Name: Amphotericin B | LNS-AmB; NSC 527017
Brand: Ambeed
SKU: A119196
Rating: 4.6 (75 reviews)

NCT00163111	Candidiasis	Phase 3	Completed	-	-
NCT00370825	Visceral Leishmaniasis	Phase 2	Completed	-	India ... More >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Less <<
NCT00002742	Chronic Myeloproliferative Dis... More >>orders Infection Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Less <<	Phase 3	Completed	-	-
NCT00037206	Aspergillosis	Phase 2 Phase 3	Completed	-	United States, Pennsylvania ... More >> Versicor, Inc. King of Prussia, Pennsylvania, United States, 19406 Less <<
NCT00419770	Mucormycosis	Phase 2	Completed	-	United States, California ... More >> City of Hope National Medical Center Duarte, California, United States, 91010 UCSF San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 United States, Ohio Summa Health Systems Akron, Ohio, United States, 44304 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 United States, Washington Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109 Less <<
NCT00847678	Cryptococcal Meningitis	Phase 2	Terminated	-	South Africa ... More >> Novartis Investigative Site South Africa, South Africa Less <<
NCT00362544	Leukemia	Phase 4	Completed	-	France ... More >> Gilead Sciences Paris, France, 75015 Less <<
NCT00889356	Candidiasis B... More >>acterial Vaginosis Less <<	Phase 3	Unknown	March 2010	Brazil ... More >> Vox Femina Not yet recruiting Jundiaí, SP, Brazil Contact: Rogerio Bonassi Machado, MD Principal Investigator: Rogerio Bonassi Machado, MD Less <<
NCT00419770	-		Completed	-	-
NCT01843309	Patients With Fungic Infection... More >>s Less <<	Phase 4	Terminated(Not possible to com... More >>plete the sample within the estimated time by the use of new antifungals) Less <<	-	Mexico ... More >> Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán México, Mexico, 14000 Less <<
NCT00002306	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, Alabama ... More >> Univ of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, District of Columbia George Washington Univ Med Ctr Washington, District of Columbia, United States, 20037 United States, Florida Univ of South Florida Tampa, Florida, United States, 33612 United States, Georgia Emory Univ School of Medicine Atlanta, Georgia, United States, 30303 Med College of Georgia Augusta, Georgia, United States, 30912 United States, Massachusetts Univ Hosp Boston, Massachusetts, United States, 02118 United States, Michigan Ann Arbor Veterans Administration Med Ctr Ann Arbor, Michigan, United States, 48105 United States, Missouri Washington Univ School of Medicine St. Louis, Missouri, United States, 63108 United States, New York Bronx Veterans Administration / Mount Sinai Hosp Bronx, New York, United States, 10468 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 United States, Ohio Cincinnati Veterans Adm Med Ctr / Univ Hosp Cincinnati, Ohio, United States, 452670405 United States, Texas United States Air Force Med Ctr Lackland Air Force Base, Texas, United States, 782365300 Southwest Texas Methodist Hosp San Antonio, Texas, United States, 78229 Univ TX San Antonio Health Science Ctr San Antonio, Texas, United States, 78284 Less <<
NCT00003315	Infection	Phase 3	Completed	-	United Kingdom ... More >> University of Wales College of Medicine Cardiff, Wales, United Kingdom, CF4 4XN Less <<
NCT01656382	Invasive Cryptococcosis	Phase 4	Completed	-	United States, District of Col... More >>umbia Washington Hospital Center Washington, District of Columbia, United States, 20010 Less <<
NCT00000639	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, California ... More >> USC CRS Los Angeles, California, United States, 90033 Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Florida Univ. of Miami AIDS CRS Miami, Florida, United States, 33136 United States, Hawaii Univ. of Hawaii at Manoa, Leahi Hosp. Honolulu, Hawaii, United States United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 United States, Indiana Indiana Univ. School of Medicine, Infectious Disease Research Clinic Indianapolis, Indiana, United States, 46202 Methodist Hosp. of Indiana Indianapolis, Indiana, United States, 46202 United States, Louisiana Tulane Med. Ctr. - Charity Hosp. of New Orleans, ACTU New Orleans, Louisiana, United States, 70112 United States, Massachusetts Massachusetts General Hospital ACTG CRS Boston, Massachusetts, United States, 02114 Bmc Actg Crs Boston, Massachusetts, United States, 02118 Beth Israel Deaconess Med. Ctr., ACTG CRS Boston, Massachusetts, United States, 02215 United States, Missouri St. Louis ConnectCare, Infectious Diseases Clinic St Louis, Missouri, United States Washington U CRS St. Louis, Missouri, United States United States, New York SUNY - Buffalo, Erie County Medical Ctr. Buffalo, New York, United States, 14215 Beth Israel Med. Ctr. (Mt. Sinai) New York, New York, United States, 10003 Cornell University A2201 New York, New York, United States, 10021 Univ. of Rochester ACTG CRS Rochester, New York, United States, 14642 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States, 27599 Carolinas HealthCare System, Carolinas Med. Ctr. Charlotte, North Carolina, United States Regional Center for Infectious Disease, Wendover Medical Center CRS Greensboro, North Carolina, United States, 27401 United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 45267 The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 43210 United States, Pennsylvania Hosp. of the Univ. of Pennsylvania CRS Philadelphia, Pennsylvania, United States, 19104 Pitt CRS Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT00697944	Sepsis Candid... More >>a Less <<	Phase 4	Unknown	March 2009	France ... More >> Chu Michallon Recruiting Grenoble, France, 38000 Contact: TIMSIT jftimsit@chu-grenoble.fr Hopital Saint Louis Not yet recruiting Paris, France, 75010 Less <<
