Home Cart Sign in  
Chemical Structure| 1177827-73-4 Chemical Structure| 1177827-73-4

Structure of AP-III-a4
CAS No.: 1177827-73-4

Chemical Structure| 1177827-73-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

ENOblock is a small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM) and inhibit cancer cell metastasis in vivo.

Synonyms: ENOblock

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of AP-III-a4

CAS No. :1177827-73-4
Formula : C31H43FN8O3
M.W : 594.72
SMILES Code : O=C(CC1=CC=C(C=C1)NC2=NC(NCC3CCCCC3)=NC(NCC4=CC=C(C=C4)F)=N2)NCCOCCOCCN
Synonyms :
ENOblock
MDL No. :MFCD28009373
InChI Key :MOVYITHKOHMLHC-UHFFFAOYSA-N
Pubchem ID :24012277

Safety of AP-III-a4

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
AP-III-a4 is a novel nonsubstrate analogue inhibitor of enolase, exhibiting an IC50 of 0.576 μM, making it relevant for cancer and diabetes research[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.68mL

0.34mL

0.17mL

8.41mL

1.68mL

0.84mL

16.81mL

3.36mL

1.68mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

Categories