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Chemical Structure| 2166548-12-3 Chemical Structure| 2166548-12-3

Structure of AR-13324 mesylate
CAS No.: 2166548-12-3

Chemical Structure| 2166548-12-3

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AR-13324 mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter which inhibits kinases ROCK1 and ROCK2 with a Ki of 1 nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16 nM, respectively, and blocked the profibrotic effects of TGF-β2 in HTM cells.

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Product Details of AR-13324 mesylate

CAS No. :2166548-12-3
Formula : C29H31N3O6S
M.W : 549.64
SMILES Code : O=C(OCC1=CC=C([C@@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C.CS(=O)(O)=O
MDL No. :MFCD31807687

Safety of AR-13324 mesylate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of AR-13324 mesylate

cytoskeleton

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.82mL

0.36mL

0.18mL

9.10mL

1.82mL

0.91mL

18.19mL

3.64mL

1.82mL

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