NCT03399955	PKDL - Post-Kala-Azar Dermal L... More >>eishmanioid Less <<	Phase 2	Recruiting	May 1, 2022	Sudan ... More >> Prof. Elhassan Centre for tropical Medicine Recruiting Doka, Gedaref, Sudan Contact: Brima Musa, MD Less <<
NCT00158730	Invasive Aspergillosis ... More >> Other Fungal Infections Less <<	Phase 3	Completed	-	-
NCT00381394	Leishmaniasis, Visceral	Phase 2	Completed	-	India ... More >> GSK Investigational Site Muzaffarpur, India, 842001 GSK Investigational Site Muzaffarpur, India GSK Investigational Site Patna, India, 800007 Less <<
NCT00986713	Invasive Pulmonary Aspergillos... More >>is Less <<	PHASE4	UNKNOWN	2025-10-10	Beijing Chaoyang Hospital,Affi... More >>liate of Capital Medical University, Beijing, Beijing, 100020, China Less <<
NCT00082537	Neutropenia F... More >>ever Less <<	Phase 2	Completed	-	-
NCT01067443	Primary Visceral Leishmaniasis	Phase 2	Completed	-	Kenya ... More >> Kimalel Health Centre Kimalel, Kenya Sudan Kassab Hospital Kassab, Gedaref, Sudan El Hassan Centre for Tropical Medicine Doka, Gedarif, Sudan Less <<
NCT03577509	Invasive Fungal Disease	Phase 1	Completed	-	China, Shanghai ... More >> Huashan Hospital Affiliated to Fudan University Shanghai, Shanghai, China, 200040 Less <<
NCT00334412	Invasive Aspergillosis	Phase 4	Completed	-	France ... More >> Gilead Sciences Paris, France, 75015 Less <<
NCT00523965	Leishmaniasis, Visceral	Phase 3	Completed	-	India ... More >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Less <<
NCT00002305	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	-
NCT03112031	Meningitis Streptococcal ... More >> Hiv Meningitis Meningoencephalitis Less <<	Phase 2	Recruiting	December 2020	Vietnam ... More >> Cho Ray Hospital Recruiting Ho Chi Minh City, Vietnam Principal Investigator: Hung Le Quoc, MD Sub-Investigator: Ngan Nguyen Thi Thuy, MD Sub-Investigator: Binh Tran Quang, MD Hospital for Tropical Diseases Recruiting Ho Chi Minh City, Vietnam Principal Investigator: Tung Nguyen Le Nhu, MD Sub-Investigator: Mai Nguyen Thi Hoang, MD Sub-Investigator: Lan Nguyen Phu Huong, MD Sub-Investigator: Tai Luong Thi Hue, MD Sub-Investigator: Phu Nguyen Hoan, MD Sub-Investigator: Chau Nguyen Van Vinh, MD Oxford University Clinical Research Unit Active, not recruiting Ho Chi Minh City, Vietnam Less <<
NCT01857479	Allergic Bronchopulmonary Aspe... More >>rgillosis Less <<	Phase 2 Phase 3	Completed	-	India ... More >> Chest Clinic, PGIMER Chandigarh, India, 160012 Less <<
NCT00000708	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, Florida ... More >> Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Louisiana Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, New York Bronx Municipal Hosp Ctr/Jacobi Med Ctr Bronx, New York, United States, 10461 Mem Sloan - Kettering Cancer Ctr New York, New York, United States, 10021 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 Less <<
NCT00326157	Fungus Diseases	Phase 2	Completed	-	Italy ... More >> Gilead Sciences Milan, Italy, 20146 Less <<
NCT00002075	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, California ... More >> Dr Robert Larsen Los Angeles, California, United States, 90033 Less <<
NCT00002159	HIV Infections ... More >> Histoplasmosis Blastomycosis Less <<	Phase 3	Completed	-	United States, Alabama ... More >> UAB Station / Infectious Division Birmingham, Alabama, United States, 35294 United States, Arkansas Univ of Arkansas for Med Sciences Little Rock, Arkansas, United States, 72205 United States, Georgia Division of Infectious Diseases Atlanta, Georgia, United States, 30303 United States, Indiana Division of Inf Diseases/ Indiana Univ Hosp Indianapolis, Indiana, United States, 46202 Community Hosp Indianapolis, Indiana, United States, 46218 United States, Louisiana LSU Med Ctr / Div of Pulmonary & Critical Care Med Shreveport, Louisiana, United States, 71130 United States, Michigan Ann Arbor Veterans Administration Med Ctr Ann Arbor, Michigan, United States, 48105 United States, Missouri Univ of Missouri / Division of Infectious Diseases Kansas City, Missouri, United States, 641082792 Infectious Diseases Association / Research Med Ctr Kansas City, Missouri, United States, 64132 Less <<
NCT00003031	Infection Pul... More >>monary Complications Less <<	Phase 3	Completed	-	-
NCT00670657	Candidemia In... More >>vasive Candidiasis Less <<	Phase 4	Completed	-	Italy ... More >> Gilead Sciences Srl Milan, Italy, 20146 Less <<
NCT00624143	Pediatric Acute Leukemia Induc... More >>tion Less <<	Phase 3	Unknown	-	India ... More >> Institute Rotary Cancer Hospital, All India Institute of Medical Sciences Recruiting New Delhi, Delhi, India, 110029 Contact: SAMEER BAKHSHI, MD 91-11-26588153 sambakh@hotmail.com Less <<
