principal Investigator: Jose Antonio Marin-Neto, Prof Principal Investigator: Anis Rassi Jr, MD, PhD Beneficiência Portuguesa Not yet recruiting São Paulo, SP, Brazil Contact: Silas S Galvão Filho, MD sdsantos@uol.com.br Contact: José TM Vasconcelos, MD, PhD tarr@terra.com.br Principal Investigator: Silas S Galvão Filho Sub-Investigator: José TM Vasconcelos, MD, PhD Escola Paulista de Medicina Not yet recruiting São Paulo, SP, Brazil Contact: Angelo Paola, MD, Full Prof depaola@uol.com.br Contact: Guilherme Fenelon, MD, PhD guilhermefenelon@uol.com.br Principal Investigator: Angelo Paola, MD, Full Prof Sub-Investigator: Guilherme Fenelon, MD, PhD Instituto Dante Pazzanese de Cardiologia Not yet recruiting São Paulo, SP, Brazil Contact: Juan C Pachón, MD juanpachon@gmail.com Principal Investigator: Juan C Pachon, MD Less << |
NCT01173809 | Atrial Fibrillation | Phase 3 | Completed | - | United States, Texas ... More >> St.David's Medical Center Austin, Texas, United States, 78705 Less << |
NCT01097330 | Defibrillators, Implantable ... More >> Tachycardia, Ventricular Less << | Phase 3 | Terminated(Anticipated non-fea... More >>sibility of recruitment objectives) Less << | December 2014 | United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Pennsylvania Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Texas Texas Cardiac Arrhythmia Research Foundation Austin, Texas, United States, 78705 United States, Virginia University of Virginia Health System Charlottesville, Virginia, United States, 22908 Canada, Ontario Hamilton Health Sciences Hamilton, Ontario, Canada, L8L 2X2 Southlake Regional Health Centre Newmarket, Ontario, Canada, L3Y 2P9 University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Canada, Quebec McGill University Health Center Montreal, Quebec, Canada, H3G 1A4 Canada Institut Universitaire de Cardiologie et Pneumologie de Québec Quebec, Canada, G1V 4G5 China Beijng Fuwai Heart Hospital Beijing, China, 100037 Less << |
NCT03413150 | - | Completed | - | - | |
NCT01558128 | Cardiac Disease | Not Applicable | Terminated(Insufficient Recrui... More >>tment) Less << | - | United States, New York ... More >> Weill Cornell Medical College New York, New York, United States, 10065 Less << |
NCT01558128 | - | Terminated(Insufficient Recrui... More >>tment) Less << | - | - | |
NCT00845780 | Persistent Atrial Fibrillation | Phase 4 | Completed | - | Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands, 9700 RB Less << |
NCT03193749 | Chagas Cardiomyopathy | Phase 3 | Recruiting | December 2020 | Colombia ... More >> Fundación Cardioinfantil - Instituto de Cardiología Recruiting Bogotá, Colombia Contact: Eliana Vaquiro, RN, CCRN 6672727 ext 73200 evaquiro@cardioinfantil.org Less << |
NCT03221764 | Atrial Fibrillation ... More >> Lung Transplant; Complications Less << | Phase 2 | Recruiting | July 31, 2019 | United States, Kentucky ... More >> Jewish Hospital Recruiting Louisville, Kentucky, United States, 40202 Contact: Victor van Berkel, MD, PhD 502-588-7600 victor.vanberkel@ulp.org Principal Investigator: Victor van Berkel, MD, PhD Sub-Investigator: Matthew Fox, MD Sub-Investigator: William Whited, MD Less << |
NCT02668432 | New Onset Atrial Fibrillation ... More >> Severe Sepsis Septic Shock Less << | Phase 4 | Enrolling by invitation | March 2019 | United States, Texas ... More >> University Hospital San Antonio, Texas, United States, 78229 Less << |
NCT01817439 | Atrial Fibrillation | Phase 3 | Unknown | May 2015 | Israel ... More >> Western Galilee Hospital Not yet recruiting Naharia, Israel, 972 Contact: Lilach Shema-didi, PhD 507887538 ext 972 lilach.shema-didi@naharia.health.gov.il Less << |
NCT03432663 | Atrial Fibrillation | Phase 4 | Completed | - | Mexico ... More >> Hospital Universitario "Dr. José Eleuterio González". Universidad Autónoma de Nuevo León Monterrey, Nuevo León, Mexico, 64460 Less << |
NCT02924285 | Heart Diseases ... More >> Cardiomyopathies Ventricular Premature Complexes Less << | Phase 3 | Recruiting | October 2019 | Germany ... More >> Heart Center Leipzig Recruiting Leipzig, Germany Contact: Katharina Schöne, MD schoene_katha@t-online.de Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
1.47mL 0.29mL 0.15mL |
7.33mL 1.47mL 0.73mL |
14.67mL 2.93mL 1.47mL |