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Chemical Structure| 170729-80-3 Chemical Structure| 170729-80-3

Structure of Aprepitant
CAS No.: 170729-80-3

Chemical Structure| 170729-80-3

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Aprepitant is a selective and high-affinity neurokinin-1 receptor antagonist with IC50 of 0.1 nM.

Synonyms: MK-0869; MK-869; ONO-7436

4.5 *For Research Use Only !

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Product Details of Aprepitant

CAS No. :170729-80-3
Formula : C23H21F7N4O3
M.W : 534.43
SMILES Code : O=C1NNC(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)OCC2)=N1
Synonyms :
MK-0869; MK-869; ONO-7436
InChI Key :ATALOFNDEOCMKK-OITMNORJSA-N
Pubchem ID :135413536

Safety of Aprepitant

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00428519 HIV Infections Phase 1 Completed - United States, Pennsylvania ... More >> Clinical Trials Unit. University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01757210 - Completed - United States, West Virginia ... More >> WVU Healthcare Morgantown, West Virginia, United States, 26506 Less <<
NCT01405924 - Terminated(Low enrollment) - -
NCT00080444 Vomiting Phase 3 Completed - -
NCT02519842 Chemotherapy-induced Nausea an... More >>d Vomiting Less << Phase 3 Terminated(Further data are no... More >> longer required to support an application for use in pediatric patients. The decision to terminate was not based on any new safety findings) Less << - -
NCT00711555 - Completed - -
NCT01405924 Nausea Vomiti... More >>ng Less << Phase 2 Terminated(Low enrollment) - -
NCT03197064 Postoperative Nausea Phase 4 Not yet recruiting January 31, 2019 United States, California ... More >> Stanford University Medical Center Not yet recruiting Palo Alto, California, United States, 94305 Contact: Mark A Burbridge, MD    650-353-8484    markburb@stanford.edu    Contact: Richard A Jaffe, MD, PhD    (650) 723-6411    rajaffe@stanford.edu    Principal Investigator: Mark A Burbridge, MD          Sub-Investigator: Richard A Jaffe, MD, PhD          Sub-Investigator: Jaime R Lopez, MD Less <<
NCT03514381 Soft Tissue Sarcoma Phase 4 Recruiting July 2020 France ... More >> Institut Bergonie Not yet recruiting Bordeaux, France, 33076 Contact: Maud TOULMONDE, MD    05 56 33 32 78    m.toulmonde@bordeaux.unicancer.fr    Institut Regional Du Cancer de Montpellier (Icm) Not yet recruiting Montpellier, France, 34298 Contact: Nelly FIRMIN, MD    04 67 61 45 65    nelly.firmin@icm.unicancer.fr    Institut Universitaire Du Cancer de Toulouse - Oncopole Recruiting Toulouse, France, 31059 Contact: Thibaud VALENTIN, MD    05 31 15 51 51    valentin.thibaud@iuct-oncopole.fr Less <<
NCT02519842 - Terminated(Further data are no... More >> longer required to support an application for use in pediatric patients. The decision to terminate was not based on any new safety findings) Less << - -
NCT01625455 Sezary Syndrome ... More >> Pruritus Less << Phase 4 Terminated(Difficulty recruiti... More >>ng.) Less << - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37235 Less <<
NCT01111851 - Completed - -
NCT00726960 Opioid-Related Disorders ... More >> Heroin Dependence Substance-Related Disorders Less << Phase 1 Unknown June 2010 Sweden ... More >> Karolinska University Hospital, Huddinge Stockholm, Sweden, 14186 Less <<
NCT00711555 Nausea Vomiti... More >>ng Less << Phase 2 Completed - United States, Illinois ... More >> University of Illinois Medical Center Chicago, Illinois, United States, 60612 Less <<
NCT01625455 - Terminated(Difficulty recruiti... More >>ng.) Less << - -