NCT00008359	Cancer	Phase 3	Completed	-	United States, New York ... More >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Less <<
NCT00750737	Invasive Fungal Infections ... More >> Hematologic Malignancies Less <<	Phase 3	Completed	-	United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00391014	Acute Myeloid Leukemia ... More >> Allogeneic Haematopoietic Progenitor Cell Transplant Less <<	Phase 2	Completed	-	Spain ... More >> Hospital de la Santa Creu i Sant Pau Barcelona, Spain Hospital Universitario de la Princesa Madrid, Spain Hospital Universitario de Salamanca Salamanca, Spain Hospital Universitario la Fe Valencia, Spain Less <<
NCT00001646	Acquired Immunodeficiency Synd... More >>rome Aspergillosis HIV Infections Immunologic Deficiency Syndromes Neutropenia Less <<	Phase 3	Completed	-	United States, Maryland ... More >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Less <<
NCT00001017	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Phase 3	Completed	-	United States, California ... More >> UCLA CARE Ctr Los Angeles, California, United States, 90095 United States, Florida Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 462025250 United States, Louisiana Louisiana State Univ School of Medicine New Orleans, Louisiana, United States, 70112 Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, Massachusetts Harvard (Massachusetts Gen Hosp) Boston, Massachusetts, United States, 02114 Beth Israel Deaconess - West Campus Boston, Massachusetts, United States, 02215 United States, New York Jack Weiler Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10465 Montefiore Med Ctr / Bronx Municipal Hosp Bronx, New York, United States, 10467 North Central Bronx Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10467 Bronx Veterans Administration / Mount Sinai Hosp Bronx, New York, United States, 10468 SUNY / Erie County Med Ctr at Buffalo Buffalo, New York, United States, 14215 City Hosp Ctr at Elmhurst / Mount Sinai Hosp Elmhurst, New York, United States, 11373 Beth Israel Med Ctr / Peter Krueger Clinic New York, New York, United States, 10003 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Cornell Univ Med Ctr New York, New York, United States, 10021 Mem Sloan - Kettering Cancer Ctr New York, New York, United States, 10021 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 Mount Sinai Med Ctr New York, New York, United States, 10029 Univ of Rochester Medical Center Rochester, New York, United States, 14642 SUNY - Stony Brook Stony Brook, New York, United States, 117948153 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 Duke Univ Med Ctr Durham, North Carolina, United States, 27710 United States, Ohio Holmes Hosp / Univ of Cincinnati Med Ctr Cincinnati, Ohio, United States, 452670405 Univ Hosp of Cleveland / Case Western Reserve Univ Cleveland, Ohio, United States, 44106 Ohio State Univ Hosp Clinic Columbus, Ohio, United States, 432101228 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 Less <<
NCT00002074	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	-
NCT00002316	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Phase 1	Completed	-	United States, California ... More >> Los Angeles County - USC Med Ctr Los Angeles, California, United States, 90033 UCI Med Ctr Orange, California, United States, 92668 UCSD Treatment Ctr San Diego, California, United States, 92103 United States, Kansas Univ of Kansas School of Medicine Wichita, Kansas, United States, 67214 United States, New York SUNY / Health Sciences Ctr at Stony Brook Stony Brook, New York, United States, 117948153 United States, North Carolina Duke Univ Med Ctr Durham, North Carolina, United States, 27710 East Carolina Univ School of Medicine Greenville, North Carolina, United States, 278584354 Bowman Gray School of Medicine Winston Salem, North Carolina, United States, 271571042 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 United States, Pennsylvania Pennsylvania State Univ / Hershey Med Ctr Hershey, Pennsylvania, United States, 17033 United States, Texas Univ TX Galveston Med Branch Galveston, Texas, United States, 775550882 Less <<
NCT00235651	Lung Transplantation\|Lung Dise... More >>ases Less <<	PHASE3	TERMINATED	2025-04-06	University of Pittsburgh Medic... More >>al Center, Pittsburgh, Pennsylvania, 15213, United States Less <<
NCT00750737	-		Completed	-	-
NCT00002068	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, California ... More >> Davies Med Ctr San Francisco, California, United States, 94114 United States, Delaware Christiana Hosp / Med Ctr of Delaware Wilmington, Delaware, United States, 19899 United States, Florida Univ of South Florida Tampa, Florida, United States, 33612 United States, Maryland Univ of Maryland / Inst of Human Virology Baltimore, Maryland, United States, 212011192 United States, Michigan Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New York Harlem AIDS Treatment Group / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Tennessee Univ of Tennessee Memphis, Tennessee, United States, 38163 Canada, Ontario Saint Michael's Hosp Toronto, Ontario, Canada Less <<
NCT00386997	Fungal Infection	Phase 4	Terminated(Study closed due to... More >> recruitment challenges.) Less <<	-	Germany ... More >> Gilead Sciences GmbH Martinsried/Munich, Germany, 82152 Less <<
NCT02527928	-		Unknown	February 2016	-
