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Chemical Structure| 2559703-06-7 Chemical Structure| 2559703-06-7

Structure of Apostatin-1
CAS No.: 2559703-06-7

Chemical Structure| 2559703-06-7

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Apostatin-1 (Apt-1) is a highly efficient TRADD inhibitor that binds TRADD-N (KD=2.17 μM), preventing its interaction with TRADD-C and TRAF2, regulating RIPK1 and Beclin 1 ubiquitination. Additionally, Apt-1 activates autophagy in cells with mutated tau, α-synuclein, or huntingtin, inhibits apoptosis, and restores cellular homeostasis.

Synonyms: Apt-1

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Product Details of Apostatin-1

CAS No. :2559703-06-7
Formula : C19H27N3OS
M.W : 345.50
SMILES Code : O=C(NC1CCCCCC1)C(SC2=NCCN2C)C3=CC=CC=C3
Synonyms :
Apt-1

Safety of Apostatin-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Apostatin-1

pyroptosis

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1 mM

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2.89mL

0.58mL

0.29mL

14.47mL

2.89mL

1.45mL

28.94mL

5.79mL

2.89mL

 

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