NCT01534637 Extrahepatic Bile Duct Cancer ... More >> Nausea Vomiting Stage II Pancreatic Cancer Stage III Pancreatic Cancer Stage IV Pancreatic Cancer Less << Phase 2 Completed - United States, North Carolina ... More >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Less <<
NCT00651755 Lymphoma Not Applicable Completed - United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00818259 Chemotherapy-Induced Nausea an... More >>d Vomiting Less << Phase 1 Terminated(Study terminated ea... More >>rly prior to completing targeted enrollment of participants <6 months of age due to recruitment challenges.) Less << - -
NCT01111851 Chemotherapy-Induced Nausea an... More >>d Vomiting (CINV) Less << Phase 1 Completed - -
NCT00651755 - Completed - -
NCT00818259 - Terminated(Study terminated ea... More >>rly prior to completing targeted enrollment of participants <6 months of age due to recruitment challenges.) Less << - -
NCT01534637 - Completed - -
NCT00499668 Myeloproliferative Disorders ... More >> Leukemia Lymphoma Lymphoproliferative Disorder Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Nausea and Vomiting Solid Tumor Less << Not Applicable Withdrawn(slow accrual) - -
NCT00734929 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Completed - United States, North Carolina ... More >> Duke University Medical Center Durham, North Carolina, United States, 27710 Less <<
NCT00734929 - Completed - -
NCT02550119 Malignant Digestive System Neo... More >>plasm Nausea and Vomiting Less << Not Applicable Terminated(Insufficient accrua... More >>l) Less << - United States, California ... More >> USC / Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 Less <<
NCT00990821 Chemotherapy-Induced Nausea an... More >>d Vomiting Postoperative Nausea and Vomiting Less << Phase 1 Completed - -
NCT00990821 - Completed - -
NCT00293384 - Completed - -
NCT00415103 Leukemia Lymp... More >>homa Less << Phase 4 Completed - Spain ... More >> Hospital Universitario Gregorio Marañón Madrid, Spain Hospital Universitario La Paz Madrid, Spain Hospital Universitario la Princesa Madrid, Spain Hospital Clínico Universitario de Salamanca Salamanca, Spain Hospital Universitario Marqués de Valdecilla Santander, Spain Less <<
NCT00588835 Tumor Phase 4 Terminated - Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands Radboud University Nijmegen Medical Centre Nijmegen, Netherlands Less <<
NCT01440673 Postoperative Nausea and Vomit... More >>ing Less << COMPLETED 2025-09-10 Gil Medical Center Gachon Univ... More >>ersity, Inchon, 405-760, Korea, Republic of Less <<
NCT02811055 Type 2 Diabetes ... More >> Hypertension Less << Phase 2 Recruiting July 2019 France ... More >> Rouen University Hospital Recruiting Rouen, France Principal Investigator: Gaétan PREVOST, MD Less <<
NCT00293384 Breast Cancer ... More >> Chronic Myeloproliferative Disorders Gestational Trophoblastic Tumor Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Nausea and Vomiting Neuroblastoma Ovarian Cancer Testicular Germ Cell Tumor Less << Not Applicable Completed - United States, Michigan ... More >> Barbara Ann Karmanos Cancer Institute Detroit, Michigan, United States, 48201-1379 Less <<
NCT02525848 Postoperative Nausea and Vomit... More >>ing Less << Phase 2 Phase 3 Completed - Egypt ... More >> Hala saad Abdel-Ghaffar Assiut, Assiut governorate, Egypt, 715715 Less <<
NCT00250744 Cancer Phase 2 Completed - United States, New Mexico ... More >> University of New Mexico Albuquerque, New Mexico, United States, 87131 Less <<
NCT00738621 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Completed - United States, Texas ... More >> Scott and White Healthcare Temple, Texas, United States, 76508 Less <<
NCT01362530 Chemotherapy Induced Nausea an... More >>d Vomiting Less << Phase 3 Completed - -