NCT00002277	Mycoses HIV I... More >>nfections Less <<	Phase 3	Completed	-	United States, Texas ... More >> Dr Layne Gentry Houston, Texas, United States, 77030 Dr Temple Williams Houston, Texas, United States, 77030 M D Anderson Cancer Ctr Houston, Texas, United States, 77030 Less <<
NCT00106288	Candidiasis	Phase 3	Completed	-	-
NCT01122771	Visceral Leishmaniasis	Phase 3	Completed	-	Bangladesh ... More >> Bhaluka UZHC Bhaluka, Mymensingh, Bangladesh Gaffargaon Gaffargaon, Mymensingh, Bangladesh Community Based Medical College Trishal, Mymensingh, Bangladesh Trishal UZHC Trishal, Mymensingh, Bangladesh Less <<
NCT00263315	Aspergillosis	Phase 2 Phase 3	Completed	-	Netherlands ... More >> Erasmus MC centrumlocatie Rotterdam, Netherlands Erasmus MC locatie Daniel den Hoed Rotterdam, Netherlands Less <<
NCT00003938	Cancer	Phase 3	Completed	-	-
NCT01293643	Vaginosis, Bacterial ... More >> Candidiasis, Vulvovaginal Less <<	Phase 3	Completed	-	-
NCT00936910	Central Line Fungal Infections	Phase 4	Completed	-	United States, Pennsylvania ... More >> Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania, United States, 15224 Less <<
NCT00936910	-		Completed	-	-
NCT00047827	Aspergillosis	Phase 2	Terminated(Inadequate enrollme... More >>nt) Less <<	-	United States, District of Col... More >>umbia Washington, District of Columbia, United States, 20010 United States, Georgia Atlanta, Georgia, United States, 30322 United States, Michigan Ann Arbor, Michigan, United States, 48109 Detroit, Michigan, United States, 48201 United States, Missouri St. Louis, Missouri, United States, 63110 United States, Tennessee Memphis, Tennessee, United States, 38105 United States, Texas Houston, Texas, United States, 77030 Less <<
NCT00002019	Meningitis, Cryptococcal ... More >> HIV Infections Less <<	Not Applicable	Completed	-	United States, California ... More >> Harbor - UCLA Med Ctr Torrance, California, United States, 90502 United States, Connecticut Dr Thomas Patterson New Haven, Connecticut, United States, 06510 United States, District of Columbia Walter Reed Army Med Ctr Washington, District of Columbia, United States, 203075001 United States, Illinois Rush Presbyterian - Saint Luke's Med Ctr Chicago, Illinois, United States, 60612 United States, Maryland Natl Naval Med Ctr Bethesda, Maryland, United States, 20889 United States, Massachusetts Univ Hosp Boston, Massachusetts, United States, 02118 United States, New Jersey East Orange Veterans Administration Med Ctr East Orange, New Jersey, United States, 07018 Saint Michael's Med Ctr Newark, New Jersey, United States, 07102 United States, New York Beth Israel Med Ctr / Peter Krueger Clinic New York, New York, United States, 10003 Dr Dorothy Friedberg New York, New York, United States, 10016 New York Univ Med Ctr New York, New York, United States, 10016 Cornell Univ Med College New York, New York, United States, 10021 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 Mount Sinai Med Ctr / Jack Martin Fund Clinic New York, New York, United States, 10029 Mount Sinai Med Ctr New York, New York, United States, 10029 United States, Pennsylvania Buckley Braffman Stern Med Associates Philadelphia, Pennsylvania, United States, 19107 United States, Texas Univ TX Galveston Med Branch Galveston, Texas, United States, 77550 Audie L Murphy Veterans Administration Hosp San Antonio, Texas, United States, 78284 United States, Utah Univ of Utah School of Medicine Salt Lake City, Utah, United States, 84132 Less <<
NCT00161356	Liver Transplantation	Phase 4	Terminated(Budget issues)	-	United States, Texas ... More >> Memorial Hermann Hospital Houston, Texas, United States, 77030 Less <<
NCT00145249	Cryptococcal Meningitis	Phase 2	Completed	-	United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35255 United States, California University of Southern California Los Angeles, California, United States, 90033 Harbor-UCLA Medical Center Los Angeles, California, United States, 90502 United States, Colorado University of Colorado Denver, Colorado, United States, 80291-0238 United States, Florida University of Florida Gainesville, Florida, United States, 32610 University of Miami Miami, Florida, United States, 33136-1096 United States, Louisiana Tulane University Health Sciences Center New Orleans, Louisiana, United States, 70112 United States, Michigan Harper University Hospital Detroit, Michigan, United States, 48201 United States, Texas Texas Medical Center - Michael E. DeBakey Veterans Affairs Houston, Texas, United States, 77030 The University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Thailand Ramathibodi Hospital, Mahidol University Bangkok, Thailand, 10400 Mahidol University - Siriraj Hospital - Medicine Bangkok, Thailand, 10700 Chiang Mai University Chiang Mai, Thailand, 50200 Khon Kaen University Khon Kaen, Thailand, 40002 Bamrasnaradura Institution Nonthaburi, Thailand, 11000 Less <<
NCT00001065	Candidiasis, Oral\|HIV Infectio... More >>ns Less <<	PHASE2	COMPLETED	1998-04-01	Alabama Therapeutics CRS, Birm... More >>ingham, Alabama, 35294, United States\|USC CRS, Los Angeles, California, United States\|Santa Clara Valley Med. Ctr., San Jose, California, United States\|San Mateo County AIDS Program, San Mateo, California, United States\|Howard University Hosp., Div. of Infectious Diseases, ACTU, Washington, District of Columbia, 20059, United States\|Univ. of Miami AIDS CRS, Miami, Florida, United States\|The Ponce de Leon Ctr. CRS, Atlanta, Georgia, United States\|Queens Med. Ctr., Honolulu, Hawaii, 96816, United States\|Univ. of Hawaii at Manoa, Leahi Hosp., Honolulu, Hawaii, 96816, United States\|Northwestern University CRS, Chicago, Illinois, 60611, United States\|Cook County Hosp. CORE Ctr., Chicago, Illinois, 60612, United States\|Weiss Memorial Hosp., Chicago, Illinois, 60640, United States\|Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States\|Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, 46202, United States\|Indiana Univ. School of Medicine, Wishard Memorial, Indianapolis, Indiana, 46202, United States\|Methodist Hosp. of Indiana, Indianapolis, Indiana, 46202, United States\|Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, 21287, United States\|Massachusetts General Hospital ACTG CRS, Boston, Massachusetts, 02114, United States\|Bmc Actg Crs, Boston, Massachusetts, 02118, United States\|St. Louis ConnectCare, Infectious Diseases Clinic, Saint Louis, Missouri, 63112, United States\|Washington U CRS, Saint Louis, Missouri, United States\|Univ. of Nebraska Med. Ctr., Durham Outpatient Ctr., Omaha, Nebraska, 68198, United States\|SUNY - Buffalo, Erie County Medical Ctr., Buffalo, New York, 14215, United States\|Beth Israel Med. Ctr. (Mt. Sinai), New York, New York, 10029, United States\|NY Univ. HIV/AIDS CRS, New York, New York, United States\|Univ. of Rochester ACTG CRS, Rochester, New York, 14642, United States\|Univ. of Cincinnati CRS, Cincinnati, Ohio, 45267, United States\|The Ohio State Univ. AIDS CRS, Columbus, Ohio, 43210, United States\|Hosp. of the Univ. of Pennsylvania CRS, Philadelphia, Pennsylvania, 19104, United States\|University of Washington AIDS CRS, Seattle, Washington, 98122, United States\|Puerto Rico-AIDS CRS, San Juan, 00936, Puerto Rico\|Mbeya Med. Research Program, Mbeya Referral Hosp. CRS, Mbeya, Tanzania Less <<
NCT01437020	Leishmaniasis ... More >> Effects of Immunotherapy Less <<	Phase 1 Phase 2	Withdrawn(Drug Product no long... More >>er available.) Less <<	-	India ... More >> Kala-Azar Medical Research Center (KAMRC), Rambag Road Muzaffarpur, India Banaras Hindu University Varanasi, India Less <<
NCT00002041	Candidiasis, Esophageal\|HIV In... More >>fections Less <<		COMPLETED	-	Bristol - Myers Squibb Co, Pri... More >>nceton, New Jersey, 085434000, United States Less <<
NCT00451711	Acute Myeloid Leukemia	Phase 2	Unknown	October 2014	Australia, Victoria ... More >> The Alfred Hosptial Not yet recruiting Melbourne, Victoria, Australia, 3004 Principal Investigator: C. Orla Morrissey, MB, BCh, FRACP Principal Investigator: Anthony P Schwarer, MB, BS, FRACP, MD, FRCPA Sub-Investigator: Sushrat Patil, MB, BS, FRACP, FRCPA Box Hill Hospital, Eastern Health Recruiting Melbourne, Victoria, Australia, 3129 Contact: Anthony P Schwarer, MB, BS, FRACP, MD, FRCPA +61 3 9895 3333 anthony.schwarer@boxhill.org.au Principal Investigator: Anthony P. Schwarer, MB, BS, FRACP, MD, FRCPA Less <<
NCT02971007	Vulvovaginitis ... More >> Yeast Infection Yeast Infection Vaginal Candidiasis, Vulvovaginal Less <<	Phase 2	Completed	-	-
NCT01254708	Lung Transplant Recipient	Phase 2	Suspended(Study has been place... More >>d on hold due to unavailability of funding.) Less <<	January 2014	Canada, Ontario ... More >> University Health Network/ Toronto General Hospital Toronto, Ontario, Canada, M5G 2N2 Less <<
NCT02971007	-		Completed	-	-
NCT03187691	Acute Myeloid Leukemia ... More >> Acute Lymphoblastic Leukemia Less <<	Phase 2	Not yet recruiting	April 2020	-
NCT00145249	-		Completed	-	-
NCT00310505	Visceral Leishmaniasis	Not Applicable	Completed	-	India ... More >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 221005 Less <<
NCT02273661	Allergic Bronchopulmonary Aspe... More >>rgillosis Less <<	Phase 2	Active, not recruiting	February 19, 2020	France ... More >> Chu de Poitiers Poitiers, France, 86000 Less <<
NCT00497601	Visceral Leishmaniasis	Phase 2	Completed	-	India ... More >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Less <<
NCT03656081	Chronic Pulmonary Aspergillosi... More >>s Less <<	Phase 3	Not yet recruiting	May 2023	-
NCT00421187	Febrile Neutropenia	Phase 4	Terminated(Unable to recruit s... More >>ubjects in the Turkey site.) Less <<	-	Greece ... More >> Gilead Sciences Athens, Greece, 167 77 Less <<
NCT03529617	-		Recruiting	December 31, 2020	Belgium ... More >> UZ Leuven Recruiting Leuven, Belgium, 3000 Contact: Ruth Van Daele, PharmD +3216343264 ruth.vandaele@uzleuven.be Less <<
NCT00418951	-		Completed	-	-
NCT00418951	Acute Myelogenous Leukemia ... More >> Myelodysplastic Syndrome Less <<	Phase 2	Completed	-	United States, Texas ... More >> The University of Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00148148	Hematopoietic Stem Cell Transp... More >>lantation Fungus Diseases Less <<	Phase 2	Completed	-	Germany ... More >> KKS Münster University Hospital Münster, NRW, Germany, 48145 Less <<
NCT03167957	Vulvovaginal Candidiases ... More >> Yeast Infection Vulvovaginitis Yeast Infection Vaginal Candidiasis, Vulvovaginal Less <<	Phase 2	Not yet recruiting	June 2019	United States, Michigan ... More >> Tolan Park Clinic Not yet recruiting Detroit, Michigan, United States, 48201 Principal Investigator: Jack D Sobel, MD Less <<