NCT01362530 - Completed - -
NCT02364804 Non-small Cell Lung Cancer COMPLETED 2025-09-15 Shiga University of Medical Sc... More >>ience Hospital, Otsu, Shiga, 520-2192, Japan Less <<
NCT01474915 Postoperative Nausea and Vomit... More >>ing (PONV) Nausea Less << Phase 4 Completed - United States, Ohio ... More >> The Ohio State University Wexner Medical Center Columbus, Ohio, United States, 43210 Less <<
NCT01474915 - Completed - -
NCT00248547 - Completed - -
NCT01176591 Cocaine Alcoh... More >>ol Dependence Less << Phase 2 Terminated - United States, Pennsylvania ... More >> University of Pennsylvania, Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01636947 - Completed - -
NCT01017809 Ovarian Cancer WITHDRAWN 2025-12-13 NYU Clinical Cancer Center, Ne... More >>w York, New York, 10016, United States Less <<
NCT00977223 Healthy Volunteers Phase 4 Completed - France ... More >> Rouen Clinical research Centre (CIC 0204) Rouen, Haute Normandie, France, 76031 Less <<
NCT01183481 Nausea Vomiti... More >>ng Less << Phase 2 Terminated(Study was stopped d... More >>ue to inadequate accrual.) Less << - Canada, Ontario ... More >> Odette Cancer Centre, Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N3M5 Less <<
NCT01183481 - Terminated(Study was stopped d... More >>ue to inadequate accrual.) Less << - -
NCT01636947 Nausea Vomiti... More >>ng Less << Phase 4 Completed - -
NCT00719173 Breast Cancer ... More >> Nausea and Vomiting Less << Phase 1 Completed - United States, North Carolina ... More >> Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill, North Carolina, United States, 27599-7295 Less <<
NCT00248547 Cancer Not Applicable Completed - United States, Oregon ... More >> OHSU Knight Cancer Institute Portland, Oregon, United States, 97239-3098 Less <<
NCT00835965 Nausea Vomiti... More >>ng Less << Not Applicable Unknown - United States, Pennsylvania ... More >> Lankenau Hospital Wynnewood, Pennsylvania, United States, 19096 Less <<
NCT01186029 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Withdrawn(It didn't get IRB ap... More >>proval.) Less << October 2011 United States, Nebraska ... More >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 Less <<
NCT01101529 Nausea Vomiti... More >>ng Less << Phase 2 Completed - Sweden ... More >> Uppsala University Hospital Uppsala, Sweden, 75185 Less <<
NCT00659945 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Completed - United States, Pennsylvania ... More >> UPMC Magee Women's Hospital Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT00659945 - Completed - -
NCT00869310 Emesis Phase 3 Terminated(we terminated the s... More >>tudy before enrolling 303/560 due to a slow accrual) Less << - Italy ... More >> Fausto Roila Terni, Italy, 05100 Less <<
NCT00954941 Hematologic Diseases ... More >> Acute Myelogenous Leukemia Myelodysplastic Syndrome Chronic Myelogenous Leukemia Less << Phase 2 Completed - United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00956215 Nausea Vomiti... More >>ng Less << Not Applicable Completed - United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT00954941 - Completed - -
NCT00945321 Chemotherapy-Induced Nausea an... More >>d Vomiting Less << Phase 1 Completed - -
NCT00869973 Emesis Phase 3 Terminated(We terminated the s... More >>tudy after enrolling 580/900 patients due to a slow accrual) Less << - Italy ... More >> Fausto Roila Terni, Italy, 05100 Less <<
NCT00945321 - Completed - -
NCT01020903 - Completed - -
NCT01088022 Nausea Vomiti... More >>ng Less << Phase 3 Unknown April 2013 Italy ... More >> Azienda Ospedaliera di Perugia - Hematology dept. Not yet recruiting Perugia, Italy, 06100 Principal Investigator: Leonardo Flenghi, M.D. Less <<