NCT01945281	Candidiasis, Invasive	Phase 2	Terminated(Operational feasibi... More >>lity with low recruitment due to changing epidemiology of disease) Less <<	-	-
NCT00177710	Lung Transplantation\|Fungal In... More >>fections Less <<	PHASE3	COMPLETED	2025-12-07	University of Pittsburgh Medic... More >>al Center, Pittsburgh, Pennsylvania, 15213, United States Less <<
NCT00832208	Visceral Leishmaniasis	Phase 2	Terminated	-	Ethiopia ... More >> Arba Minch LRTC Arba Minch, Ethiopia Gondar Gondar, Ethiopia Sudan Kassab Hospital Kassab, Gedarif, Sudan Less <<
NCT01566552	Visceral Leishmaniasis	Phase 4	Unknown	December 2017	India ... More >> Kala Azar Medical Research Center Not yet recruiting Muzaffarpur, Bihar, India, 842001 Contact: DEEPAK VERMA, MBBS 916212287570 KMARCMFP@HOTMAIL.COM Less <<
NCT00815516	Candidiasis	Phase 3	Terminated(It was decided to d... More >>iscontinue the study due to insufficient recruitment.) Less <<	-	United States, California ... More >> Children's Hospital of Orange County Orange, California, United States, 92868 United States, New Jersey UMDNJ/Robert Wood Johnson Medical School New Brunswick, New Jersey, United States, 08901 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 WakeMed Health and Hospitals Raleigh, North Carolina, United States, 27610 United States, Virginia Virginia Commonwealth University Richmond, Virginia, United States, 23298 Brazil Irmandade da Santa Casa de Misericórdia de Belo Horizonte Belo Horizonte, Minas Gerais, Brazil, 30150-221 Hospital de Base da Faculdade de Medicina São José do Rio Preto, Sao Paulo, Brazil, 15090-000 Bulgaria Spec Hospital for Active Treatment of Children Diseases Sofia, Bulgaria, 1606 Canada, Ontario McMaster Children's Hospital Hamilton, Ontario, Canada, L8N 3Z5 Colombia Hospital Pablo Tobon Uribe Medellin, Antioque, Colombia, 574 Greece University Hospital of Patras Patras, Greece, 26504 Hungary Semmelweis Egyetem Budapest, Hungary, 8200 Israel Hadassah University Hospital Ein Kerem Jerusalem, Israel, 91120 Philippines Philippine General Hospital Manila, Philippines Romania Emergency County Clinical Hospital Cluj-Napoca, Romania, 400006 Turkey Cukurova University Medical Faculty Adana, Turkey, 1330 Ukraine Municipal Institution "Odesa Regional Children's Hospital" Odesa, Ukraine, 65031 Less <<
NCT02686853	Cryptococcal Meningitis	Phase 4	Unknown	-	-
NCT00815516	-		Terminated(It was decided to d... More >>iscontinue the study due to insufficient recruitment.) Less <<	-	-
NCT00425620	Chronic Sinusitis	Phase 3	Completed	-	-
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NCT02011958	Visceral Leishmaniasis	Phase 3	Unknown	April 2017	Ethiopia ... More >> MSF Abdurafi, Ethiopia Leishmaniasis Research Center, University Hospital of Gondar Gondar, Ethiopia Less <<
NCT01032187	Visceral Leishmaniasis	Phase 4	Completed	-	Brazil ... More >> Hospital de Doenças Tropicais Araguaína, Tocantins, Brazil Hospital Dona Regina Palmas, Tocantins, Brazil Less <<
NCT01259713	-		Completed	-	-
NCT00628719	Visceral Leishmaniasis	Phase 3	Completed	-	India ... More >> Kala-azar Medical Research Center, Rambag Road Muzaffarpur, India, 842001 Less <<
NCT00371995	Visceral Leishmaniasis	Phase 2	Completed	-	India ... More >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Rajendra Memorial Research Institute of Medical Sciences Patna, Bihar, India Less <<
NCT02136030	Cryptococcal Meningitis	Not Applicable	Unknown	December 2016	Taiwan ... More >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Less <<
NCT01652859	Normal Healthy Subjects	Phase 1	Completed	-	-
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NCT02629419	Candidiasis, Chronic Mucocutan... More >>eous Less <<	PHASE2	COMPLETED	2022-08-06	National Institute of Allergy ... More >>and Infectious Disease (NIAID), Bethesda, Maryland, 20892, United States Less <<
NCT01303549	Liver Disease ... More >> Fungal Infection Less <<	Phase 4	Completed	-	Spain ... More >> Hospital Clinic i Provincial Barcelona, Spain Hospital de Bellvitge Barcelona, Spain Hospital Vall d'Hebrón Barcelona, Spain Hospital de Cruces Bilbao, Spain Hospital Reina Sofia Córdoba, Spain Complexo Hospitalario de A Coruña La Coruña, Spain Hospital Doce de Octubre Madrid, Spain Hospital Gregorio Marañón Madrid, Spain Hospital Ramón y Cajal Madrid, Spain Hospital Carlos Haya Malaga, Spain Hospital Central de Asturias Oviedo, Spain Hospital Marqués de Valdecilla Santander, Spain Less <<
NCT00876824	Leishmaniasis, Visceral	Phase 3	Completed	-	India ... More >> Muzaffarpur, Bihar, India, 842001 Muzaffarpur, Bihar, India, 842003 Patna, Bihar, India, 800001 Patna, Bihar, India, 800007 Less <<
NCT01845727	Cutaneous Leishmaniasis	Phase 1 Phase 2	Completed	-	Colombia ... More >> Programa de Estudios y Control de Enfermedades Tropicales (PECET), Universidad de Antioquia Medellin, Colombia Less <<
NCT02025491	Disseminated Leishmaniasis	Phase 3	Completed	-	Brazil ... More >> HUPES Salvador, Bahia, Brazil, 40000 Less <<
NCT02283905	Blastomycosis	Phase 4	Suspended(Manufacturer of amph... More >>otericin-B deoxycholate cannot supply at this time.) Less <<	December 2018	Canada, Manitoba ... More >> St. Boniface General Hospital Winnipeg, Manitoba, Canada, R2H 2A6 Less <<
NCT02656797	Leishmaniasis	Phase 2	Recruiting	January 2021	Israel ... More >> Soroka University Medical Center Recruiting Beer Sheva, Israel Contact: Amir Horev amirhor@clalit.org.il Less <<
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NCT01615809	-		Completed	-	-
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NCT03511820	-		Completed	-	Taiwan ... More >> Changhua Christian Hospital Changhua, Taiwan, 500 Kaohsiung Veterans General Hospital Kaohsiung, Taiwan, 81362 Kaohsiung Chang Gung Memorial Hospital Kaohsiung, Taiwan, 833 Keelung Chang Gung Memorial Hospital Keelung, Taiwan, 204 China Medical University Hospital Taichung City, Taiwan, 40447 Tri-Service General Hospital Taipei city, Taiwan, 114 Taipei Veterans General Hospital Taipei, Taiwan, 11212 Taipei Mucinipal Wanfang Hospital Taipei, Taiwan, 116 Chang Guang Memorial Hospital at LinKou Taoyuan, Taiwan, 333 Less <<
NCT03636659	Visceral Leishmaniasis	Phase 1	Recruiting	March 2019	Bangladesh ... More >> International Centre for Diarrhoeal Disease Research b Not yet recruiting Dhaka, Bangladesh, 1212 Contact: Dr. Dinesh Mondal, MD 1712027091 din63d@icddrb.org Contact: Dr. Shomik Maruf, MBBS 1673587409 shomik.maruf@icddrb.org Principal Investigator: Dr. Dinesh Mondal, MD India Kala-Azar medical Research Centre Recruiting Muzaffarpur, Bihar, India, 842001 Contact: Dr. Shyam Sundar, MD 9453048500 drshyamsundar@hotmail.com Contact: Tauseeb Malik, B.Pharm 8299225413 tauseebmalik8574@gmail.com Principal Investigator: Dr. Shyam Sundar, MD Rajendra Memorial Research Institute of Medical Sciences Recruiting Patna, Bihar, India, 800007 Contact: Dr. Krishna Pandey, MD 9431042119 drkrishnapandey@yahoo.com Contact: Ms.Ranjeeta , Diploma 8553626714 ranjeetaraj96@gmail.com Principal Investigator: Dr. Krishna Pandey, MD Less <<
NCT02660645	-		Recruiting	December 2020	United States, California ... More >> USC/Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Ileana Aldana 323-865-0702 ileana.aldana@med.usc.edu Principal Investigator: Sia Daneshmand, MD Sub-Investigator: Anne Schuckman, MD Sub-Investigator: Mihir Desai, MD Sub-Investigator: Hooman Djaladat, MD Sub-Investigator: Gerhard Fuchs, MD Sub-Investigator: Virinder Bhardwaj, MD VA Palo Alto Health Care System Recruiting Palo Alto, California, United States, 94304 Contact: Dorothy Trivedi dtrivedi@stanford.edu Principal Investigator: Joseph Liao, MD Sub-Investigator: James Crotty, MD Sub-Investigator: John Leppert, MD Sub-Investigator: John Lavelle, MD University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Contact: Sima Porten, MD, MPH 415-885-3695 Sima.Porten@ucsf.edu Principal Investigator: Sima Porten, MD, MPH United States, Kansas University of Kansas Medical Center Recruiting Kansas City, Kansas, United States, 66160 Contact: Katie Glavin 913-588-8721 kglavin@kumc.edu Principal Investigator: John Taylor, MD, MS Sub-Investigator: Jeffrey Holzbeierlein, MD, FACS Sub-Investigator: Eugene Lee, MD, FACS Sub-Investigator: Hadley Wyre, MD Sub-Investigator: Moben Mirza, MD United States, Maryland Johns Hopkins Medicine Recruiting Baltimore, Maryland, United States, 21224 Contact: Morgan De Carli Mdecarl2@jhmi.edu Principal Investigator: Trinity Bivalacqua, MD, PhD Sub-Investigator: Phillip Pierorazio, MD United States, Minnesota University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Therese Perrier 612-625-3319 perri084@umn.edu Principal Investigator: Badrinath Konety, MD Sub-Investigator: Weight Chris, MD Sub-Investigator: Laureen Hemsley, MD United States, New York Stony Brook Urology Recruiting Stony Brook, New York, United States, 11794 Contact: Kim Lyktey Kim.Lyktey@stonybrookmedicine.edu Principal Investigator: John Fitzgerald, MD Sub-Investigator: Massimiliano Spaliviero, MD Sub-Investigator: Wayne Waltzer, MD United States, Ohio Cincinnati VA Medical Center Not yet recruiting Cincinnati, Ohio, United States, 45220 Contact: Krishnanath Gaitonde, MD Principal Investigator: Krishnanath Gaitonde, MD Ohio State University Wexner Medical Center Recruiting Columbus, Ohio, United States, 43210 Contact: Kamal Pohar, MD kamal.pohar@osumc.edu Principal Investigator: Kamal Pohar, MD Sub-Investigator: Megan Merrill, DO Sub-Investigator: Ahmad Shabsigh, MD Sub-Investigator: David Sharp, MD United States, South Carolina Carolina Urology Partners Recruiting West Columbia, South Carolina, United States, 29169 Contact: Nicol Brandon 704-414-2870 ext 2809 Nicol.brandon@carolinaurologypartners.com Principal Investigator: T. Brian Willard, MD Sub-Investigator: David Lamb, MD Sub-Investigator: Scott Sweazy, MD Sub-Investigator: Keith Birghtbill, MD Sub-Investigator: Michael Stotzer, MD United States, Texas UT Southwestern Not yet recruiting Dallas, Texas, United States, 75390 Contact: Yair Lotan, MD 214-645-8787 Principal Investigator: Yair Lotan, MD Sub-Investigator: Aditya Bagrodia, MD Sub-Investigator: Vitaly Margulis, MD Sub-Investigator: Ganesh Raj, MD, PhD Michael E. DeBakey VA Medical Center Recruiting Houston, Texas, United States, 77030 Contact: Ashley Jones, BS, CCRP 713-791-1414 ext 26694 Ashley.Jones2@bcm.edu Principal Investigator: Jennifer Taylor, MD, MPH Sub-Investigator: Jeffrey Jones, MD Sub-Investigator: Sidney Worsham, MD United States, West Virginia Charleston Area Medical Center Recruiting Charleston, West Virginia, United States, 25301 Contact: James Tierney, DO 304-388-9944 Principal Investigator: James Tierney, DO Sub-Investigator: Samuel Deem, DO Less <<