NCT00429754 Nausea|Vomiting PHASE4 WITHDRAWN 2025-09-08 -
NCT00572572 Germ Cell Tumors Phase 3 Completed - United States, Indiana ... More >> Indiana University Simon Cancer Center Indianapolis, Indiana, United States, 46202 Medical Consultants, P.C. Muncie, Indiana, United States, 47303 United States, Missouri Siteman Cancer Center St. Louis, Missouri, United States, 63110 United States, Oregon Providence Portland Medical Center Portland, Oregon, United States, 97213 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Wisconsin Froedtert/Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Less <<
NCT01020903 Postoperative Nausea Not Applicable Completed - United States, New York ... More >> Staten Island University Hospital Staten Island, New York, United States, 10305 Less <<
NCT00699894 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Withdrawn(Logistical difficult... More >>ies running the study) Less << - United States, New York ... More >> Long Island Jewish Medical Center/Schneider's Children Hospital New Hyde Park, New York, United States, 11040 Less <<
NCT00736073 Pancreatitis Not Applicable Completed - United States, North Carolina ... More >> Duke University Medical Center Durham, North Carolina, United States, 27710 Less <<
NCT00314743 Nausea Vomiti... More >>ng Less << Early Phase 1 Completed - United States, Missouri ... More >> Washington University School of Medicine St. Louis, Missouri, United States, 63110 Less <<
NCT00736073 - Completed - -
NCT01732458 Post-operative Nausea ... More >> Post-operative Vomiting Less << Phase 2 Completed - -
NCT00659737 - Completed - -
NCT01732458 - Completed - -
NCT00572572 - Completed - -
NCT02058277 Healthy Phase 1 Completed - United States, Florida ... More >> Pfizer Investigational Site DeLand, Florida, United States, 32720 Less <<
NCT03572829 Vomiting|Nausea Post Chemother... More >>apy|Head Neck Cancer Less << PHASE2 COMPLETED 2020-07-01 National Cancer Center/ Cancer... More >> Hospital, Chinese Academy of Medcal science and Peking Union Medical College, Beijing, China Less <<
NCT01432015 Ovarian Cancer ... More >> Uterine Cancer Less << Phase 4 Completed - United States, California ... More >> Gynecologic Oncology Associates Newport Beach, California, United States, 92663 Less <<
NCT01432015 - Completed - -
NCT00659737 Nausea Vomiti... More >>ng Less << Not Applicable Completed - United States, Pennsylvania ... More >> Hahnemann University Hospital Philadelphia, Pennsylvania, United States, 19102 Less <<
NCT01536691 Cancer Malign... More >>ancy Less << Phase 3 Unknown February 2013 Korea, Republic of ... More >> Hyo Jung Kim Recruiting Anyang, Gyeonggi-do, Korea, Republic of, 431070 Contact: Hyo Jung Kim, M.D., Ph.D.    82313803704    hemonc@hallym.or.kr    Principal Investigator: Hyo Jung Kim, M.D., Ph.D. Less <<
NCT01450826 Nausea Vomiti... More >>ng Glioma Less << Phase 2 Completed - United States, North Carolina ... More >> The Preston Robert Tisch Brain Tumor Center at Duke Durham, North Carolina, United States, 27710 Less <<
NCT01450826 - Completed - -
NCT02431286 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Unknown December 2015 Brazil ... More >> Angela Maria Sousa Recruiting Sao Paulo, São Paulo, Brazil, 01403010 Contact: angela sousa, phD    3893-2000 ext 6680    angela.sousa@icesp.org.br    Sub-Investigator: Thiago Grigio, MD          Principal Investigator: angela sousa, phD          Sub-Investigator: hazem ashmawi, phD Less <<
NCT02597907 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Completed - -
NCT02597907 - Completed - -
NCT00888329 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Terminated(Slow accrual.) - United States, Arizona ... More >> Mayo Clinic Phoenix, Arizona, United States, 85054 Less <<
NCT00888329 - Terminated(Slow accrual.) - -
NCT02336750 Breast Cancer Phase 3 Recruiting December 2019 China ... More >> Fudan University Cancer Hospital Recruiting Shanghai, China, 200032 Contact: Xichun Hu, MD,PhD    64175590 ext 5006    huxicun@gmail.com    Contact: Jun Cao, MD    64175590 ext 5009    caojun1115lemon@163.com Less <<
NCT02909478 Chemotherapy-induced Nausea an... More >>d Vomiting Colorectal Cancer Less << Phase 3 Unknown - -
NCT00717054 - Completed - -
NCT02933099 Chemotherapy-induced Nausea an... More >>d Vomiting Less << Phase 3 Unknown December 2018 -
NCT00970905 Nausea Vomiti... More >>ng Less << Phase 2 Completed - United States, Arizona ... More >> Mayo Clinic Arizona Scottsdale, Arizona, United States, 85259-5499 United States, North Carolina Wake Forest Baptist Health Winston-Salem, North Carolina, United States, 27157 United States, Vermont Fletcher Allen Health Care Burlington, Vermont, United States, 05401 Less <<
NCT03237611 Chemotherapy-induced Nausea an... More >>d Vomiting Less << Phase 2 Not yet recruiting September 18, 2018 -
NCT01344304 Colorectal Cancer Not Applicable Unknown March 2014 Japan ... More >> Kansai Rosai Hospital Recruiting Amagasaki, Hyogo, Japan, 6600064 Contact: Rei Suzuki          Kinki Central Hospital Recruiting Itami, Hyogo, Japan, 6640872 Contact: Takamichi Komori          Kawasaki Hospital Recruiting Kobe, Hyogo, Japan, 6520042 Contact: Toshihiro Kimura          Nara Hospital Kinki University Faculty of Medicine Recruiting Ikoma, Nara, Japan, 6300293 Contact: Kotaro Kitani          Higashiosaka City General Hospital Recruiting Higashi-Osaka, Osaka, Japan, 5788588 Contact: Masaki Okuyama          Saito Yukoukai Hospital Recruiting Ibaraki, Osaka, Japan, 5670085 Contact: Taro Hayashi    0726416898       Rinku General Medical Center Recruiting Izumisano, Osaka, Japan, 5988577 Contact: Hitoshi Mizuno          Kaizuka City Hospital Recruiting Kaizuka, Osaka, Japan, 5970015 Contact: Hiroshi Nakano          Hannan Chuo Hospital Recruiting Matsubara, Osaka, Japan, 5800023 Contact: Isao Arai          Minoh City Hospital Recruiting Minoo, Osaka, Japan, 5620014 Contact: Yasuhiro Miyake          Sakai City Hospital Recruiting Sakai, Osaka, Japan, 5900064 Contact: Hiroyoshi Takemoto          Osaka Rosai Hospital Recruiting Sakai, Osaka, Japan, 5918025 Contact: Hajime Hirose          Suita Municipal Hospital Recruiting Suita, Osaka, Japan, 5640082 Contact: Takashi Yoshino          Saiseikai Senri Hospital Recruiting Suita, Osaka, Japan, 5650862 Contact: Hirofumi Ota          Graduate School of Medicine / Faculty of Medicine, Osaka University Recruiting Suita, Osaka, Japan Contact: Junichi Nishimura       jnishimura@gesurg.med.osaka-u.ac.jp    Toyonaka Municipal Hospital Recruiting Toyonaka, Osaka, Japan, 5608565 Contact: Taishi Hata          Yao Municipal Hospital Recruiting Yao, Osaka, Japan, 5810069 Contact: Yoshihito Ide          Kenporen Osaka Central Hospital Recruiting Osaka, Japan, 5300001 Contact: Masato Yoshikawa    0647955505       Iseikai Hospital Recruiting Osaka, Japan, 5330022 Contact: Takahiko Tanigawa          Osaka Medical Center for Cancer and Cardiovascular Diseases Recruiting Osaka, Japan, 5378511 Contact: Tatsushi Shingai          National Hospital Organization Osaka National Hospital Recruiting Osaka, Japan, 5400006 Contact: Masayoshi Yasui          NTT West Osaka Hospital Recruiting Osaka, Japan, 5430042 Contact: Katsuki Danno          Nissay Hospital Recruiting Osaka, Japan, 5500012 Contact: Shohei Maeda          Tane General Hospital Recruiting Osaka, Japan, 5500024 Contact: Atsuhiro Ogawa          Osaka Seninhoken Hospital Recruiting Osaka, Japan, 5520021 Contact: Yasunori Watanabe          Osaka Koseinenkin Hospital Recruiting Osaka, Japan, 5530003 Contact: Makoto Fujii    06-6441-5451       Osaka General Medical Center Recruiting Osaka, Japan, 5588558 Contact: Hiroshi Tamagawa Less <<
NCT02357693 Postoperative Nausea and Vomit... More >>ing Less << PHASE4 COMPLETED 2025-08-15 Angela Maria Sousa, Sao Paulo,... More >> S?o Paulo, 01403010, Brazil Less <<
NCT01046461 Solid Tumour ... More >>Postoperative Nausea and Vomiting Less << Phase 2 Unknown June 2012 Korea, Republic of ... More >> Hallym University Sacred Heart Hospital Anyang-si, Gyeonggi-do, Korea, Republic of, 431-070 Less <<
NCT02445872 Chemotherapy-Induced Nausea an... More >>d Vomiting Lung Cancer Less << Phase 2 Unknown May 2016 China, Zhejiang ... More >> The first affiliated hospital, Zhejiang University Hangzhou, Zhejiang, China, 310003 Less <<
NCT00819039 Postoperative Nausea and Vomit... More >>ing Less << Phase 1 Completed - United States, Kentucky ... More >> Call for Information (Investigational Site 0003) Louisville, Kentucky, United States, 40202 United States, Tennessee Call for Information (Investigational Site 0022) Nashville, Tennessee, United States, 37232 Brazil MSD Sao Paulo, SP, Brazil, 04717-004 Mexico MSD Mexico City, Mexico, 1090 Spain Merck Sharp and Dohme de Espana S.A. Madrid, Spain, 28027 Turkey Merck Sharp & Dohme Ilaclari Ltd. Sti Istanbul, Turkey Less <<
NCT02576327 Vomiting Phase 4 Unknown December 2017 -
NCT00717054 Nausea Vomiti... More >>ng Less << Not Applicable Completed - United States, Pennsylvania ... More >> Hahnemann University Hospital Philadelphia, Pennsylvania, United States, 19102 Less <<
NCT02407600 Non-small Cell Lung Cancer ... More >> Vomiting Nausea Emesis Less << Phase 2 Unknown February 2018 United States, New York ... More >> SUNY Upstate Medical University Not yet recruiting Syracuse, New York, United States, 13210 Contact: Kristine Garcia, BS    315-464-5934       Contact: Dena Martin, BS    3154645262       Principal Investigator: Ajeet Gajra, MD FACP Less <<
NCT00819039 - Completed - -
NCT03245918 Chemotherapy-induced Nausea an... More >>d Vomiting Less << Phase 1 Completed - Canada, Ontario ... More >> Hospital for Sick Children Toronto, Ontario, Canada, M5G 1X8 Less <<
NCT02226601 Cognitive Dysfunction Not Applicable Unknown - United States, Arizona ... More >> University of Arizona Medical Center Recruiting Tucson, Arizona, United States, 85724 Principal Investigator: Kai Schoenhage, MD Less <<
NCT02989467 Healthy Phase 1 Completed - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less <<
NCT01300988 HIV Infection Phase 1 Completed - United States, Pennsylvania ... More >> Clinical Trials Unit. University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104--607 Less <<
NCT02979548 Chemotherapy Induced Vomiting ... More >> Acute Myeloid Leukemia Less << Phase 3 Recruiting December 2018 India ... More >> Irch, Aiims , New Delhi , India Recruiting New Delhi, DEL, India, 110029 Contact: ATUL SHARMA, MD    9968859779    dratulsharma@hotmail.com Less <<
NCT02097823 Chemotherapy Induced Nausea an... More >>d Vomiting Less << Phase 2 Completed - United States, Indiana ... More >> Riley Hospital for Children at Indiana University Health Indianapolis, Indiana, United States, 46202 Less <<
NCT01874119 Chemotherapy-induced Nausea an... More >>d Vomiting Less << Phase 2 Terminated(Enrollment issues) - United States, Missouri ... More >> Saint Louis University Hospital Saint Louis, Missouri, United States, 63101 Less <<
NCT02205164 Chemotherapy Induced Nausea an... More >>d Vomiting Less << Phase 2 Unknown October 2014 Italy ... More >> Università-Azienda Policlinico di Bari Active, not recruiting Bari, BA, Italy, 70124 Ospedale Perrino Recruiting Brindisi, BR, Italy, 72010 Contact: Angela Melpignano, MD       brinemat@tin.it    Principal Investigator: Angela Melpignano, MD          Ospedale Pugliese-Ciacco Active, not recruiting Catanzaro, CZ, Italy, 88100 IRCCS Casa Sollievo della Sofferenza Recruiting San Giovanni Rotondo, FG, Italy, 71013 Contact: Nicola Cascavilla, MD       nicola.cascavilla@tin.it    Principal Investigator: Nicola Cascavilla, MD          Ospedale Vito Fazzi Recruiting Lecce, LE, Italy, 73100 Contact: Nicola Di Renzo, MD       direnzo.ematolecce@libero.it    Principal Investigator: Nicola Di Renzo, MD          Ospedale "Cardinale Panico" Recruiting Tricase, LE, Italy, 73100 Contact: Vincenzo Pavore, MD       salentoematologia@piafondazionepanico.it    Principal Investigator: Vincenzo Pavone, MD          A.O. Riuniti Papardo - Piemonte Recruiting Messina, ME, Italy, 98121 Contact: Donato Mannina, MD       donadani@tiscali.it    Principal Investigator: Donato Mannina, MD          Casa di Cura "La Maddalena" Recruiting Palermo, PA, Italy, 90127 Contact: Maurizio Musso, MD       mamusso@libero.it    Principal Investigator: Maurizio Musso, MD          Ospedale Ascoli Civico Palermo Recruiting Palermo, PA, Italy, 90127 Contact: Anxur Merenda, MD       anxurmerenda@libero.it    Principal Investigator: Anxur Merenda, MD          Ospedale Moscati Recruiting Taranto, TA, Italy, 74100 Contact: Patrizio Mazza, MD       ematologia.taranto@libero.it    Principal Investigator: Patrizio Mazza, MD          ARON " Cardarelli" Recruiting Napoli, Italy, 80121 Contact: Felicetto Ferrara, MD       felicettoferrara@katamail.com    Principal Investigator: Felicetto Ferrara, MD Less <<
NCT02097823 - Completed - -
NCT01149369 Gastroparesis Phase 3 Completed - United States, California ... More >> California Pacific Medical Center San Francisco, California, United States, 94115 Stanford University Stanford, California, United States, 94305-5187 United States, Kentucky University of Louisville Louisville, Kentucky, United States, 40202 United States, Maryland Johns Hopkins Bayview Medical Center Baltimore, Maryland, United States, 21224 United States, Michigan University of Michigan Medical Center Ann Arbor, Michigan, United States, 48109 United States, North Carolina Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 United States, Pennsylvania Temple University Hospital Philadelphia, Pennsylvania, United States, 19140 United States, Texas Texas Tech University Health Sciences Center El Paso, Texas, United States, 79905 Less <<
NCT01874119 - Terminated(Enrollment issues) - -
NCT01249001 Nausea Vomiti... More >>ng Chemotherapy Less << Phase 2 Terminated(lack of eligible pa... More >>rticipants to enrol) Less << - Canada, Ontario ... More >> The Hospital for Sick Children Toronto, Ontario, Canada, M5G 1X8 Less <<
NCT01334086 Acute Myeloid Leukemia PHASE2 COMPLETED 2013-08-30 Princess Margaret Hospital, To... More >>ronto, Ontario, M5G 2M9, Canada Less <<
NCT01012336 Chemotherapy-Induced Nausea an... More >>d Vomiting Ovarian Cancer Less << Phase 2 Completed - Korea, Republic of ... More >> Samsung Medical Center Seoul, Korea, Republic of Less <<
NCT01897337 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Completed - Korea, Republic of ... More >> Gangnam severance hospital Seoul, Korea, Republic of Less <<
NCT02347878 Leukemia|Lymphoma PHASE4 UNKNOWN 2025-12-15 Sun Yat-sen University Cancer ... More >>Center, Guangzhou, Guangdong, 510060, China Less <<
NCT02646020 Non-small Cell Lung Cancer Phase 2 Unknown December 2017 China, Guangdong ... More >> Cancer Center of Sun-Yat Sen University (CCSYSU) GuangZhou, Guangdong, China, 510060 Less <<
NCT01012336 - Completed - -
NCT02532634 Cancer Tumors Phase 4 Completed - Korea, Republic of ... More >> St. Vincent`S Hospital Suwon, Gyeonggi, Korea, Republic of, 16247 Keimyung University Dongsan Medical Center Daegu, Korea, Republic of Chungnam National University Hospita Daejeon, Korea, Republic of Pusan National University Hospital Pusan, Korea, Republic of Kangbuk Samsung Hospital Seoul, Korea, Republic of Kangdong Sacred Heart Hospital Seoul, Korea, Republic of Samsung Medical Center Seoul, Korea, Republic of Seoul St. Mary's Hospital Seoul, Korea, Republic of Severance Hospital Seoul, Korea, Republic of Ajou University Hospital Suwon, Korea, Republic of Less <<
NCT01527994 Opioid Dependence Phase 1 Completed - United States, New York ... More >> Bellevue Hospital Center & the NYU School of Medicine New York, New York, United States, 10016 Less <<
NCT01683552 ITCH Phase 2 Completed - Italy ... More >> Campus Bio-Medico of Rome University Roma, Italy, 00128 Less <<
NCT01661335 Nausea Vomiti... More >>ng Childhood Cancer Less << Phase 3 Recruiting December 2018 United States, Oklahoma ... More >> Jimmy Everest Center for Cancer and Blood Disorders in Children Recruiting Oklahoma City, Oklahoma, United States, 73104 Principal Investigator: Rene McNall-Knapp, MD Less <<
NCT01074255 - Completed - -
NCT02161991 Carcinoma, Non-small Cell Lung Phase 3 Unknown December 2017 China, Hunan ... More >> Hunan province tumor hospital Recruiting Changsha, Hunan, China Contact: Chunhua Zhou, MD    +86 731 89762321    zhouchunhua@hnszlyy.com Less <<
NCT02939287 Nausea Vomiti... More >>ng Less << Phase 3 Unknown November 2018 -
NCT01963793 Pruritus Phase 2 Completed - Germany ... More >> Allergie-Zentrum-Charité, Charité - Universitätsmedizin Berlin Berlin, Germany, D-10117 Less <<
NCT01074255 - Completed - -
NCT01402024 Chemotherapy Induced Nausea an... More >>d Vomiting Less << Phase 3 Completed - India ... More >> Dr. BRA IRCH, AIIMS New Delhi, Delhi, India, 110029 Less <<
NCT02154360 HIV Infection PHASE1 COMPLETED 2025-06-16 Hospital of the University of ... More >>Pennsylvania Clinical Research Site, Philadelphia, Pennsylvania, 19104, United States Less <<
NCT01298193 Breast Cancer PHASE4 COMPLETED 2025-04-14 Corporació Sanitaria Parc Taul... More >>í, Sabadell, Barcelona, 08208, Spain|Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, 28805, Spain|Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, 28922, Spain|Complejo Hospitalario Universitario A Coru?a, A Coru?a, 15006, Spain|Centro Oncológico de Galicia, A Coru?a, 15009, Spain|Hospital del Mar, Barcelona, 08003, Spain|Hospital Clinic i Provincial, Barcelona, 08036, Spain|Complejo Hospitalario de Jaén, Jaén, 23007, Spain|Hospital Universitario Arnau de Vilanova de Lleida, Lleida, 25189, Spain|Complejo Hospitalario Xeral-Calde, Lugo, 27004, Spain|Hospital Clínico Universitario San Carlos, Madrid, 28040, Spain|Hospital Arnau de Vilanova de Valencia, Valencia, 46015, Spain|Hospital Clínico Universitario Lozano Blesa, Zaragoza, 50009, Spain Less <<
NCT00212602 Malignant Tumor PHASE2 COMPLETED - Chubu Region Facility, Chubu, ... More >>Japan|Chugoku Region Facility, Chugoku, Japan|Hokkaido Region Facility, Hokkaido, Japan|Hokuriku Region Facility, Hokuriku, Japan|Kanto Region Facility, Kanto, Japan|Kinki Region Facility, Kinki, Japan|Kyushu Region Facility, Kyushu, Japan|Shikoku Region Facility, Shikoku, Japan|Tohoku Region Facility, Tohoku, Japan Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.87mL

0.37mL

0.19mL

9.36mL

1.87mL

0.94mL

18.71mL

3.74mL

1.87mL

References

 

Historical Records

Categories