NCT02439749	Hypertension ... More >>Vascular Diseases Cardiovascular Diseases Less <<	Not Applicable	Recruiting	December 2022	-
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NCT00260559	-		Recruiting	December 2050	United States, Pennsylvania ... More >> University of Pittsburgh Medical Center - Heart, Lung, and Esophageal Surgical Institute Recruiting Pittsburgh, Pennsylvania, United States, 15213 Contact: Julie A. Ward, BSN 412-647-8583 wardj@upmc.edu Principal Investigator: James D. Luketich, MD Sub-Investigator: Neil A. Christie, MD Sub-Investigator: Arjun Pennathur, MD Sub-Investigator: Matthew Schuchert, MD Sub-Investigator: Manisha Shende, MD Sub-Investigator: Lawrence Crist, MD Sub-Investigator: Ryan Levy, MD Sub-Investigator: Omar Awais, DO Sub-Investigator: Katie Nason, MD Sub-Investigator: Kevin McGrath, MD Sub-Investigator: Angela Gallagher, CRNP Sub-Investigator: Jason Lamb, MD Sub-Investigator: Jonathan D'Cunha, MD Sub-Investigator: Rajeev Dhupar, MD Sub-Investigator: Inderpal Sarkaria, MD Sub-Investigator: Manuel Villa Sanchez, MD Sub-Investigator: Jadsada Athigakunagorn, MD Sub-Investigator: Nicholas Baker, MD UPMC - Hillman Cancer Center Recruiting Pittsburgh, Pennsylvania, United States, 15232 Contact: Julie A. Ward, BSN 412-647-8583 wardj@upmc.edu Less <<
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CAS No. :	1397-89-3
Formula :	C₄₇H₇₃NO₁₇
M.W :	924.08
SMILES Code :	C[C@H]([C@@H](O)[C@@H](C)[C@H](C)OC1=O)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@]2([H])O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@]3([H])[C@H](C(O)=O)[C@@H](O)C[C@](C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C1)(O)O3
Synonyms :	LNS-AmB; NSC 527017; Fungizone
MDL No. :	MFCD00877763

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H315-H319-H335
Precautionary Statements:	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Mouse Embryonic Fibroblasts (MEFs)	25 ng/ml		Used for culturing MEFs to study the effect of GPC1 on cell migration	Oncogene. 2012 May 17;31(20):2535-44.
Human and mice immune cells	250 ng/mL		Used for the culture of immune cells to maintain a sterile environment.	Cell Death Dis. 2019 Feb 8;10(2):113.
Human and mice stromal cells	250 ng/mL		Used for the culture of stromal cells to maintain a sterile environment.	Cell Death Dis. 2019 Feb 8;10(2):113.
bone marrow-derived macrophages (BMM)	5 μg/ml	3 weeks	Used to inhibit fungal growth to assess the growth of Mycobacterium tuberculosis.	mBio. 2022 Oct 26;13(5):e0108622.
L. major promastigotes	207 nM	44 h	Determine the growth inhibitory activity of Amphotericin B against L. major promastigotes, EC50 was 207 nM	PLoS Negl Trop Dis. 2009 Nov 3;3(11):e540.
L. major axenic amastigote-like parasites	380 nM	144 h	Determine the growth inhibitory activity of Amphotericin B against L. major axenic amastigote-like parasites, EC50 was 380 nM	PLoS Negl Trop Dis. 2009 Nov 3;3(11):e540.

Mice	Wild-type mice	Oral	0.2 mL of 0.1 mg/ml	Every 12 hours for three days	To deplete the gut microbiota in mice for studying its impact on pancreatic tumors	Cancer Res. 2020 Mar 1;80(5):1088-1101
Mice	Chronic Social Defeat Stress model	Intraperitoneal injection	1 mg/kg	Single injection	Amphotericin B liposomes reversed and prevented behavioral abnormalities in mice induced by chronic social defeat stress (CSDS) by activating the innate immune system.	Front Pharmacol. 2022 Jul 15;13:918177
Mice	Antibiotic-induced gut microbiota depletion model	Gavage	1 mg/kg	Every 12 hours for three days	To study the effect of Amphotericin B on sleep promotion in mice through antibiotic-induced gut microbiota depletion. The results showed that antibiotic treatment blocked Amphotericin B-induced alterations in sleep behavior and increases in 5-HT levels.	Sci Rep. 2021 Jul 1;11(1):13660
Mice	Pasteurella multocida type‐A (PmCQ2) infection model	Drinking water	0.1 mg/mL	Continued for 3 weeks	To investigate the impact of intestinal mycobiota dysbiosis on lung inflammation, the results showed that Amphotericin B treatment increased mortality and lung bacterial loads, and enhanced the production of inflammatory cytokines in the serum and lung.	Imeta. 2024 Sep 14;3(5):e241
Balb/c mice	L. major infection model	Subcutaneous injection	12.5 mg/kg	Once daily for 21 days	Evaluate the efficacy of Amphotericin B in the L. major infected mouse model, results showed Amphotericin B effectively reduced footpad swelling	PLoS Negl Trop Dis. 2009 Nov 3;3(11):e540.
Mice	C57BL/6J mice	Oral	0.2 g/L	Water changes every 3 days for 2 weeks	Used for antibiotic pre-treatment to eliminate the regulatory activity of the IH microbiota	Cell Host Microbe. 2022 Sep 14;30(9):1295-1310.e8

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CAS No.: 1397-89-3

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CAS No.: 1397-89-3

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Product Details of Amphotericin B

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Precautionary Statements-General

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Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed